Previous Year Questions

QUESTION ID:2

100 g of inorganic compound X.5H20 containing a volatile impurity was kept in an oven at 150 0C for 60 minutes. The weight of residue after heating is 8 g. The percentage of impurities in X was

QUESTION ID:3

Two moles each of oxygen (O2) and hydrogen (H2) are in two separate containers, each of volume Vo and at temperature 150 0C and 1 Atmospheric pressure. The two were allowed to react in third container to form water vapors until hydrogen is exhausted. When the temperature of the mixture in the third container was restored 150 0C, its pressure become 1 atmospheric. The volume of container must be

QUESTION ID:4

The mineral talc is used in the manufacture of soap becuase A. gives bulk to product B. Kills bacteria C. Gives fragrance D. is soft and does not scratch the skin Which of the following is correct reason?  

QUESTION ID:5

On a certain night the moon in its waning phase was half moon. At midnight the moon will be

QUESTION ID:6

Growth of an organism was monitored at regular intervals of times and shown in the graph below. Around what time is the rate of growth zero?
The zero growth rate will be observed during

QUESTION ID:7

The ends of rope are fixed to two pegs such that rope remains slack. A pencil is placed against rope and moved, such that the rope always remains taut. The shape of the curve traced by pencil would be a part of

QUESTION ID:8

Four sedimentary rocks A, B, C and D are intruded by igneous rock R as shown in cross section diagram. Which of the following is correct about their ages?

QUESTION ID:9

A gemstone is irradiated in a nuclear reactor for 5 days. Ten days after irradiation, the activity of the chromium isotope in gemstone is 600 disintegration per hour. What is the activity of chromium isotope 5 days after irradiation if its half life of is 5 days?

QUESTION ID:10

Displacement versus time curve for a body is shown in the figure. Select the graph that correctly shows the variation of the velocity with time. Which of the following is correct representation of velocity with respect to time for same body?

QUESTION ID:11

The spring balance in figure A reads 0.5 kg and the pan balance in figure B reads 3.0 Kg. If iron block is suspended from spring balance is partially immersed in water in the beaker (Figure C). The spring balance now reads 0.4 kg. The reading on the pan balance in figure C is

QUESTION ID:12

The angles of a right angled triangle shaped garden are in arithmetic progression and the smallest side is 10.00 m. The he total length of the fencing of the garden in m is

QUESTION ID:13

The rabbit population in community A increases by 25 % per year while in community B increases at 50 % per year respectively. If the present populations of A and B are equal, the ratio of the number of rabbits in B to A after two years will be?

QUESTION ID:14

AB is diameter of semicircle as shown in diagram. If AQ=2AP then which of the following is correct

QUESTION ID:15

A Tall plant with Red seeds (both dominant traits) was crossed with a dwarf plant with white seeds. If the segregating progeny produced equal number of tall red and dwarf white plants, what would be the genotype of the parents?

QUESTION ID:16

During ice skating the blades of the ice skater’s shoe exerts pressure on the ice. Ice skater can efficiently skate on ice because

QUESTION ID:17

The strain in a solid subjected to continuous stress is plotted. Which of the following statement is true?

QUESTION ID:18

The area of shaded region in cm²

QUESTION ID:19

Three sunflower plants were placed in conditions as indicated below
Plant A: Still air
Plant B: moderately turbulent air
Plant C: Still air in dark
Which of the following statement is correct?

QUESTION ID:20

Which of the following is indicated by the accompanying diagram?

QUESTION ID:21

Which nitrogen of adenosine gets protonated if pH of nucleoside is lowered from 7 to 3?

QUESTION ID:22

Phosphotidyl serine, an important component of biological membrane. is located in  

QUESTION ID:23

The oligopeptide, with F-A-R-P-M-T-S-R-P-G-F is treated with trypsin, chymotrypsin and carboxypeptidase-B. Apart from original, the number of fragments obtained will be

QUESTION ID:24

The word “fermentation” is used in biochemistry and Microbial technology to denote different phenomenon. If the former is called C and latter is called T. Which of the following statement is true?  

QUESTION ID:25

All cytosolic proteins have nuclear export signals that allows them to be removed from nucleus when it reassembles after

QUESTION ID:26

ATP- binding cassette (ABC) transporters

QUESTION ID:27

Which one of the following interactions plays a major role in stabilizing B-DNA?

QUESTION ID:28

Which of the following statement is NOT true about small interfering RNA (siRNA)?  

QUESTION ID:29

Regulatory elements for expression of ribosomal RNA genes resides in the

QUESTION ID:30

Presence of an internal ribosomal entry site (IRES) in mRNA

QUESTION ID:31

Mycobacterium tuberculosis is an intra-cellular bacterium. It prefers to infect

QUESTION ID:32

Integrin molecule link extracellular matrix (ECM) to the actin cytoskeleton of cell. Integrin binds to which of the following ECM macromolecules?

QUESTION ID:33

Major stimulus for spore formation in bacteria is

QUESTION ID:34

Which of the following matches of oncogene-protein product is NOT correct?

QUESTION ID:35

Which of the following statement is INCORRECT in relation to treatment of pre-B cell with phorbol ester?

QUESTION ID:36

CD19 is a marker for 

QUESTION ID:37

Given below are fate map of two organisms and the pattern by which embryos undergo cleavage. Which of the following is/are the right combination(s)?  

QUESTION ID:38

Ced-9 gene appears to be a binary switch that regulates cell survival and apopotosis in nematodes. Considering that CED-9 protein can bind to and inactivate CED-4, which of the following would lead to apoptosis?

QUESTION ID:39

In case of is Xenopus levis which cells make up the Knewkoop center and Spemann’s organizer? 

QUESTION ID:40

Photosystem II functions as a light dependent water plastoquinone oxidoreductase. What are the names of two reaction center protein that bind electron transfer prosthetic group, such as P680, pheophytin and plastoquinone? 

QUESTION ID:41

Which one of the following combinations of secondary metabolite biosynthetic pathway result in the biosynthesis of terpenes? 

QUESTION ID:42

Symbiotic biological nitrogen fixation takes place with the association between a plant and a nitrogen fixing prokaryote as shown in the following table:

The correct combination is: 

QUESTION ID:43

Plants have evolved with multiple photoreceptors, which can perceive specific wavelength of light. Which of the following statement is correct about photoreceptors?

QUESTION ID:44

Which of the following statement describes the process of phloem loading?

QUESTION ID:45

Which of the following is responsible for initiation of maternal behaviour in first time pregnant rats after parturition?

QUESTION ID:46

Which one of the following changes will occur in the cell membrane of nodal tissue of heart, which results in an increased heart rate due to stimulation of sympathetic nerves?

QUESTION ID:47

A person takes 1.0 ml of insulin injection daily at 8:00 AM. His son gave 1.5 ml of insulin at 8:00 AM considering the father will go to party and eat more during lunch. The father also avoided breakfast, as he planned to eat more during lunch. Which one of the following events will occur?

QUESTION ID:48

A gene encoding t-RNA undergoes a mutational event in its anticodon region that enables it to recognize a mutant nonsense codon and permit completion of translation. Such a mutation is known as

QUESTION ID:49

Mutation at two different loci of the same gene X results in altered functions. These two mutated versions of gene X are called

QUESTION ID:50

Spermatogonial stem cell undergoes extensive metamorphosis to become a spermatozoan. Meiosis leads to the formation of spermatid containing 22 autosomes and one sex chromosome. A male mouse was found in a colony which always produced only female puff upon matting. Which one pf following is a possible reason

QUESTION ID:51

Two pure line of corn have mean cob length of 9 cm and 3 cm, respectively. The polygenes involved in this trait exhibit additive gene action. Crossing these two lines is expected to produce a progeny population with mean cob length of

QUESTION ID:52

How many genetically different gametes can be made by an individual of genotype AaBbccDDEe?

QUESTION ID:53

A paraphyletic group

QUESTION ID:54

Which of the following organism is widely used as a biocontrol in organic farming?

QUESTION ID:55

Which of the following is NOT an adaptive modification in a xerophytic plant?

QUESTION ID:56

If the milk is left open, lactose is fermented first to produce acid. This is followed by protelytic bacteria which increases the pH. Ultimately milk fats are degraded to produce rancidity. This is an example of

QUESTION ID:57

Based on per molecule, which of the following gas has the most powerful greenhouse effect?

QUESTION ID:58

The Hardy-Wienberg principle comes from considering what happens when Medelian genes act on population. The model predicts that there will be no change in allele frequencies when

QUESTION ID:59

Among the following events in history of life
a. prokaryotic cell
b. eukaryotic cell
c. natural selection
d. organic molecules
e. self replicating molecule

Which is the correct chronological order?

QUESTION ID:60

Sexual selection results in variation in the reproductive success of males, often due to female choice with particular phenotypes. This type of sexual selection is because

QUESTION ID:61

Which is best method for checking mycoplasma contamination in a mammalian cell line?

QUESTION ID:62

Major disadvantage of using liposome as targeted drug delivery vehicle is that

QUESTION ID:63

 If ‘r’ denotes correlation coefficient and ‘m’ denotes slope of regression line, interchanging X and Y axes would

QUESTION ID:64

Which of the following statement is NOT true during infection of plant cell by Agrobacterium?

QUESTION ID:65

Which of the following does not represents strategy for phytoremediation?

QUESTION ID:66

Among existing technologies, which of the following vector system would you prefer to use for generating a library for 140 kb eukaryotic genomic DNA fragments, while giving due consideration to size as well as stability of insert?

QUESTION ID:67

The use of biotinylated secondary antibody in ELISA?

QUESTION ID:68

Secondary sewage treatment involves

QUESTION ID:69

Site specific recombination results in precise DNA rearrangements, which is limited to specific sequences. The enzymes that are important to carry out the process are

QUESTION ID:70

To replace animal use in testing hepatic toxicity of a drug on trial, which one of the following would be used in vitro to be closest to the in vivo scenario?

QUESTION ID:71

A plot of V/[S] versus V is generated for an enzyme catalyzed reaction, and a straight line is obtained. Indicate the information that can be obtained from the plot.

QUESTION ID:72

Phosphorylation of ADP to ATP occurs through energy metabolism, comprising oxidative phosphorylation or substrate level phosphorylation or photo-phosphorylation (in plants). ATP can also be formed from ADP through the action of adenylate kinase. Crystal structure determination of adenylate kinase shows that the C-terminal region has the sequence -val-asp-asp-val-phe-ser-gln-val-cys-thr-his-leu-aspthr- leu-lys.
What can be a possible conformation of the sequence?

QUESTION ID:73

Consider a 51-residue long protein containing only 100 bonds about which rotation can occur. Assume that 3 orientations per bond are possible. Based on these assumptions, how many conformations will be possible for this protein?

QUESTION ID:74

Phosphoglucomutase is added to 0.1 M glucose-1- phosphate (G-6-P). The standard free energy change of the reaction, G-6-P⇄G-1-P is 1.8 kcal/mole at 25°C. The equilibrium concentrations of G-6-P and G-1-P, respectively are

QUESTION ID:75

Differential scanning calorimetric study of calf thymus DNA was carried out to measure midpoint of thermal denaturation (Tm). ΔHm (enthalpy change at Tm) and ΔCp (constant-pressure heat capacity change). It has been observed that ΔCp =0, Tm =75.5°C and ΔHm=50.4 kcal/mole. The Gibbs free energy change at 37°C is

QUESTION ID:76

The following reactions are part of the citric acid cycle. The numbers in parenthesis indicate the number of carbon atoms in each molecule.

Isocitrate(6) ketoglutarate(5) succinyl

CoA(4) succinate(4) fumarate(4)

Which of the following sequences of the reaction systems A→D is correct?

QUESTION ID:77

The respiratory chain is relatively inaccessible to experimental manipulation in intact mitochondria. Upon disrupting mitochondria with ultrasound, however, it is possible to isolate functional sub mitochondrial particles, which consist of broken cristae that have resealed inside out into small closed vesicles. In these vesicles the components that originally faced the matrix are now exposed to the surrounding medium. This arrangement helps in studying electron transport and ATP synthesis because:

QUESTION ID:78

Cystic fibrosis(CF) trans membrane conductance regulator (CFTR) protein is known to be a cAMP- dependent Clchannel. CF patients (with mutant CFTR proteins) show reduced Cl- permeability and as a result exhibit elevated Cllevel in sweat. To prove this, CFTR proteins (both wild type and mutant) are inserted in a model membrane (liposome) and Cltransport is followed with radioactive Cl-.it is known that topology of CFTR in membrane is important for its function. Despite no proteolytic degradation of denaturation of CFTR proteins,wild type CFTR failed to transport Cl- in liposome.
Which of the following is the correct explanation of this?

QUESTION ID:79

Which of the following statement regarding aquaporin or water channels is NOT correct?

QUESTION ID:80

The intestinal absorption of glucose is impaired by use of ovabain, an inhibitor of Na+-K+ ATPase. Indicate the correct explanation

QUESTION ID:81

A synthetically prepared mRNA contains repetitive AU sequences. The mRNA was incubated with mammalian cell extract which contains ribosomes, tRNA s and all the factors required for protein synthesis. Assuming no initiation codon is required for protein synthesis, which of the following peptides will most likely be synthesized?

QUESTION ID:82

Hoechst 33342 is a membrane-permanent dye that fluoresces when it binds to DNA through intercalating process. If a population of cells is incubated briefly with Hoechst dye and stored in flow cyclometer the cells display various levels of fluorescence in different phases of cell cycles as shown in figure below ( marked as X,Y,Z)
Which of the following is correct?
 

QUESTION ID:83

During cell cycle regulation in eukaryotes, there are posttranslational modifications of protein factors, which act as switches for different phases of cell cycle. A cell population of yeast was transfected with gene for wee 1 kinase (modifies cdc2 protein).Assuming that the transfection efficiency was 50% only, which of the following graphical representation of the results is most appropriate?