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QUESTION ID:1
The Cre-LoxP system was used to knock-out the p53 gene from the mice lungs. An immunoblot analysis was carried out as shown below
The following assumptions were made
A. The LoxP system did not work since the recombinase was not functional.
B. The Lox P sites were introduced under a promoter specific for lungs.
C. The tissue-specified promoter selected was of the prostate gland.
D. The mice died because of being knocked out of p53.
E. The knocked-out mice developed mutagen-induced tumours in their prostate gland more rapidly than in their lungs
Which one of the following is correct combination of above assumption?