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Previous Year Questions

TLS Online TPP Program

QUESTION ID:1

Read the following passage and answer the next five questions by choosing the correct options:
Multicultural emphasises the importance of cultural diversity. It recognises the dignity and importance of cultural distinctiveness. It reiterates that cultural differences are natural phenomena. Cultural diversity. diverse ideas, perspectives and beliefs enhance our vision of a better society. Multiculturalism stands for heterogeneity and diversity. It is an inclusive process in which all cultures are valued.
In India, immigration and multiculturalism are as old as recorded history. Since time immemorial, wave after wave of ethnically and culturally diverse people have poured into India, settled here, and assimilated into its mosaic. Each community, while interacting and being influenced by the others, retained its own identity. customs, beliefs and ways of life. It has truly been said that Indian culture is a 'culture of cultures', like a beehive of interlocking cells.
Hinduism has played a seminal role in shaping the Indian mind and character. It has dogma, no prophet, no single sacred book. It believes in freedom of thought and expression. It encompasses different forms of belief: monotheism, polytheism, agnosticism as well as atheism. Hinduism is also the foundation of a general sprit of tolerance and acceptance of the 'other', the belief that different paths can lead to the same goal. Hinduism's flexibility has endowed Indian civilisation with a unique resilience and power of absorptive survival.
The 700 years of Muslim rule from the 11-12th century bequeathed a mixed legacy. Politically, Islam in India represented subjugation. But culturally, it generated outstanding creative achievement and synthesis. The centuries of Muslim rule impacted all aspects of Indian life producing a composite Indi-Islamic culture.
British colonial rule replaced Muslim rule, adding one more layer to India's plural personality. India's
exposure to the West was both debilitating and nourishing. On the one hand, colonial rule devalued Indian
civilisation by claiming and justifying 'civilising mission' of British. On the other hand, the work of great European Ideologists helped India rediscover her classical literature, her forgotten wisdom and values.
It is striking how the intellectual journey of the leaders of the Indian renaissance went from India to the the West, before returning to India with a new-found sense of Indianness. All of them represented a mingling of East and West, a synthesis of European and Indian thought.
This was the background to the emergence of an independent, democratic India in 1947, after the bloodbath of Partition. We are the most complex and diverse society on earth. Today's India has over a billion Hindus, 150 million Muslims. 24 million Christians and 24 million Sikhs, apart from several smaller but important denominations. In addition to English and Hindi, we speak more than 20 major languages and some 22,000 dialects. Each religion is further sliced and diced by caste, sub-caste and region. There are also thousands of
tribal groups with distinct ethnic and cultural identities. Each of India's states has its own centuries-old flourishing culture, with further internal diversions.

Match List I with List II to explain the terms in List II
Choose the correct answer from the options given below:

QUESTION ID:2

Read the following passage and answer the next five questions by choosing the correct options:
Multicultural emphasises the importance of cultural diversity. It recognises the dignity and importance of cultural distinctiveness. It reiterates that cultural differences are natural phenomena. Cultural diversity. diverse ideas, perspectives and beliefs enhance our vision of a better society. Multiculturalism stands for heterogeneity and diversity. It is an inclusive process in which all cultures are valued.
In India, immigration and multiculturalism are as old as recorded history. Since time immemorial, wave after wave of ethnically and culturally diverse people have poured into India, settled here, and assimilated into its mosaic. Each community, while interacting and being influenced by the others, retained its own identity. customs, beliefs and ways of life. It has truly been said that Indian culture is a 'culture of cultures', like a beehive of interlocking cells.
Hinduism has played a seminal role in shaping the Indian mind and character. It has dogma, no prophet, no single sacred book. It believes in freedom of thought and expression. It encompasses different forms of belief: monotheism, polytheism, agnosticism as well as atheism. Hinduism is also the foundation of a general sprit of tolerance and acceptance of the 'other', the belief that different paths can lead to the same goal. Hinduism's flexibility has endowed Indian civilisation with a unique resilience and power of absorptive survival.
The 700 years of Muslim rule from the 11-12th century bequeathed a mixed legacy. Politically, Islam in India represented subjugation. But culturally, it generated outstanding creative achievement and synthesis. The centuries of Muslim rule impacted all aspects of Indian life producing a composite Indi-Islamic culture.
British colonial rule replaced Muslim rule, adding one more layer to India's plural personality. India's
exposure to the West was both debilitating and nourishing. On the one hand, colonial rule devalued Indian
civilisation by claiming and justifying 'civilising mission' of British. On the other hand, the work of great European Ideologists helped India rediscover her classical literature, her forgotten wisdom and values.
It is striking how the intellectual journey of the leaders of the Indian renaissance went from India to the the West, before returning to India with a new-found sense of Indianness. All of them represented a mingling of East and West, a synthesis of European and Indian thought.
This was the background to the emergence of an independent, democratic India in 1947, after the bloodbath of Partition. We are the most complex and diverse society on earth. Today's India has over a billion Hindus, 150 million Muslims. 24 million Christians and 24 million Sikhs, apart from several smaller but important denominations. In addition to English and Hindi, we speak more than 20 major languages and some 22,000 dialects. Each religion is further sliced and diced by caste, sub-caste and region. There are also thousands of
tribal groups with distinct ethnic and cultural identities. Each of India's states has its own centuries-old flourishing culture, with further internal diversions.


Which of the following is not a feature of multiculturalism?

QUESTION ID:3

Read the following passage and answer the next five questions by choosing the correct options:
Multicultural emphasises the importance of cultural diversity. It recognises the dignity and importance of cultural distinctiveness. It reiterates that cultural differences are natural phenomena. Cultural diversity. diverse ideas, perspectives and beliefs enhance our vision of a better society. Multiculturalism stands for heterogeneity and diversity. It is an inclusive process in which all cultures are valued.
In India, immigration and multiculturalism are as old as recorded history. Since time immemorial, wave after wave of ethnically and culturally diverse people have poured into India, settled here, and assimilated into its mosaic. Each community, while interacting and being influenced by the others, retained its own identity. customs, beliefs and ways of life. It has truly been said that Indian culture is a 'culture of cultures', like a beehive of interlocking cells.
Hinduism has played a seminal role in shaping the Indian mind and character. It has dogma, no prophet, no single sacred book. It believes in freedom of thought and expression. It encompasses different forms of belief: monotheism, polytheism, agnosticism as well as atheism. Hinduism is also the foundation of a general sprit of tolerance and acceptance of the 'other', the belief that different paths can lead to the same goal. Hinduism's flexibility has endowed Indian civilisation with a unique resilience and power of absorptive survival.
The 700 years of Muslim rule from the 11-12th century bequeathed a mixed legacy. Politically, Islam in India represented subjugation. But culturally, it generated outstanding creative achievement and synthesis. The centuries of Muslim rule impacted all aspects of Indian life producing a composite Indi-Islamic culture.
British colonial rule replaced Muslim rule, adding one more layer to India's plural personality. India's
exposure to the West was both debilitating and nourishing. On the one hand, colonial rule devalued Indian
civilisation by claiming and justifying 'civilising mission' of British. On the other hand, the work of great European Ideologists helped India rediscover her classical literature, her forgotten wisdom and values.
It is striking how the intellectual journey of the leaders of the Indian renaissance went from India to the the West, before returning to India with a new-found sense of Indianness. All of them represented a mingling of East and West, a synthesis of European and Indian thought.
This was the background to the emergence of an independent, democratic India in 1947, after the bloodbath of Partition. We are the most complex and diverse society on earth. Today's India has over a billion Hindus, 150 million Muslims. 24 million Christians and 24 million Sikhs, apart from several smaller but important denominations. In addition to English and Hindi, we speak more than 20 major languages and some 22,000 dialects. Each religion is further sliced and diced by caste, sub-caste and region. There are also thousands of
tribal groups with distinct ethnic and cultural identities. Each of India's states has its own centuries-old flourishing culture, with further internal diversions.

The writer says that Indian "culture is a culture of cultures like a beehive of interlocking cells." By this he means.

QUESTION ID:4

Read the following passage and answer the next five questions by choosing the correct options:
Multicultural emphasises the importance of cultural diversity. It recognises the dignity and importance of cultural distinctiveness. It reiterates that cultural differences are natural phenomena. Cultural diversity. diverse ideas, perspectives and beliefs enhance our vision of a better society. Multiculturalism stands for heterogeneity and diversity. It is an inclusive process in which all cultures are valued.
In India, immigration and multiculturalism are as old as recorded history. Since time immemorial, wave after wave of ethnically and culturally diverse people have poured into India, settled here, and assimilated into its mosaic. Each community, while interacting and being influenced by the others, retained its own identity. customs, beliefs and ways of life. It has truly been said that Indian culture is a 'culture of cultures', like a beehive of interlocking cells.
Hinduism has played a seminal role in shaping the Indian mind and character. It has dogma, no prophet, no single sacred book. It believes in freedom of thought and expression. It encompasses different forms of belief: monotheism, polytheism, agnosticism as well as atheism. Hinduism is also the foundation of a general sprit of tolerance and acceptance of the 'other', the belief that different paths can lead to the same goal. Hinduism's flexibility has endowed Indian civilisation with a unique resilience and power of absorptive survival.
The 700 years of Muslim rule from the 11-12th century bequeathed a mixed legacy. Politically, Islam in India represented subjugation. But culturally, it generated outstanding creative achievement and synthesis. The centuries of Muslim rule impacted all aspects of Indian life producing a composite Indi-Islamic culture.
British colonial rule replaced Muslim rule, adding one more layer to India's plural personality. India's
exposure to the West was both debilitating and nourishing. On the one hand, colonial rule devalued Indian
civilisation by claiming and justifying 'civilising mission' of British. On the other hand, the work of great European Ideologists helped India rediscover her classical literature, her forgotten wisdom and values.
It is striking how the intellectual journey of the leaders of the Indian renaissance went from India to the the West, before returning to India with a new-found sense of Indianness. All of them represented a mingling of East and West, a synthesis of European and Indian thought.
This was the background to the emergence of an independent, democratic India in 1947, after the bloodbath of Partition. We are the most complex and diverse society on earth. Today's India has over a billion Hindus, 150 million Muslims. 24 million Christians and 24 million Sikhs, apart from several smaller but important denominations. In addition to English and Hindi, we speak more than 20 major languages and some 22,000 dialects. Each religion is further sliced and diced by caste, sub-caste and region. There are also thousands of
tribal groups with distinct ethnic and cultural identities. Each of India's states has its own centuries-old flourishing culture, with further internal diversions.


The colonial rule in India, while justifying its "Civilising mission" also helped India rediscover her literature, wisdom and values. The statement affirms that:

QUESTION ID:5

Read the following passage and answer the next five questions by choosing the correct options:
Multicultural emphasises the importance of cultural diversity. It recognises the dignity and importance of cultural distinctiveness. It reiterates that cultural differences are natural phenomena. Cultural diversity. diverse ideas, perspectives and beliefs enhance our vision of a better society. Multiculturalism stands for heterogeneity and diversity. It is an inclusive process in which all cultures are valued.
In India, immigration and multiculturalism are as old as recorded history. Since time immemorial, wave after wave of ethnically and culturally diverse people have poured into India, settled here, and assimilated into its mosaic. Each community, while interacting and being influenced by the others, retained its own identity. customs, beliefs and ways of life. It has truly been said that Indian culture is a 'culture of cultures', like a beehive of interlocking cells.
Hinduism has played a seminal role in shaping the Indian mind and character. It has dogma, no prophet, no single sacred book. It believes in freedom of thought and expression. It encompasses different forms of belief: monotheism, polytheism, agnosticism as well as atheism. Hinduism is also the foundation of a general sprit of tolerance and acceptance of the 'other', the belief that different paths can lead to the same goal. Hinduism's flexibility has endowed Indian civilisation with a unique resilience and power of absorptive survival.
The 700 years of Muslim rule from the 11-12th century bequeathed a mixed legacy. Politically, Islam in India represented subjugation. But culturally, it generated outstanding creative achievement and synthesis. The centuries of Muslim rule impacted all aspects of Indian life producing a composite Indi-Islamic culture.
British colonial rule replaced Muslim rule, adding one more layer to India's plural personality. India's
exposure to the West was both debilitating and nourishing. On the one hand, colonial rule devalued Indian
civilisation by claiming and justifying 'civilising mission' of British. On the other hand, the work of great European Ideologists helped India rediscover her classical literature, her forgotten wisdom and values.
It is striking how the intellectual journey of the leaders of the Indian renaissance went from India to the the West, before returning to India with a new-found sense of Indianness. All of them represented a mingling of East and West, a synthesis of European and Indian thought.
This was the background to the emergence of an independent, democratic India in 1947, after the bloodbath of Partition. We are the most complex and diverse society on earth. Today's India has over a billion Hindus, 150 million Muslims. 24 million Christians and 24 million Sikhs, apart from several smaller but important denominations. In addition to English and Hindi, we speak more than 20 major languages and some 22,000 dialects. Each religion is further sliced and diced by caste, sub-caste and region. There are also thousands of

tribal groups with distinct ethnic and cultural identities. Each of India's states has its own centuries-old flourishing culture, with further internal diversions.


Match List I with List II

Choose the correct answer from the options given below:

QUESTION ID:6

Choose the correct option which improves the sentence grammatically.

He saw looking through the window, the beggar standing right there.

QUESTION ID:7

Prachi knows all the most recent facts about politics. The suitable phrasal verbs for underlined part is:

QUESTION ID:8

Match List I with List II Match the classes used in list I with their type in list II.
Choose the correct answer from the options given below:

QUESTION ID:9

Out of the following options choose the correct sentence:

QUESTION ID:10

Choose the correctly spelt word the given options:-

QUESTION ID:11


QUESTION ID:12

A man covers a distance of 12km by walking at a speed of 4km/h. How much distance (in km) would he cover in the same time, if he walks at a speed of 6 km/h?

QUESTION ID:13

A sum becomes 5 times of itself at 10% per annum simple interest. At what rate of simple interest will it becomes 10 times during the same period?

QUESTION ID:14

If the side of a cube is increased by 25% then volume of the cube will increase by (correct to one decimal place):

QUESTION ID:15

A man buys two watches for Rs1750. He sells the first one at a loss of 10% while on the second he earns a profit of 15%. If one the whole he gets no profit no loss then what is the cost of cheaper watch?

QUESTION ID:16

In a certain code language, HEAT is written as SVZG, then what will be the code of WILD?

QUESTION ID:17

S. the son-in-low of Q. is the brother-in-low of P who is the brother of R. How is P related to Q?

QUESTION ID:18

Which of these conclusion definitely follows from the given statement.
Statement: In a test cricket match, the total runs made by a team were 500. Out of those 380 runs made by spinners.

Conclusion:
I. 60% of the team consists of spinners.
II. The opening batsmen were spinners.

QUESTION ID:19

Choose the number which is different from others in the group.
523,734,981,853,648

QUESTION ID:20

Two positions of a dice are shown below. When number 1 is on the top, what number will be at the bottom?


QUESTION ID:21

Through which of these straits the International Date Line passes?

QUESTION ID:22

Match List I with List II

Choose the correct answer from the options given below:

QUESTION ID:23

Who among the following has been honored with Major Dhyan Chand Khel Ratna Award 2022?

QUESTION ID:24

Given below are two statements:

Statement I: The fuse wire in an electric circuit saves the circuit from getting overheated.
Statement II: A fuse is a wire whose resistance is low and melting point is high.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:25

Choose the correct statements.

A. The president is the ex-officio chairman of National development council (NDC)
B. The NDC was formed in 1952.
C. The NDC was formed to associate the states in the formulations of the plan.
D. Function of NDC was also to review security of borders of India.

Choose the correct answer from the options given below:

QUESTION ID:26

The largest membranous cellular organelle is :

QUESTION ID:27

Which of the following cellular organelle is called as digestive tract of the cell?

QUESTION ID:28

Mitochondria is involved in -

QUESTION ID:29

Size exclusion chromatography or gel filtration chromatography separates proteins based on:

QUESTION ID:30

In spectrophotometric measurement of proteins, which of the following amino acids contribute the maximum?

QUESTION ID:31

One of the following is not related to enzyme linked immunosorbent assay (ELISA)

QUESTION ID:32

If molecular weight of a protein is 2,20,000 gm per mole, what would be the number of amino acids in the protein, assuming mean molecular weight of an amino acid to be 110 gm per mole?

QUESTION ID:33

Which of the following statement is incorrect?

QUESTION ID:34

Find the wrong one out -

QUESTION ID:35

A phosphodiester bond forms:

QUESTION ID:36

Watson and Crick base pairing is ?

QUESTION ID:37

The complementary sequence for the DNA stretch 'GATCAATCGAACT', would be

QUESTION ID:38

The two common antioxidants that also act as pro-oxidants in biological systems are

QUESTION ID:39

Diabetes is a:

QUESTION ID:40

An oxyhemoglobin molecule contains ?

QUESTION ID:41

Which of the following mutations is least deleterious in a genome:

QUESTION ID:42

Given below is the triple nature of codon, the possible permutation of four bases (A, G, T. C) is:

QUESTION ID:43

DNA photolyases are the enzymes that convert:

QUESTION ID:44

What are the possible number of reading frames in any given double stranded DNA sequence :

QUESTION ID:45

During translation, the directionality of polypeptide synthesis is ?

QUESTION ID:46

Find the odd one among the following:

QUESTION ID:47

The catalytic efficiency of an enzyme refers to

QUESTION ID:48

Km of an enzyme - catalysed reaction is :

QUESTION ID:49

Identify the wrong statement about Penicillin.

QUESTION ID:50

The most abundant enzyme on Earth is

QUESTION ID:51

Gmelin's test and Van den Bergh reaction are used for:

QUESTION ID:52

Which of the following are involved in buffering our blood system ?

QUESTION ID:53

The amino acid in renal tubular cells that forms ammonia, which is finally excreted as NH4 is:

QUESTION ID:54

Rifampicin inhibits :

QUESTION ID:55

The acid - fastness of mycobacteria is due to :

QUESTION ID:56

The branch of biology that involves creation of small living organisms like mycoplasma etc. is called as:

QUESTION ID:57

Which group of the antibiotics inhibit translation by binding to the 50s ribosomal subunit?

QUESTION ID:58

Given that ∆G = ∆H = T∆S, with reference to it, identify the wrong statement:

QUESTION ID:59

The
Reaction 1:
Glucose + Pi â†’ Glucose-6-Phosphate + H2O
can only occur when the
Reaction 2:
ATP â†’ ADP + Pi
occurs. This is because :

QUESTION ID:60

Oxidation of one molecule of FADH2 in the respiratory chain, forms how many molecules of ATP?

QUESTION ID:61

The breakdown of the long chain fatty acids to acetyl CoA via ẞ-oxidation takes place in :

QUESTION ID:62

During glycolysis, conversion of 1 mole of fructose 1. 6-bisphosphate to 2 moles of pyruvate, leads to the formation of:

QUESTION ID:63

The concentration of OH- in a solution with H+ concentration of 1.3 X 10 -4 M is :

QUESTION ID:64

IgM is a pentamer. Upon visualisation of a pure IgM by electrophoresis on a reducing polyacrylamide gel, the number of protein bands to be visible on the gel would be :

QUESTION ID:65

A plot between the Î¦ and Î¨ dihedral angles of a peptide bond is called as:

QUESTION ID:66

Give below are two statements: one is labelled as Assertion A and the other is labelled as Reason R

Assertion A: Protein folding is essential for structure and function is still an unresolved problem in biology. Protein folding problems lead to aggregation and is a cause for many diseases:
Reason R: Levinthal's paradox is a theoretical calculation of the time needed for a protein to fold. Accordingly, a polypeptide may take billions of years to fold if all the possible conformations are exercised during protein folding.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:67

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: Prokaryotes have three RNA polymerases. Prokaryotic RNA pol II synthesizes ribosomal RNAs.
Reasons R: In Eukaryotes RNA Polymerase II synthesizes mRNA and is sensitive to low concentration of Î±- amanitin.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:68

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R

Assertion A: Klinefelter's syndrome have minor phenotypic anomalies with small testis and enlarged breasts. These individuals have 47 chromosomes with 44 autosomes plus XXY.
Reason R: Males with XYY syndrome have two Y chromosomes. Such individuals have anti social behavior and aggression. Their frequency is approximately 1 to 650.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:69

Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R.

Assertions A: Protein kinases catalyze the transfer of gamma (y) - phosphoryl group of ATP to proteins. Serine, threonine or tyrosine are the general amino acids that are phosphorylated.
Reason R: Phosphorylation of proteins by protein kinases makes them aggregated and non-functional with subsequent degradation.

In the light of the above statements, choose the most appropriate answer from the options given below :

QUESTION ID:70

Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:

Assertion A: While the pKa of a free lysine is 10.5, the pKa of lysine decreases to 6.6 when present in the active site of Acetoacetate decarboxylase.
Reason R: The decreased pK, of lysine in the active site is due to the electrostatic effect of nearby positive charges.

In the light of the above statements, choose the most appropriate answer from the options given below :

QUESTION ID:71

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:

Assertion A: Sum of all the proteins functioning in a given cell is called the proteome: Proteomics is the systematic characterization of this proteome under a given condition.
Reason R: Expression of genome under a particular condition and its translation is the basis of cell's proteome.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:72

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:

Assertion A: Treatment of monosaccharides with sodium amalgam reduces their aldehyde and keto groups to corresponding acid:
Reason R: D-Dulcitol and D-Sorbitol are the corresponding alcohols of D-galactose and D-glucose, respectively.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:73

Malate, Fumarate and succinate precede the formation of oxaloacetate in the citric acid cycle. Find the option which shows correct order of their formation in the citric acid cycle.

A. Malate
B. Fumarate
C. Oxaloacetate
D. Succinate

Choose the correct answer from the options given below:

QUESTION ID:74

Phosphoryl transfer reactions are essential for the energy content of a cell. Find the correct answer in which the following phosphorylated molecules have been arranged in a decreasing order of their phosphoryl transfer potentials:

A. Adenosine triphosphate
B. 1. 3-bisphosphate glycerate
C. Phosphoenol pyruvate
D. Glucose-6-phosphate
E. Glucose-3- phosphate

Choose the correct answer from the options given below:

QUESTION ID:75

In analogy with central dogma of biology, how will you arrange the following omics in a correct sequence:

A. Metabolomics
B. Proteomics
C. Genomics
D. Transcriptomics
E. Phenotype or phenomics

Choose the correct answer from the options given below:

QUESTION ID:76

Nucleotides, Nucleosides, purines and pyrimidines are the building blocks of DNA and RNA. Based on their molecular weight, arrange these molecules in an ascending order.

A. Purine
B. Nucleotide
C. Pyrimidine
D. Nucleoside
E. Phosphate

Choose the correct answer from the options given below:

QUESTION ID:77

Reverse transcriptase is used for synthesizing cDNA from RNA. Which of the following option represents the correct order of the given steps?

A. Annealing of the oligo dT primer to mRNA
B. DNA polymerase I and dNTPs form ds DNA
C. Reverse transcriptase forms the complementary single stranded DNA
D. mRNA is degraded with alkali
E. Downstream analysis of dsDNA

Choose the correct answer from the options given below:

QUESTION ID:78

DNA cloning is an essential tool in recombinant DNA technology. Arrange the different steps of DNA cloning in proper sequential order.

A. Restriction digestion of the insert and plasmid.
B. Selection of the host cells or transformants having the recombinant DNA
C. in vitro DNA ligation
D. Transformation of the ligated DNA.
E. Confirmation of recombinant DNA by sequencing.

Choose the correct answer from the options given below :

QUESTION ID:79

Hydrophobic nature of amino acids affects the tertiary structure of proteins. Which of the following option shows the given amino acids in decreasing order of their hydrophobic character?

A. Leucine
B. Phenylalanine
C. Glycine
D. Histidine
E. Lysine

Choose the correct answer from the options given below:

QUESTION ID:80

Given below are two statements:

Statement I: Cooperativity in receptor - ligand interaction causes large change in receptor activation with small change in ligand concentration.
Statement II: In amplification, the enzyme associated with signal receptor is activated which in turn activates many downstream enzymes in a so called enzyme cascade.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:81

Given below are two statements:

Statement I: Phototrophs and chemotrophs derive their energy from sunlight and chemical fuels, respectively.
Statement II: Phototrophs and chemotrophs cannot be autotrophs but only heterotrophs.

In the light of the above statements, choose the correct answer from the options given below :

QUESTION ID:82

Given below are two statements:

Statement I: In all naturally occurring 20 amino acids, both carboxyl and amino groups are bonded to the Î±- carbon.
Statement II: According to organic chemistry IUPAC nomenclature, a-carbon is also the C-1 carbon of an amino acid.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:83

Given below are two statements:

Statement I: The peptide bond Cα-C-N-Cα present in proteins is rigid and planar.
Statement II: Proteins are highly dynamic and undergo large conformational changes.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:84

Given below are two statements:

Statement I: Major Histocompatibility Complex (MHC) is present on the cell surface of T-cells for antigen recognition.
Statement II: During organ transplantation, the major Histocompatibility Complex (MHC) is involved in allograft rejection.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:85

Given below are two statements:

Statement I: Chymotrypsin hydrolyzes peptide bond through the formation of a transient covalent acyl- enzyme intermediate.
Statement II: This type of mechanism in enzyme catalysis is operative in all the enzymes in biology.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:86

Given below are two statements:

Statement I: Sanger's chain termination method is used for sequencing of a single stranded DNA by using nucleotides and short DNA stretches.
Statement II: Sanger's protein sequencing method uses 1-fluoro-2, 4-dinitrobenzene, dansyl chloride and nucleosides for protein sequencing.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:87

What is true about bacterial DNA-dependent RNA Polymerase.

A. It is an oligomer of approximately 400KDa.
B. Its beta(β) subunit together with Mg2+ converts ribonucleotides into RNA.
C. Î±-amanitin strongly inhibits the enzyme.
D. The enzyme can also form DNA from RNA.

Choose the most appropriate answer from the options given below :

QUESTION ID:88

For the respiration of two proteins with same molecular weight, which of the following techniques could be used:

A. SDS-PAGE
B. 2D-SDS-PAGE
C. Mass spectrometry with liquid chromatography.
D. Gel filtration.
E. Gel filtration and SDS-PAGE.

Choose the correct answer from the options given below:

QUESTION ID:89

Hydrophobic effect has a major role in the stabilization of three dimensional structure of proteins. Which of the following amino acids form part of this effect:

A. Glycine, Alanine, leucine
B. Valine. Methionine. Isoleucine
C. Tryptophan. Tyrosine, Phenylalanine
D. Tryptophan, Proline, Phenylalanine
E. Tyrosine, Serine, lysine

Choose the correct answer from the options given below:

QUESTION ID:90

Sickle cell anemia causes sickling of the RBCs. Which of the following is not correct for the disease?

A. Haemoglobin forms large aggregates.
B. Disease does not affect the oxyhaemoglobin but decreases solubility of deoxyhaemoglobin.
C. The enhanced aggregation propensity is due to the hydrophobic effect of the underlying mutation.
D. The patients are more prone to malaria.
E. The disease is not curable

Choose the correct answer from the options given below:

QUESTION ID:91

Which of the following statements together describe the integral membrane proteins:

A. Form main component of the biological membranes
B. Are soluble in aqueous solutions
C. Mostly composed of polar amino acids and are lysine rich.
D. Are soluble in sodium dodecyl sulphate (SDS)
E. Form aggregates in aqueous solutions.

Choose the correct answer from the option given below :

QUESTION ID:92

Which of the following are true for Nucleosomes ?

A. Protein bodies
B. Protein - DNA complexes
C. Nucleic acids are covalently linked to proteins
D. Protein octamers are wrapped with approximately 200bp of DNA.
E. 10 nm fibers for DNA packing

Choose the correct answer from the options given below :

QUESTION ID:93

Restriction enzymes are the enzymes that :

A. catalyze restricted reactions in DNA replication.
B. are essential tools in biotechnology
C. were discovered by Sanger and Pauling
D. Cut DNA specifically
E. are the immune defense mechanism in bacteria.

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QUESTION ID:100

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