Previous Year Questions

QUESTION ID:1

Factor IX is essential for blood clotting. Deficiency of Factor IX could be corrected by delivering factor IX gene using viral vectors. In an experiment the gene for Factor IX was cloned appropriately into Adenovirus (AV), Adeno-associated virus (AAV) and Retrovirus (RV). Retrovirus integrate the gene into the dividing cells. AAV integrates partially into non-dividing cells. AV does not integrate the gene but transfects both dividing and non-dividing cells.

Following expression profile for Factor IX was observed when the three vectors were injected' intra-muscularly into three groups of experimental mice. Which one of the following outcomes is correct?