Previous Year Questions

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QUESTION ID:16

In which of the following options is the amount of gold identical in the two coins? (Pure gold is 24 carat)

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QUESTION ID:21

A lectotype refers to

QUESTION ID:22

A plot with which one of the following axes is drawn to exhibit enzyme inhibition kinetics applying Dixon's plot?

QUESTION ID:23

The maximum frequency of recombination that can occur between two loci is

QUESTION ID:24

Which one of the following routes is responsible for maximum amount of body heat loss in humans at an ambient temperature of 21 ̊C?

QUESTION ID:25

Which one of the following plant pathogens has largest genome size?

QUESTION ID:26

Which one of the following enzymes present in erythrocytes helps bypass the first step of ATP formation in glycolysis?

QUESTION ID:27

The immunoglobulin heavy-chain that is rearranged first and is displayed on the surface of early stages of B-cell development is associated with:

QUESTION ID:28

The trait shown in the above pedigree is

QUESTION ID:29

In Africa "AS" represents a carrier of sickle cell anaemia, where A is the allele for normal haemoglobin and S for sickle cell haemoglobin. If the allele S is maintained at a high frequency in some populations, this represents a case of

QUESTION ID:30

A gene was located on 10p11. This means the gene was located on the

QUESTION ID:31

The 50 km wide Palghat Gap is the only major topographic breach in the Western Ghats. This gap continues as the Ranotsara Gap in the Angavo escarpment. Which country is the Ranotsara Gap located in?

QUESTION ID:32

A plant that produces disc-shaped fruit is crossed with another plant that produces long fruit. All the F1 plants gave disc-shaped fruits. When the

F1 were intercrossed, F2 progeny were produced in the following ratio: 9/16 plants with discshaped fruits; 6/16 plants with spherical fruits

and 1/16 plants having long fruits.

Which one of the following options gives correct genotype of spherical fruits obtained in F2?

QUESTION ID:33

Given below are plots that show changing titres of natural killer cells (NK cells), cytotoxic Tlymphocytes specific to the virus (virus-specific CTLs) and interferon aj {J during a virus infection. (increasing titres)

With respect to changing virus titers, select the plots that represent these factors correctly from the options given below.

QUESTION ID:34

Two populations of squirrels evolved across two regions separated by a large geographic barrier. Over a long period of time these populations are reproductively and geographically isolated from each other. This is an example of

QUESTION ID:35

Which one of the following statements regarding amphibian development is correct?

QUESTION ID:36

A panel of six hybrid cell lines, each containing a different subset of human chromosomes, was examined for the presence of the gene product as shown below

The gene which codes for the given gene product is located on which chromosome?

QUESTION ID:37

In mammals, the primary circadian clock is located in which of the following parts of the brain?

QUESTION ID:38

In the enzyme-linked antibody used in ELISA, the interaction between the enzyme and antibody is stabilized by

QUESTION ID:39

Suppression of VPE (Vascular Enzymes) gene expression in benthamiana plants will NOT

QUESTION ID:40

Which one of the following systems forms a chemical mediator that is involved in the mechanism of pain during inflammation?

QUESTION ID:41

In which one of the following subcellular organelles is serine synthesized during the oxidative photosynthetic carbon (C2) pathway?

QUESTION ID:42

Spermidine represents which of the following group of compounds:

QUESTION ID:43

Given below are the survivorship curves showing the proportion of individuals surviving over time or age. Three generalised types of curves (a, b

and c) are depicted below. Which of the following represent the correct survivorship

QUESTION ID:44

Which one of the statements given below is INCORRECT?

QUESTION ID:45

The term "abominable mystery" was used by Darwin in the context of origin and diversification of

QUESTION ID:46

Dr. Ralph M. Steinman was awarded Nobel Prize for his discovery on:

QUESTION ID:47

Human polysyndactyly (joining of extra digits) syndrome results from a homozygous mutation at

QUESTION ID:48

If bird song is selected to maximize broadcast range and to minimise degradation, then according to the "Acoustic Adaptation Hypothesis" which of the following combination of features is likely to be shown by birds singing in dense forests?

QUESTION ID:49

If the pyrollidine ring of proline is reduced to a linear form, the new amino acid will have

QUESTION ID:50

The following table lists names of scientists and advances made by them

Which one of the following options correctly matches contents of column A with column B?

QUESTION ID:51

The translocation into which one of the organelles listed below DOES NOT depend on an amino acid sequence as a signal for import?

QUESTION ID:52

Artemisinin and Dhurrin belong to which two respective groups of the plant natural compounds?

QUESTION ID:53

In Agrobacterium mediated transformation, which one of the following approaches is more likely to generate transgenic plants with INCOMPLETE transfer of the passenger gene?

QUESTION ID:54

Genome of an organism was analysed by Cot curve analysis. Highly repeated sequences represented 30% of the total genome fraction. The Cot value of the highly repeated sequence was found to be 0.001 moles nucleotide lit^-1 What would be the actual Cot value (in moles nucleotide lit^-1) of the highly repeated sequence?

QUESTION ID:55

Amongst the following, which one is the most appropriate strategy to sequence and assemble highly repeated regions of a genome?

QUESTION ID:56

Receptor for which one of the following proteins spans the plasma membrane of target cells but DOES NOT contain intrinsic protein kinase activity?

QUESTION ID:57

In Trypanosoma, some of the introns generate Y shaped structure in place of a lariat. Such structure is generated during

QUESTION ID:58

In both males and females, the gonads secrete a polypeptide hormone, called inhibin B, which inhibits

QUESTION ID:59

Autogamy refers to

QUESTION ID:60

Electron transfer from donors such as NADH and FADH2 to 02 occurs in

QUESTION ID:61

Erythromycin is an inhibitor of protein synthesis. It acts by:

QUESTION ID:62

Which one of the following statements regarding double fertilization in plants is correct?

QUESTION ID:63

Which one of the following ensures stable binding of RNA polymerase at the promoter site?

QUESTION ID:64

Sonic hedgehog (Shh) specifies the anterior posterior axis during limb development. Which one of the following statements regarding it is correct?

QUESTION ID:65

Which one of the following conditions will switch on Lac operon in E. coli?

QUESTION ID:66

A student added DMEM culture medium which was pink in colour to growing liver cells. Three days later the medium colour was yellow. This indicated

QUESTION ID:67

Which one of the following statements is correct with reference to ecotones?

QUESTION ID:68

According to Hamilton's rule, 'r' is the coefficient of relatedness between two interacting individuals, 'B' is the benefit to the recipient and 'C' is the cost to the donor. Which of the following relationships will result in an altruistic behaviour?

QUESTION ID:69

Given below is a schematic representation of a Southern blot performed to identify single copy integration events of the T-DNA among six transgenic plants {T1-T6).

Which one of the following options represents potential single copy events?

QUESTION ID:70

A researcher has treated pea leaves with pchloromercuribenzene sulfonic acid {PCMBS), which inactivates plasma membrane transporters. It was observed that phloem loading of sucrose is inhibited. Which one of the following interpretations is correct?

QUESTION ID:71

The major structural characteristic of avian gastrulation is the primitive streak, which becomes the blastopore lips of amniotic embryos. Migration through the primitive streak is controlled by Fgf8. What would happen if the Fgf8 protein, which repels migrating cells away from the streak, is over expressed in the primitive streak?

QUESTION ID:72

Given below are the possible reasons of high probability for extinction of species:

(i) Increased homozygosity of alleles

(ii) Increased heterozygosity of alleles

(iii) Decreasing population sizes

(iv) Increasing demographic stochasticity

(v) Decreasing environmental stochasticity

Which one of the following options represents the correct combination of reasons that can lead to the highest probability of extinction of species?

QUESTION ID:73

Felsenstein zone in a phylogenetic tree refers to a region of tree space where,

QUESTION ID:74

Loss of a large quantity of blood in an individual due to haemorrhage provokes many physiological changes which are compensatory and decompensatory in nature. The following statements describe few compensatory or decompensatory mechanisms operating in this condition.

 A. The peripheral chemoreceptors are stimulated when arterial blood pressure is reduced below 60 mm Hg due to blood loss.

B. The cardiovascular centres in the brain stem become depressed in severe hypotension due to blood loss.

C. The mononuclear phagocytic system becomes depressed during the course of haemorrhagic hypotension.

D. Renin is secreted from juxtaglomerular apparatus in haemorrhagic hypotension.

 E. Considerable quantity of interstitial fluid may be drawn into circulation due to lower hydrostatic pressure in capillaries resulting from blood loss.

 Choose the option describing only the decompensatory mechanisms:

QUESTION ID:75

Given below is a list of natural disturbances.

A. Coral bleaching

B. Rising sea levels

C. Shifts in species distribution

D. Lowering of sea levels

E. Increase in glacial sheets

Which one of the following combinations of disturbances can be attributed to global warming?

QUESTION ID:76

In regulating the quantity of enzyme, its degradation plays a pivotal role. Following statements are made to represent the degradation of enzymes in the 26S proteasome.

A. The active sites of proteolytic subunits face exterior of the proteasome cylinder

B. The active sites of proteolytic subunits face interior of the proteasome cylinder

C. Degrading enzymes are targeted to exterior of proteasome by covalent attachment of one or more molecules of ubiquitin

D. Degrading enzymes are targeted to interior of proteasome by covalent attachment of one or more molecules of ubiquitin

Which one of the following combinations of statements represent correct mode of enzyme degradation?

QUESTION ID:77

Given below are four DNA sequences and a set of forward and reverse primers for PCR amplification

In the absence of any other factors such as (but not restricted to) T m, length, percent GC, etc., which one of the above template-primers combinations would produce an amplified fragment?

QUESTION ID:78

cGMP is produced from GTP by the enzyme guanylate cyclase which exists in soluble and membrane-bound forms. Following statements are made related to signaling molecules that are associated with cGMP signaling cascade.

A. Atrial natriuretic factor causes natriuresis and diuresis by interacting with membrane-bound form of guanylate cyclase.

B. Nitroglycerin causes smooth muscle relaxation and vasodilation by interacting

with soluble form of guanylate cyclase.

C. Nitroprusside causes smooth muscle relaxation and vasodilation by interacting

with membrane-bound form of guanylate cyclase.

D. Atrial natriuretic factor causes natriuresis and diuresis by interacting with soluble form of guanylate cyclase.

Which one of the following combinations is correct?

QUESTION ID:79

Given below are few statements related to DNA replication:

A. Replication in eukaryotic chromosomes from the origin(s) is initiated multiple times in each cell cycle while it is initiated only once in each cell cycle at the origin in bacterial chromosomes

B. Improper reinitiation of replication in a eubacterial chromosome is prevented by hemi-methylation status of the bacterial origin

C. DNA polymerase Ill is the major replication polymerase responsible for de novo synthesis of both leading and lagging strands of DNA in E. coli

D. Rolling circle mode of replication produces multiple units of the original molecule

Which one of the following options represents INCORRECT statement(s)?

QUESTION ID:80

E coli cells were simultaneously infected with two strains of phage A. One strain of A had a mutant host range, is temperature sensitive and known to produce clear plaques (genotype h st c); another strain of A carried the wild type alleles (genotype h+ st+ c+). Progeny phages were collected from the lysed cells and were plated on bacteria. The following numbers of different progeny were obtained: 

What will be the order of the three genes and the map distance between them? 

QUESTION ID:81

Programmed cell death {PCD) plays an important role in development of barley aleurone. The following statements are made with respect to

involvement of various phytohormones and signaling molecules.

A. Gibberellic acid promotes PCD.

B. Abscisic acid postpones PCD.

C. Cyclic GMP signaling postpones PCD.

D. Nitric oxide scavenger delays PCD.

Which one of the following combinations of statements is correct?

QUESTION ID:82

The following statements are made with reference to membrane fusion reactions in vesicle transport catalyzed by transmembrane SNARE proteins.

A. The SNARE transmembrane proteins exist as complementary sets, with v-SNARES on vesicle membranes and t-SNARES on target membranes

B. A v-SNARE is usually composed of 3 proteins and t-SNARE is a single polypeptide cha

C. The v-SNARE and t-SNARE proteins of a pair interact via helical domains possessed by the two proteins, resulting in formation of a stable two-helix bundle

D. Membrane fusion is catalysed by the energy that is freed when the interacting helices wrap around each other to pull the membrane faces together, concurrently squeezing out water molecules from the interface.

Which one of the following combinations represents all correct statements?

QUESTION ID:83

In classical Anfinsen's protein folding experiment the enzymatically active ribonuclease is treated with p-mercaptoethanol and 8 M urea.

Following which, the preparation was

A. dialyzed to remove the p-mercaptoethanol and 8 M urea

B. the sample was completely oxidized in 8M urea after dialysis

C. trace amounts of p-mercaptoethanol was added to the dialysed sample

D. 8M urea was added to the dialyzed sample

Which one of the following steps will lead to regaining of the full enzymatic activity of ribonuclease?

QUESTION ID:84

Given below is a partial coding sequence of a gene:

5'-A ATGGACGCATGTGTCGATGG-3

Which one of the following polypeptides CANNOT be produced by transcription and translation of the above DNA sequence in any of the three possible reading frames?

QUESTION ID:85

According to the classical Lotka-Volterra competition model, which of the following conditions allow for co-existence of two competing species

QUESTION ID:86

Appendix masculina is found in

QUESTION ID:87

An experiment was performed to introduce a transgenic trait in a crop plant by Agrobacterium - mediated transformation using a transgene construct in which the transgene was expressed using the CaMV 35S promoter. It was observed that expression levels of the transgenic protein were very low in all transgenic plants while transgene mRNA levels were high and variable among different plants. Further, different transgenic lines contained different numbers of the T-DNA insert. The following statements were made to explain the above observation:

B. Low expression levels of the transgenic protein in all transgenic plants could be due to codon usage variations between the host plant and the heterologous source of the transgene

C. The coding sequence of the transgene contained sequences that destabilized the transgene mRNA

D. Variation in copy number of T-DNA in different transgenic plants is due to variation in the promoter used to express the transgene. Which one of the following options represents all correct statements?

QUESTION ID:88

In high altitude, a number of compensatory mechanisms operate over a period of time to increase altitude tolerance in humans which is called acclimatization. The following statements propose these compensatory changes:

A. The initial increase of ventilation is relatively small in high altitude but the ventilation steadily increases over next few days.

B. Red blood cell 2, 3-DPG is increased.

C. The blood pH becomes more alkaline.

D. The oxygen dissociation curve is shifted to the left.

E. The pH of cerebrospinal fluid is further increased.

Choose the option with both INCORRECT statements:

QUESTION ID:89

The following statements are being made about the archaeal cell wall/membrane:

A. Archaeal cell walls could stain Gram +ve or Gram -ve depending on the genus

B. Archaea are characterized by Gram +ve staining of the cell wall

C. Archaeal cell walls are susceptible to degradation by lysozyme

D. Archaeal cell membranes possess branch chain hydrocarbons linked to glycerol by ether links

Which of the following combinations of statements represents all correct statements?

QUESTION ID:90

A researcher intends to stimulate neurons via glutamate receptors in medial septum of an experimental animal. The following apparatus/

instruments are available in the laboratory:

A. Stereotaxic apparatus

B. Slow perfusion pump

C. Microcannula

D. Radiofrequency lesion maker

E. Electrical stimulator

F. Nichrome coated bipolar steel electrode

Which one of the following options contains all the correct items required for the experiment?

QUESTION ID:91

QUESTION ID:92

The figure below shows a gene duplication event followed by a divergence event in species 1 and 2.

Based on the details given above determine what is represented by A and B

QUESTION ID:93

In the two graphs given below, what do a, b and c refer to

QUESTION ID:94

Expression of gene 'A' is a regulated by Mg2 + The expression of gene 'A' in untreated (UN) and cells treated with Mg2 + (T) was analysed by Northern hybridization (N) and Western blotting (W). A similar exercise was done for a mutant (Mut) which was isolated with a 6 bp deletion in 5'UTR of the transcript of gene 'A'. The following are summary of four possible results that are hypothesized to be obtained

UN = Untreated Cells, WT = Wild type cells, T = Cells treated with Mg2 +, Mut = Cell with mutation

in gene A, N = Northern hybridization, W = Western blotting

If the regulation of gene 'A' expression is controlled ONLY at the level of translation, which of the above profile/s are possible correct representation of the experimental results.

QUESTION ID:95

The electrical response of the afferent nerve terminal in a Pacinian corpuscle (PC), after application of different grades of pressure, are proposed in the following statements:

A. A non-propagated depolarizing potential or receptor potential is elicited when small magnitude of pressure is applied to PC.

B. The magnitude of receptor potential is increased as the pressure to PC is increased.

C. An action potential is generated when receptor potential attains a critical value.

D. The receptor potential shows all-or-none response.

E. The receptor potential is not a graded potential.

Choose the option with both INCORRECT statements:

QUESTION ID:96

PR proteins play important role during plantpathogen interactions. Column X represents some of the PR family proteins and column Y represents their main properties. 

The correct match of column X with the property in column Y is

QUESTION ID:97

Three strains of pathogenic bacteria were found to express proteins mimicking human proteins associated with complement pathway. Bacterium 'X' expressed on its surface proteins mimicking Decay Accelerating Factor {OAF) and Complement Receptor 1 (CR1). Bacterium 'Y' secreted a protein that mimicked protein of humans and bacterium Z secreted protein that mimicked Factor I activity. Given below are statements on the possible effect of complement activation on these pathogenic bacteria. Select the INCORRECT statement

QUESTION ID:98

The continued expression of engrailed and wingless is maintained by interactions between the Engrailed- and Wingless-expressing cells. The following statements are given towards the initiation of the cascade of events that occur for this interaction:

B. The wingless gene is expressed in those cells that contain high concentration of either Even skipped or Fushi tarazu.

C. Wingless is a secreted protein, diffuses to the surrounding, binds with the Frizzled and Lrpo receptor proteins and activates engrailed gene via Armadillo.

 D. Hedgehog protein activates the transcription of engrailed and also activates its own transcription.

E. Hedgehog protein diffuses from cells and binds to Patched receptor on neighbouring cells and enables transcription of wingless gene.

Which combination of above statements correctly represent the maintenance of engrailed and wingless expression?

QUESTION ID:99

For an exponentially growing culture of bacteria where No is the initial population number and N t is the population number at time t, the mean growth rate constant (K) is expressed as

QUESTION ID:100

The following information refers to ecological interactions.

Which one of the following options represents the correct match between column X and column Y?

QUESTION ID:101

In C. elegans, activation of the CED-3 and CED-4 proteins are essential for the apoptosis pathway. In addition, gain-of-function mutations in the ced-9 gene cause its protein to be made in cells that would normally die, resulting in survival of those cells. Given these facts, which one of the following diagrams correctly represents a cell death pathway? 

QUESTION ID:102

The three domain classification of life proposed by Carl Woese divides life forms on the basis of

QUESTION ID:103

Given below are statements related to various molecular techniques

A. During molecular cloning of DNA fragments, a vector and insert molecule digested with two different enzymes can never be ligated with each other.

B. Only 3'~5' exonucleases and not 5'~3'exonucleases can be used for digesting nucleic acids to generate blunt-ended fragments for cloning.

C. In Sanger's dideoxy sequencing method, each reaction consists of a mixture of three dNTPs and one ddNTP.

D. Self-ligation of a vector with compatible ends can be prevented by treatment with alkaline phosphatase.

Which one of the following options represents a combination of correct statements?

QUESTION ID:104

The NPR1 (non-expresser of pathogenesisrelated genes 1) and two SA receptors (NPR3 and NPR4) are known to play important role in SA mediated plant defense. The following statements were made regarding their role in infected and non-infected tissues of the plants:

A. In the infected tissue, SA binds to NPR3 and induces degradation of NPR1 to promote cell death.

B. In the infected tissue, SA binds to NPR4 and blocks the degradation of NPR1 to promote cell death.

C. In the non-infected tissue, SA binds to NPR4 and blocks the degradation of NPR1 to favour cell survival.

D. In the non-infected tissue, SA binds to NPR3 and promotes degradation of NPR1 to favour cell survival.

Which one of the following combination of statements is correct?

QUESTION ID:105

The statements given below refer to the lambda phage.

A. Clear plaques are formed in Q mutants

B. No plaques are formed in nut mutants

C. Clear plaques are formed in ell mutants

D. Turbid plaques are formed in integrase mutants

E. Clear plaques are formed in P mutants

F. No plaques are formed inc/ mutants

Which of the following combination of statements is correct?

QUESTION ID:106

Distance matrix of five species A to E is given below. 

Which one of the following topologies represents the accurate species relationships among species A to E if UPGMA clustering method is used for the given data?

QUESTION ID:107

Pathogens continuously evolve strategies to evade host immune responses. For each of the following evasion strategies (listed in column X) match the pathogen (listed in column Y) which adopts it:

Choose the correct match

QUESTION ID:108

Creationism is rejected by evolutionary biologists because

QUESTION ID:109

Given below are proposed analogous structures among organisms.

A. wings of birds and bats

B. wings of bats and tetrapod digits

C. tendrils of vitis and tendrils of pumpkin

D. tubers of potatoes and sweet potatoes

E. fins of fish and flippers of a whale

Which one of the following options correctly states the analogous structures?

QUESTION ID:110

A large patch of forested area was devastated by raging fires. After some years, the area was found to recover its species. Which one of the following options best describes the process of re-establishment in the area?

QUESTION ID:111

Given below are four sentences with blanks (labelled X, Y, Z and L). A. RNA Poll transcribes X B. miRNA genes are transcribed by __ v __ . C. The RNA polymerase found only in plants is z D. tasiRNAs are synthesized by L Which one of the following options would present the combination of all terms (in the order X, Y, Z and L) to complete the above sentences correctly

QUESTION ID:112

To study the effect of temperature on seed germination, 16 seeds of a plant species were selected for an experiment. A total of four temperature treatments were provided to sets of four seeds to study the onset of germination.

What would be the within, between and total degrees of freedom, respectively, in an analysis of variance?

QUESTION ID:113

Several marine organism release their gametes into the environment, where sperm attraction and subsequent events lead to successful fertilization. With reference to sea urchins, which one of the following statements is NOT true?

QUESTION ID:114

Kallmann syndrome generally exhibits gonadal dysfunctions in males. Following statements are made relating to such males.

A. They mostly suffer from hypergonadism

B. They mostly suffer from hypogonadism

C. They have higher level of circulating gonadotropins

D. They have lower level of circulating gonadotropins

Which one of the following combinations of statements is correct?

QUESTION ID:115

Calvin-Benson cycle is divided into three phases, namely carboxylation, reduction and regeneration. The following statements are related to the three phases of Calvin-Benson cycle:

A. The product of light reaction, ATP and NADPH is utilized in the carboxylation phase.

B. Six molecules of 3-phosphoglycerate is converted into six molecules of glyceraldehyde 3-phosphate in the reduction phase.

C. The action of aldolase enzyme for the production of fructose 1, 6-bisphosphate takes place in reduction phase.

D. Formation of seven carbon compound, sedoheptulose-7-phosphate takes place in the regeneration phase.

Which one of the following combinations is correct?

QUESTION ID:116

Which one of the following statements is true with regard to drug metabolism?

QUESTION ID:117

Curled wing (cu), ebony body colour( e) and sepia eye (se) are three recessive mutations that occur in fruit flies. The loci for these mutations have been mapped and they are separated by the following hypothetical map distances:

The interference between these genes is 0.4. A mutant cu e se fly was crossed with a homozygous wild type fly. The resulting F1 females were test crossed that produced 1800 progeny. What number of flies in each phenotype class is likely to be obtained in the progeny of the test cross?

QUESTION ID:118

In some sheep, horns are produced by an autosomal allele, 'H', that is dominant in males and recessive in females. WW individuals are hornless. A horned female is crossed with a hornless male. One of the resulting F1 females is crossed with a hornless male. What proportion of the male and female progeny of F1 will have horns?

QUESTION ID:119

The following statements are made with reference to the replication of DNA.

A. The eukaryotic counterpart of the bacterial (Jclamp protein is proliferating cell nuclear antigen (PCNA)

B. Mutation inactivating one of the subunits of the Mcm 2-7 complex negatively affects the initiation of DNA replication in eukaryotes, but has no effect on elongation of the replication fork

C. All DNA polymerases responsible for replicating the eukaryotic genome catalyze DNA chain extension in a DNA templatedependent manner.

D. The FENI protein plays a role in the synthesis of the lagging strand during DNA replication as well as in base excision repair

Which one of the following options represents INCORRECT statement(s)?

QUESTION ID:120

The figure below represents a profile of DNA markers in two parents {P1 and P2), progeny {Fl) from a cross between P1 and P2 and that of gametes produced from Fl. Eight different patterns {DH1 to DHS) were observed in case of gametes. The numbers below, DH1 to DHS indicate the number of individuals observed in each case 

Based on the above observations, the following statements were made:

A. Markers 'b' and 'f' are likely to be allelic in nature

B. Markers 'c' and 'd' are linked in trans with a map distance of 24 eM

C. Marker 'b' assorts independently from marker  'c'

Which one of the following have a combination of all correct statements?

QUESTION ID:121

The following statements are related to transcription in bacterial eukaryotes.

A. During concurrent promoter sequence recognition and melting, melting commences

with base flipping where two bases are flipped out into pockets of the primary sigma factor

B. Binding of a-amanitin to RNA polymerase II permits entry of nucleotides into RNA pol II active site and synthesis of RNA, but prevents translocation

C. RNA polymerase I can use upstream promoters with 3 consensus sequences, as well as internal promoters having a bipartite structure

D. FACT is associated with RNA polymerase during transcriptional elongation and helps displace histone octomers during transcription

Which of the following combinations of statements represents all correct statements?

QUESTION ID:122

For a given immunological application [column X], select the type of antibody [column Y] that should be used·

Choose the option with correct matches between terms of Columns X and Y.

QUESTION ID:123

Following are certain statements regarding nitrogen uptake and assimilation by plants:

A. Plant roots can take up nitrogen in the form of NO₃ or NH₄

B. NH4 taken up by plants can be directly assimilated into amino acids.

C. Amino acids are synthesized exclusively in plastids and chloroplast of roots and leaves, respectively.

D. N03 can be stored in vacuole of both, roots and leaves.

Which one of the following combinations is correct?

QUESTION ID:124

The following statements were made regarding the role of protein modifications

A. Attachment of acetyl groups to the amino termini of proteins makes it more resistant to degradation.

B. Attachment of hydroxyl groups to proline residues stabilizes fibres of newly synthesized collagen

C. Addition of sugars (glycosylation) makes protein more hydrophilic enabling protein protein interactions

D. Addition of sugars (glycosylation) makes protein more hydrophobic enabling protein folding

Which one of the following combinations represents all correct statements?

QUESTION ID:125

The table below lists cell cycle regulatory proteins and their known functions

Which one of the following options represents the correct match between cell cycle regulatory proteins with their known functions?

QUESTION ID:126

Suresh was bitten by a poisonous snake and was immediately treated with anti-venom human immunoglobulin and was saved. A year later he was bitten by the same type of snake second time. Predict his response to the venom from second bite from the following:

QUESTION ID:127

The following statements were made to describe the role of Gibbs free energy

A. Reaction can take place spontaneously if dG is negative

B. Reaction can take place spontaneously if dG is positive

C. dG provides no information about the rate of a reaction

D. dG estimation provides the rate of a reaction.

Which one of the following represents all correct statements?

QUESTION ID:128

Dreisch performed the "pressure plate experiment" to alter the distribution of nuclei in a 8-cell sea urchin embryo. He obtained normal larvae from these embryos. Following possible conclusions could be drawn:

A. Prospective potency of the blastomeres is less than the actual prospective fate.

B. Sea urchin embryo is a "harmonious equipotential system" implying that cell interaction is critical for normal development.

C. Prospective potency of the blastomere is greater than the actual prospective fate.

D. Prospective potency of the blastomere is equal to the prospective fate.

Which one of the following combinations of statements represents the correct inference from the experiment?

QUESTION ID:129

The discharge patterns in a single afferent nerve fibre from carotid sinus at various levels of mean arterial pressure (MAP) are plotted against changes in aortic pressure with time in the following figure:

The following statements were proposed from the above figure:

A. Baroreceptors are more sensitive to phasic change of aortic pressure at normal MAP

B. The baroreceptor firing rate is reduced at lower MAP than in normal MAP

C. The phasic change in baroreceptor fibre is less prominent at lower MAP

D. A burst of action potentials appear in a single baroreceptor fibre during diastole at normal MAP

E. The discharge of baroreceptors even extends to systole at higher MAP

Choose the option with both CORRECT statements:

QUESTION ID:130

Co-existence of several species of birds in an area is possible under the following conditions

QUESTION ID:131

An antigen was injected into a mouse. Macrophages and antigen primed T H cells were isolated from this mouse to perform the following in vitro experiments:

B. Macrophages were treated with paraformaldehyde first and then treated with the antigen for an hour. These macrophages were then incubated with T H cells.

C. Macrophages were treated with paraformaldehyde first then treated with the digested (proteolytically cleaved) antigen for an hour. These macrophages were then incubated with T H cells.

D. Macrophages were treated with the antigen for an hour and then treated with paraformaldehyde. These macrophages were then incubated with T H cells.

Which of the above experiments would lead to T H cells proliferation?

QUESTION ID:132

A researcher developed a mutant of Arabidopsis plant where the function of SLEEPY 1 (SLY1) containing SCF complex has been disrupted. Which one of the following statements is INCORRECT in the developed mutant in relation to gibberellic acid (GA) signal transduction?

QUESTION ID:133

Given below is a list of plant species and reproductive forms·

Which one of the following options correctly matches all the given plant species with their reproductive forms?

QUESTION ID:134

The mammalian protein HP1 plays a major role in heterochromati-nization and silencing. The following mutations are proposed to negatively impact HP1 function.

A. Mutation inactivating the deacetylase that targets H3K14Ac

B. Mutation inactivating HP1 bromo-domain

C. Mutation inactivating HP1 chromo-domain

D. Mutation inactivating the KMTlA methyltransferase whose target site is H3K9

Which one of the following combinations represents all correct statements?

QUESTION ID:135

Body weight of rabbits is determined by pairs of alleles at two loci, 'a' and 'b', that are additive and equal in their effects. Rabbits with genotype a- a- b- b- have average 1 kg body weight, whereas individuals with genotype a+ a+ b+ b+ have animals that average 3.4 kg in weight. A male rabbit with a- a- b- b- is crossed with a female of genotype a+ a+ b+ b+. What will be predicted average weight of F1 progeny of this cross?

QUESTION ID:136

Following are the statements which explain why patients with a-linked hyper-lgM syndrome express normal genes for other antibody subtypes but fail to produce lgG, lgA, or lgE:

A. CD40 expressed on B cells is defective

B. CD40L mediates binding of B-cells to T-cells and sends co-stimulatory signals to the B-cells for class switching

C. Without CD40 on macrophage, class switching does not occur

D. CD40L mediates binding of B-cells to macrophages and sends co-stimulatory signals to the B-cells for class switching.

Select the option with correct combination.

QUESTION ID:137

Dark grown Arabidopsis seedlings when exposed to ethylene gas shows typical triple response.

Following are certain statements regarding the triple response:

A. A dominant ethylene receptor mutant will not show triple response in the presence of ethylene.

B. Tightening of apical hook is one of the features of triple response.

C. Loss of function of multiple receptors will show triple response even in the absence of ethylene.

D. Increase in hypocotyl length is a feature of triple response.

Which one of the following combinations is correct?

QUESTION ID:138

Gene therapy is a promising tool for addressing several diseases in humans. With respect to the above, which one of the following statements is FALSE?

QUESTION ID:139

Select the correct statement. The bark of a woody plant is collectively made up of the following tissues:

QUESTION ID:140

A field biologist is sampling tree species in a forest area to estimate tree diversity. What method can be employed to decide if his sampling effort is adequate to estimate the tree diversity in the area?

QUESTION ID:141

Given below are some terms in column A and their corresponding properties/related terms in column B 

Which one of the following options represents the most appropriate match between all terms of column A and B?

QUESTION ID:142

The following statements describe the propensity and role of amino acids in the secondary structure of proteins

A. Alanine has a high frequency of occurrence in a-helices

B. Proline has a high frequency of occurrence in a-helices

C. The x 1 does not affect the helix propensity of serine, threonine and valine

D. Peptide bonds involving 'N' of proline may display cis-trans isomerism

Choose the correct combination.

QUESTION ID:143

Given below are a few statements related to biological principles and/or techniques:

A. Genetic diversity plays an important role in the identification of combiners for heterosis breeding

B. Genotyping by sequencing (GBS) can be used to identify allelic diversity but is not useful for construction of linkage maps.

C. Genome editing by sequence specific nucleases (SSNS) in the presence of guide RNAs would result in NHEJ-mediated knock outs and loss of function mutations.

D. In a comparison of synteny and colinearity between diploid and polyploid plant genomes, colinearity is high but synteny is low.

Which one of the following options represents all correct statements?

QUESTION ID:144

A species of plant (species 1) is diploid (2n = 6) with chromosomes AABBCC and a related species (species 2) is also diploid {2n = 4) with chromosomes PPQQ. The following statements were given by students regarding the chromosome numbers involving these plant species:

A. Autotriploid of species 1 will have 12 chromosomes

B. Allotetraploid involving species 1 and 2 will have 16 chromosomes

C. A monosomy in species 1 will generate 5 chromosomes

D. A double trisomy in species 1 will generate 8 chromosomes

E. A nullisomy in species 2 will generate 2 chromosomes

The combination of statements with all correct answers is: