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CSIR-NET Life Sciences
Unit 1. Molecules and their Interaction Relevant to Biology
A. Structure of atoms, molecules and chemical bonds
B. Composition, structure and function of biomolecules (carbohydrates, lipids, proteins, nucleic acids and vitamins)
C. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding, hydrophobic interaction, etc.)
D. Principles of biophysical chemistry (pH, buffer, reaction kinetics, thermodynamics, colligative properties).
E. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group transfer, biological energy transducers.
F. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation, mechanism of enzyme catalysis, isozymes
G. Conformation of proteins (Ramachandran plot, secondary structure, domains, motif and folds).
H. Conformation of nucleic acids (helix (A, B, Z), tRNA, micro-RNA).
I. Stability of proteins and nucleic acids.
J. Metabolism of carbohydrates, lipids, amino acids nucleotides and vitamins.
Unit 2. Cellular Organization
A) Membrane structure and function
B) Structural organization and function of intracellular organelles
C) Organization of genes and chromosomes
D) Cell division and cell cycle
E) Microbial Physiology
Unit 3. Fundamental Processes
A) DNA replication, repair and recombination
B) RNA synthesis and processing
C) Protein synthesis and processing
D) Control of gene expression at transcription and translation level
Unit 4. Cell Communication and Cell Signaling
A) Host parasite interaction
B) Cell signaling
C) Cellular communication
D) Cancer
E) Innate and adaptive immune system (Immunology)
Unit 5. Developmental Biology
A) Basic concepts of development
B) Gametogenesis, fertilization and early development
C) Morphogenesis and organogenesis in animals
D) Morphogenesis and organogenesis in plants
E) Programmed cell death, aging and senescence
Unit 6. System Physiology – Plant
A) Photosynthesis
B) Respiration and photorespiration
C) Nitrogen metabolism
D) Plant hormones
E) Sensory photobiology
F) Solute transport and photoassimilate translocation
G) Secondary metabolites
H) Stress physiology
Unit 7. System Physiology – Animal
A) Blood and circulation
B) Cardiovascular System
C) Respiratory system
D) Nervous system
E) Sense organs
F) Excretory system
G) Thermoregulation
H) Stress and adaptation
I) Digestive system
J) Endocrinology and reproduction
Unit 8. Inheritance Biology
A) Mendelian principles
B) Concept of gene
C) Extensions of Mendelian principles
D) Gene mapping methods
E) Extra chromosomal inheritance
F) Microbial genetics
G) Human genetics
H) Quantitative genetics
I) Mutation
J) Structural and numerical alterations of chromosomes
K) Recombination
Unit 9. Diversity of Life Forms
A) Principles & methods of taxonomy
B) Levels of structural organization
C) Outline classification of plants, animals & microorganisms
D) Natural history of Indian subcontinent
E) Organisms of health & agricultural importance
F) Organisms of conservation concern
Unit 10. Ecological Principles
A) The Environment
B) Habitat and Niche
C) Population Ecology
D) Species Interactions
E) Community Ecology
F) Ecological Succession
G) Ecosystem Ecology
H) Biogeography
I) Applied Ecology
J) Conservation Biology:
Unit 11. Evolution and Behavior
A) Emergence of evolutionary thoughts
B) Origin of cells and unicellular evolution:
C) Paleontology and Evolutionary History:
D) Molecular Evolution
E) The Mechanisms
F) Brain, Behavior and Evolution
Unit 12. Applied Biology
A) Microbial fermentation and production of small and macro molecules
B) Application of immunological principles, vaccines, diagnostics. Tissue and cell culture methods for plants and animals
C) Transgenic animals and plants, molecular approaches to diagnosis and strain identification
D) Genomics and its application to health and agriculture, including gene therapy
E) Bioresource and uses of biodiversity
F) Breeding in plants and animals, including marker – assisted selection
G) Bioremediation and phytoremediation
H) Biosensors
Unit 13. Methods in Biology
A) Molecular Biology and Recombinant DNA methods
B) Histochemical and Immunotechniques
C) Biophysical Method
D) Statisitcal Methods
E) Radiolabeling techniques
F) Microscopic techniques
G) Electrophysiological methods
H) Methods in field biology
General Aptitude
Number System and simplification
Average
Calendar
Series Formation
Clock
Speed Time and Distance
L.C.M. & H.C.F
Mensuration
Geometry
Test Discussion 17 July
Test 1 17 July
Unit 1 Test 20 July 22
Unit 1 Test 20 July 22
Unit 1 Test 20 July
Unit 1 Test 20 July 22
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Ramachandran Plot
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