QUESTION ID:1
Aspartic acid (Asp) is specified by the codon GAU and GAC. After mutation, Asp is changed to Alanine represented by GCX, where X may be A, U, C and G. The reversion of the mutation could only be done with reactive oxygen species. The nature of mutation is considered to be
QUESTION ID:2
A cross is made between two plants with white flowers. All the F1 progeny had red coloured flower. This is because of
QUESTION ID:3
Cladistic classification is based on
QUESTION ID:4
Tautonym is an informal taxonomic designation used for animals referring to
QUESTION ID:5
A marine biologist dug up a small animal from the ocean floor. The animal was uniformly segmented with short, stiff appendages and soft, flexible skin. It had a complete digestive system and an open circulatory system but no exoskeleton. Based on this description, the animal appears to be a
QUESTION ID:6
Which of these programs is used to conserve a species facing extinction?
QUESTION ID:7
A grasshopper population is being assessed by capture-mark-release-recapture method. On the first day, 100 grasshoppers were captured from a given area in 1 hour time, marked and released. On the next day during recapture, 10 marked and 90 unmarked grasshoppers could be found in the same time period from same area. What will be the estimated population size in the given area?
QUESTION ID:8
Free-living nitrogen fixers can survive in different ecological niches. IdentifY the incorrect combination from the following list:
QUESTION ID:9
A plot of soil contaminated with diesel oil was inoculated with oyster mushrooms. After 4 weeks, more than 95% of the polycyclic aromatic hydrocarbons had been reduced to non-toxic compounds. This process is called
QUESTION ID:10
In pre-industrial period in England, peppered moths had light coloration which effectively camouflaged' them against light coloured trees and lichens. During industrial revolution, many lichens died out and trees became blackened by soot from factories and interestingly, dark coloured moths were predominantly seen. This happened due to
QUESTION ID:11
The speciation in which a population splits into two geographically isolated populations experience dissimilar selective pressure and genetic drift is known as
QUESTION ID:12
Evolution of multi-gene family occurs by
QUESTION ID:13
One aims to find out the role of a gene product in macrophages by using a transgenic mouse expressing the genes under a promoter. Which of the following is the most appropriate promoter?
QUESTION ID:14
Which of the following genes was engineered in the "Flavr Savr" transgenic tomato variety?
QUESTION ID:15
For developing transgenic mice, embryonic stem cells are engineered to express the transgene. These cells are selected by
QUESTION ID:16
Microbial leaching involves the process of dissolution of metals from ore breaking rocks using microorganisms. Which one of the following bacteria helps in leaching copper from its ore?
QUESTION ID:17
Molar absorption coefficient of phenylalanine is 200 M-1cm-1 at 257 nm. What concentration (g/L) of this amino acid will give an absorption of 1 in a cell of 0.5-cm path length at 257nm?
QUESTION ID:18
Which of the following atomic nuclei cannot be probed by nuclear magnetic resonance spectroscopy?
QUESTION ID:19
69. t½ of an irreversible first order reaction, S→P is 1 hour. The time (in hours) required to reach 75% completion is

QUESTION ID:20
In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?
QUESTION ID:21
The amino acid alanine has high propensity to occur in helical conformation. The Circular dichroism spectrum of an equimolar mixture of two 20-residue peptides, one composed of only L-alanine and the other only D-alanine is recorded in the region of 185-250 nm. Which one of the following will be observed?
QUESTION ID:22
The following small peptide substrates are used for determining elastase activity and the following data have been recorded
The arrow indicates the Cleavage site. From the above observations, it appears that:
(A) PAPAF is digested most rapidly.
(B) PAPAG is digested most rapidly.
(C) A hydrophobic residue at the C- terminus seems to be favored. .
(D) A smaller residue at the C-terminus seems to be favored.
(E) Elastase always requires a smaller residue at the Nterminus of the cleavage site.
Which of the following is true?

QUESTION ID:23
The apparent pH of a fluid is 7.45, where bicarbonate buffer is involved for maintaining its pH. Values of pKa of carbonic acid are 6.15 and 10.45. The molar ratio of [conjugate base]:[acid) is
(Hint: antilog 1.3 = 20.0, and antilog 10.3 = 1000)
QUESTION ID:24
A segment of B-DNA encodes an enzyme of molecular mass 50 kD. The estimated length of this segment in μm would be
QUESTION ID:25
In order to determine the primary structure of an octapeptide, amino acid composition was detennined by acid hydrolysis (A). The intact oligopeptide was treated with carboxypeptidase (B), chymotrypsin (C), trypsin (D) and CNBr (E). The peptides were separated in each
case and acid hydrolysis was carried out for B - E. Following results were obtained (the brackets represent mixtures of amino acids in each fragment):
(A) (2Ala, Arg, Lys, Met, Phe, 2Ser)
(B) (Ala, Arg, Lys, Met, Phe, 2Ser) and Ala
(C) (Ala, Arg, Phe, Ser), (Ala, Lys, Met, Ser)
(D) (Ala, Arg), (Lys, Phe, Ser), (Ala, Met, Ser)
(E) (Ala, Arg, Lys, Met, Phe, Ser), (Ala, Ser)
Which one is the correct sequence of the presence of this protein upon oIigopeptide?
QUESTION ID:26
You are following the intracellular sorting of an integral plasma membrane protein in a living cell, in culture. You have decided to probe this protein by metabolic labeling technique with 35S-methionine (pulsechase technique). After one cycle of division, the cells were treated with a potent inhibitor of protein biosynthesis and processed for subcellular fractionation. In which of the following fractions will you expect the immunoprecipitation with a specific antibody?
QUESTION ID:27
The principal pathway for transport of lysosomal hydrolases from the trans Golgi network (pH 6.6) to the late endosomes (pH 6.0) and the recycling of M6P (mannose 6 phosphate) receptors back to the Goigi depends on the pH difference between those two compartments. From what you know about M6P receptor binding and recycling and the pathways for delivery of material to lysosomes, predict what would happen if the pH in late endosomes was raised to 6.6?
QUESTION ID:28
The diploid genome of a species comprises 6.4 x 10^9 bp and fits into a nucleus that is 6 μm in diameter. If base pairs' occur at intervals of 0.34 nm along the DNA helix, what is the total length of DNA in a testing cell?
QUESTION ID:29
Phosphorylation of serines as well as methylation and acetylation of Iysines in histone tails affect the stability of chromatin structure above the nucleosome level and have important consequences for gene expression. The resulting changes in charge are expected to affect the ability of the tails to interact with DNA because
QUESTION ID:30
Cell that grow and divide in a medium containing radioactive thymidine covalently incorporate the thymidine into their DNA during S phase. Consider a simple experiment in which cells are labelled by a brief (30 minutes) exposure to radioactive thymidine. The medium is then replaced with one containing unlabeled thymidine and the cells grow and divide for some additional time. At different time points after replacement of the medium, cells are examined under a microscope.Cells in mitosis are easy to recognize by their condensed chromosomes and the fraction of mitotic cells that have radioactive DNA can be estimated by autoradiography and plotted as a function of time after the thymidine labeling as in the figure below The rise and fall of the curve is because:

QUESTION ID:31
A rapidly growing bacterial species such as E. coli exhibits a typical phase of growth cycle in liquid nutrient broth ( Iag phase → log phase → stationary phase → death phase). If a bacterial culture has starting density of 103 cells/ml has a lag time of 10 minutes and a generation time of 10 minutes, what will the cell density be at (cells/m1) 30 minutes?

QUESTION ID:32
In order to study the role of telomeres in DNA replication, genetically engineered mice were prepared, where the gene for telomerase RNA was knocked out. When cells from these knock out mice were taken and cultured in vitro, they proliferated even after 100 cell divisions which is quite unlikely in the case of human cells. Which of the following is the correct reason?
QUESTION ID:33
You are working with an in vitro eukaryotic transcription system, which produced both capped and uncapped mRNAs. You incubated these mRNAs with mammalian cell nuclear extract and then quantified the different products as shown below. Which of the following graphs correctly represents the expected result?

QUESTION ID:34
A non-enzymatic viral protein X was found to be inducing a cellular gene promoter activity. Although no in vitro DNA binding activity could be identified with X protein, it was found to be co-recruited on the cellular promoter along with a cellular transcription factor in vivo. Which one of the following statements seems to be the best interpretation of the above findings?
QUESTION ID:35
During elongation step or protein synthesis, translocation moves the mRNA and the peptidyl t-RNA by one codon through the ribosome. Translocation in E. coli involves GTP and EF-G. However, in vitro translocation can take place independent of GTP and EFG. Based on these observations, the following hypotheses can be made:
(A) The molecular mechanism of translocation in vitro is completely different from that in vivo.
(B) Translocation activity is independent of GTP hydrolysis.
(C) Translocation activity is completely dependent on GTP and EF-G.
(D) Translocation activity is inherent in ribosomes, however, the rate of translocation in vivo is enhanced significantly in presence of GTP and EF-G
Which one of the following combinations is correct?
QUESTION ID:36
DNA methylation plays an important role in transcription regulation in vertebrates. There is an inverse correlation between the level of DNA methylation in the vicinity of a gene and its transcription rate, whereas there is a direct correlation between histone acetylation and increased transcription. β- thalassemia is a common genetic impairment of hemoglobin β-chain synthesis in humans. If these patients can synthesize hemoglobin-F instead of hemoglobin chain in its place, they would be notably benefited. Administration of 5-azacytidine to thalassemia patients increases hemoglobin-F level in erythrocytes and thus benefit the patients
Which one of the following statements about 5- azacytidine is NOT correct?
QUESTION ID:37
In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of cAMP, which is a second messenger, will lead to
QUESTION ID:38
Binding of a ligand to a cell-surface receptor activates an intracellular signal transduction pathway through the sequential activation of four proteil1 kinases. In the human cell line A, these kinases are held in a signaling complex by a scaffolding 'protein whereas in another cell line B/these kinases are freely diffusible. Which one of the following possibilities do you think is NOT correct?
QUESTION ID:39
Mouse erythroleukemia (MEL) cells are used as an in vitro cell culture model for understanding erythropoiesis. The ceIls are arrested at the stage of proerythroblast due to transformation. These cells could be induced by heme to differentiate further so as to synthesize hemoglobin. The most probable molecular mechanism for this could be that heme may suppress and/or downregulate an endogenous heme-regulated inhibitor (HRI) kinase, an inhibitor of globin synthesis. This downregulation in turn promotes differentiation. To validate this hypothesis which of the following approaches is NOT appropriate?
QUESTION ID:40
Cells undergo apoptosis by two distinct and interconnected pathways: extrinsic and intrinsic. Extrinsic pathway is activated by extracellular ligand binding to cell surface death receptors. Whenever an apoptotic stimulus activates intrinsic pathway, the pro-apoptotic Bax and Bak proteins become -activated and induce the release of cytochrome C from mitochondria leading to caspase cascade activation resulting in apoptosis. In cell A, cytochrome C is introduced by microinjection whereas in cell B, cytochrome C is introduced by microinjection but Bax and Bak are inactivated. What will be the most appropriate apoptotic response type in both cells?

QUESTION ID:41
Dendritic cells (DC) from BALB/c mice were treated with IL-10 or with IFN-γ. Similarly, dendritic cells from β2-microglobulin-deficient mice were also treated with IL-10 or with IFN- γ. These cells were co-cultured with CD8+ T cells from hen egg lysozyme (HEL)-specific T cell receptor transgenic mice in presence of the HEL peptide. Five days later, CD8+ T cells were assayed for target cell lysis. Which one of the following combinations will have the highest target cytotoxicity?
QUESTION ID:42
Polyspermy results when two or more sperms fertilize an egg. It is usually lethal since it results in blastomeres with different numbers and types of chromosomes. Many species therefore, have two blocks to polyspermy: the fast block and the slow block. In the case of sea urchins:
(A) the fast block is immediate and causes the egg membrane resting potential' to rise which does not allow the sperm to fuse with the egg and is mediated by an influx of sodium ions.
(B) the fast block is immediate and causes the egg membrane resting potential to rise which does not allow the sperm to fuse with the egg and is mediated by an efllux of sodium ions.
(C) the slow block or cortical granule reaction is mediated by calcium ions
(D) the slow block or cortical granule reaction is mediated by potassium ions.
Which of the above statements are true?
QUESTION ID:43
In an experiment, the cells that would normally become the middle segment of a Drosophila leg were removed from the leg forming area of the larva and were placed in the tip of the fly's antenna. Based on the "French flag" analogy for the operation of a gradient of positional information, which of the following statements is true?
QUESTION ID:44
Which of the inferences (A-D) given below would you draw from the following tissue transplantation experiments performed with the early and late gastrula stages of the newt?
(A) Cells of early newt gastrula exhibit conditional development.
(B) Cells of early newt gastrula exhibit autonomous development
(C) Cells of late newt gastrula exhibit conditional development.
(D) Cells of late gastrula exhibit autonomous development.
The correct inferences are:

QUESTION ID:45
Segmentation genes in Drossophila are divided into three groups (gap, pair rule and segment polarity) based on their mutant phenotype. Below are some of the major genes expressed in a sequential ,manner (with respect to the groups) affecting segmentation pattern. Which of the above sequence(s) of genes expressed from early to late embryo is/are correct?
(A) hairy → paired → tailless → patched
(B) hunchback → even-skipped → fushi tarazu → wingless
(C) odd-skipped → giant → paired → wingless
(D) tailless → hairy →fushi tarazu → gooseberry

QUESTION ID:46
Human chorionic gonadotropin (hCG) is known to facilitate attachment of blastocyst to uterus. In women with mutation in hCG gene, biologically inactive hCG was formed but implantation occurred. When heG was immune-neutralized in the uterus of normal woman, implantation failed. This suggests that for implantation in humans:
QUESTION ID:47
During reproductive development in plants:
(A) male and female gametes are produced as a result of two mitotic divisions after meiosis
(B) vegetative cells in pollen contribute to pollen development
(C) antipodal provide nourishment to developing embryo
(D) Pollen tube ruptures and releases both the male gametes in one of the degenerated synergids
Which of the above statement are true?
QUESTION ID:48
During fertilization "in mammals, sperm-egg interaction is mediated by zona pellucida (ZP) membrane proteins and their receptors present in sperm membrane. ZP3 has been identified to be the principle ZP protein whose post-translational modification is important for sperm - egg interaction. In a competitive inhibition assay the sperm is saturated with either active ZP3 or its modified forms, before studying sperm-egg-interaction. Which of the following experiments will NOT inhibit sperm-egg-interaction
QUESTION ID:49
If an Arabidopsis plant, mutated in lycopene biosynthetic pathway is grown in sunny tropical climate in the presence of oxygen:
QUESTION ID:50
According to the current model of alternative oxidase regulation, the following factors cause induction of alternative oxidase:
(A) significant increase in the ubiquitin pool in the cytosol.
(B) presence of α-keto acids (like pyruvate and glyoxylate).
(C) cold stress.
(D) increase in cytosolic ATP concentration.
Which one of the following combinations of above statements is true?
QUESTION ID:51
The oxidative pentose phosphate pathway provides the reducing equivalents for nitrite reduction in plastids (Ieucoplasts) of non-green tissues. Which one of the following statements would be correct for the above mentioned pathway?
QUESTION ID:52
Perception of blue light in plants causes
QUESTION ID:53
Following are few statements regarding water potential of soil.
(A) The osmotic potential (ψs) of soil water is generally negligible, except in saline soils.
(B) The osmotic potential (ψs) of saline soil is always more than zero.
(C) In dry soils the hydrostatic pressure (ψp) of soil water potential is always positive.
(D) Gravitational potential (ψg) of soil water is always proportional to height of the tree.
Which one of the following combinations of above statements is true?
QUESTION ID:54
Which One of the following pairs of precursor amino acid and alkaloid is correct?
QUESTION ID:55
Typical morphological defects are routinely used in genetic screens to identify novel genes in signal transduction pathways. Which one of the following morphology has been used to decipher the ethylene signaling pathways?
QUESTION ID:56
In bone marrow, stem cells are committed to different lineages. Factors that stimulate colonies of these different lineages are interleukin-3 (multi-CSF), granulocyte- macrophage colony stimulating factor (GMCSF) and granulocyte or macrophage colony- stimulating factor (G-CSF or M-CSF). In a mouse deficient in GM-CSF the number of hematopoietic cells will be altered. Which one of the following is correct?
QUESTION ID:57
An individual was suffering from digestive complications. It was observed that the individual had dehydrated gastrointestinal tract. When an advanced investigation was done, the person was found to have defects in the following:
(A) cystic fibrosis transmembrane conductance regulator protein.
(B) glucose transporter protein.
(C) Na + /K+ ATPase
(D) Ca2+ATPase
Which of the above could be the cause for such a digestive disorder?
QUESTION ID:58
The action potential was recorded intracellularly from a squid giant axon bathed in two types of fluid such as sea water and artificial sea water having lower concentration of sodium ions while maintaining the same osmotic pressure with choline chloride. The nature of action potential was different in the two bathing fluids. Which of the following results is most likely?
QUESTION ID:59
Three forms of dextrans namely neutral, polyanionic and polycationic having different molecular radii were injected separately in three groups of rats. The concentrations of dextrans in glomerular filtrate were measured to determine the filterability of the dextrans. The possible outcomes could be as follows:
(A) The dextrans having smaller diameter have greater filterability than larger dextrans.
(B) Neutral dextrans were filtered more than polycationic and polyanionic dextrans.
(C) Polycationic dextrans were filtered more than neutral and polyanionic dextrans.
(D) Polyanionic dextrans were filtered more than neutral and polycationic dextrans.
Which one of the following combinations is correct?
QUESTION ID:60
A novel enzyme was identified in humans. The following approaches are available to identify the chromosome on which the gene encoding the enzyme is present:
(A) Suppress the activity of enzyme by RNAi.
(B) Identify polymorphism in the population and carry out pedigree analysis to study its inheritance.
(C) Purify the enzyme, decipher its amino acid sequence, predict its DNA sequence and search for its presence in the available human genome sequence.
(D) Create chromosome addition lines by making somatic hybrids between human and mouse cells, identify lines showing the enzyme activity and the human chromosome present in it.
Which of the above approaches can be used?
QUESTION ID:61
In an experiment on transposition in an eukaryotic system, an intron was cloned within a transposable element and allowed to transpose from a plasmid to genomic DNA. The intron was found to be absent in the transposable element in its new location. It is
QUESTION ID:62
In a plant species, a segregating line (one that contains both homozygotes and heterozygotes at a locus) can be made homozygous by repeated selfing for several generations. What is the level of remaining heterozygosity after three generations of selting, if the level of heterozygosity in generation '0' is denoted as 1?
QUESTION ID:63
Given below, is the result of a complementation test for six independent mutants (1 to 6). '+' represents complementation; '0' represents noncomplementation Based on the above, which one of the following conclusions is correct?

QUESTION ID:64
In a hospital three babies were mixed up. The blood group of the babies were A, B and AB. In order to identify the parents of the babies, the blood groups of the parents were determined. The results obtained were:
Parent set 1 – A and AB
Parent set 2 – AB and O
Parent set 3 – B and AB
Which of the following conclusions can be definitively made?
QUESTION ID:65
There are two mutant plants. One shows taller phenotype than wild type, whereas the other has the same height as the wild type. When these two mutations were brought in together by genetic crosses, the double mutant displayed even taller phenotype than the tall mutant plants. This genetic interaction is called
QUESTION ID:66
The following table gives vascular tissue characteristics of four divisions of Tracheophyta
Identify the correct combinations:

QUESTION ID:67
Which of the following is NOT an advantage to seedbased reproduction?
QUESTION ID:68
In a study of sexual isolation in a species of salamander, scientists brought together males and females from different populations and from the same population. They observed the frequency of mating and calculated a sexual isolation index. One graph shows the
relationship between mating frequency and genetic distance, and the other shows the relationship between sexual isolation index and geographic isolation.
Choose the appropriate terms for of X1, Y1, X2 and Y2 in the figures, above.

QUESTION ID:69
As per the of International Code of Botanical Nomenclature, 2006 (Vienna Code), which of the following is a Nothospecies?
QUESTION ID:70
Which of the following groups have only two wings?
QUESTION ID:71
India has currently 17 biosphere -reserves representing different ecosystems. These conservation areas significantly differ from the conventional protected areas of the country. Identify the correct combination of attributes (A to G) that best .explains the concept of
biosphere reserve.
(A) Conservation,
(B) Education,
(C) Human habitation allowed,
(D) Human habitation not allowed,
(E) Strong legal back-up,
(F) No supporting act,
(G) Research.
QUESTION ID:72
Followings are the niche characteristics of the constituent species and resource partitioning pattern in different ecosystems. Which of these would lead to competitive exclusion of species?

QUESTION ID:73
Environmental conditions can influence accumulation of species in successional communities. Curves representing changes in forest species over time are given in the figure below. Which of the following keys is correct for the curves?

QUESTION ID:74
A plant with blue-coloured flowers was observed to attract a large number of pollinators. However, these flowers were not producing any nectar. Which of the following can be a logical explanation to the observation?
QUESTION ID:75
Three islands have identical habitat characteristics. On first island rodent species A is present at a density 325/km2. Second island has only species B at a density of 179/km2. On the third island, both A and B co-exist with densities 297/km2 and 150/km2, respectively. Which of the following can be inferred from this?
QUESTION ID:76
A few males and females of a species were introduced to a new island. Their population was monitored over several .generations and followed a pattern shown in the figure. Which of the characteristics of the species does NOT explain the pattern?

QUESTION ID:77
Plasmids are self-replicating small circular DNA elements in bacterial cells that can be said to have a stable symbiotic existence with the host cell. They often carry genes useful to the host. Which of the following is a potential threat to the evolution and stability of the symbiotic coexistence?
QUESTION ID:78
Complex eukaryotic cells may have evolved from simpler prokaryotic cells because complexity of organization increases the
QUESTION ID:79
Knox gene code transcriptionl factor important for regulation of indeterminate growth in plant shoots. These genes also regulate patterns of development of plant organs such as leaves and flowers. The figure represents a phylogenetic tree of the multigene family in some land plants. The circles represents the genes that act to maintain shoot apical meristem (equivalent to stem cells). Orthologues are genes that duplicate due to speciation and paralogues are genes that duplicate within a species.
From the figure; the following inferences were made.
(A) Multiple gene duplication occurred in vascular plants.
(B) Gene duplications may have enabled shoot diversification in vascular plants.
(C) Shoot apical meristems are regulated by orthologous genes in vascular plants.
(D) Shoot apical meristems are regulated by paralogous genes in vascular plants.
Which of the following represents a combination of correct inferences?

QUESTION ID:80
In an experiment that has continued for more than 50 years, corn has been propagated by breeding only from plants with the height amount of oil in the seeds. The average oil content is now much greater than any of the plants in the original population. The following hypotheses were proposed as explanations for this observation.
(A) Mutations occurred that increased the oil content in seeds.
(B) Plants with high oil content were stimulated to produce offspring with more oil in their seeds.
(C) The breeding led to increased frequency of alleles at multiple loci, so that new combinations of genes for even higher oil content were formed.
Which of the following represents a combination of correct statements?
QUESTION ID:81
The Galapagos finches were an important clue to Darwin's thinking about the origin of species. These finches are believed to have descended from a single ancestral species that colonized the Galapagos archipelago, America, over a short period of time. The Galapagos finches differ in their beak shape and size. Different species feed on seeds that vary in size and hardness. Which of the following is the most likely explanation for these patterns?
QUESTION ID:82
In order to demonstrate that the long tails of males attracted females in a bird species, experimenters captured and cut the tails of 'n' number of males and monitored the number of females mated by each male. They had two types of controls in the experiment.
(i) 'n' males that were not captured
(ii)'n' males that were captured, had their tails cut and then stitched back to attain the original size. The males with cut tails mated with a significantly smaller number of females than both the controls. Which of the following alternative explanations is NOT ruled out by the, experiment?
QUESTION ID:83
In the phylogenetic tree above, branch-lengths are drawn proportional to the number of changes along a lineage.
The following inferences were made from this tree.
A. Bacteria are more closely related to Eukarya than to Archaea.
B. Bacteria and Archaea are more similar to each other than either is to Eukarya.
C. Archaea and Eukarya diverged from each other after their common ancestor diverged from bacteria.
D. cells from two different plants can be mixed together and forced to fuse.
Which of the following represents a combination of correct inferences?

QUESTION ID:84
While attempting to create a disease model of poliomyelitis in mice, it was found that mice can not be infected with the said virus. Since human beings are susceptible to this viral infection, which kind of transgenic mice should be generated to have a transgenic mouse model that can be infected with polio virus? Select the right approach from below:
QUESTION ID:85
Protoplast fusion is used in plant tissue culture for various applications. In protoplast fusion:
(A) naked plant cells are used.
(B) transfer of organelles is not possible.
(C) partial genome transfer is involved.
(D) cells from two different plants can be mixed together and forced to fuse.
Which one of the following combinations of the above statements is correct?
QUESTION ID:86
Which of the following is a mismatch between the plant drug and its source?
QUESTION ID:87
Which of the following curves correctly represents the process of ethanol production by yeast?

QUESTION ID:88
Inbreeding for 5 generations led to production of homozygous transgenic mice. However, these homozygous males or females were infertile. Which of the following approach is most preferable and economical to obtain heterozygous transgenic animals continuously?
QUESTION ID:89
Following are few statements for regeneration of plants from explants/tissues.
(A) Cytokinin is required for shoot development.
(B) Auxin is required for shoot development.
(C) Auxin to cytokinin ratio is very important.
(D) Jasmonic acid is required for both root and shoot development.
Which of the following combinations of above statements is true?
QUESTION ID:90
A set of neonatal mice are divided into four groups. Group I neonates were not primed with any antigen. Group 2 neonates were primed with KLH. Group 3 neonates were primed with KLH but thymectomized. Group 4 neonates were KLH-primed, thymectomized, but reconstituted with KLH- specific CD4+ T cells. All these mice, when grown adult, were challenged with KLH and the anti-KLH IgO antibody was measured in sera. Which of the following is the collects order of magnitude of antibody response? [> = greater than, > = greater than or equal to]
QUESTION ID:91
Choose the correct sequence of events in a next generation sequencing technology-based whole genome sequencing project

QUESTION ID:92
An investigator discovers a new receptor for a known ligand and wanted to identify the binding partner of the receptor i.e. its co-receptor. The anti-receptor antibody is not available but anti GFP-antibody is available. Which one of the following strategies is most
likely to identify the co-receptor?
QUESTION ID:93
The frequency distribution of tree heights in two forest areas with different annual rainfall are given Which of the following statistical analysis will you choose to test whether rainfall has an effect on tree heights?

QUESTION ID:94
Two species of plants were sampled in 32 quadrats in a forest. The mean and variance for the occurrence of species 1 were 16.2 and 48 and species 2 were 3.6 and 3.2 respectively. Which of the following statements about the distribution of the two species in these quadrats is supported by these findings?
QUESTION ID:95
Poly-L-Iysine exists in pure α-helix, β-sheet and random coiled conformation depending upon the solvent conditions. Tile values of mean residue ellipticity at 220 nm ([θ]220) are -35,700, -13,800 and +3,900 deg cm2 dmol-1 for α-helix, β-sheet and random coil
conformations of this polypeptide, respectively. The polypeptide exists in α- helix conformation at pH 10.8 and 250 C.
Addition of urea leads to a two state transition between α-helix and random coil conformation. It has been observed that [θ]222 of the polypeptide is -14800 degcm2dmol-1in the presence of 6M urea. The percentage of the polypeptide in α-helix conformation is:
QUESTION ID:96
Given below, is the result of a complementation test for six independent mutants (1 to 6)