Previous Year Questions

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TLS Online TPP Program

QUESTION ID:1

Identify the correct preposition to make a meaningful sentence.

Mirror neurons first came _____ light in the 1980s.

QUESTION ID:2

Identify the meaning of the underline idiom from the options given :

Radha's brother strained every nerve to enable her to get admission in Medical college.

QUESTION ID:3

Choose the correct option to make a meaningful sentence. His secretary _____ five orphanages by today evening.

QUESTION ID:4

Identify synonym for the underlined word in the sentence.

Aman's parents are happy that the couple is trying to find an amicable​ solution to their problems.

QUESTION ID:5

Pick out the correctly spelt word.

QUESTION ID:6

Identify the correct active voice for the sentence given below :

You are requested not to switch on the bulb.

QUESTION ID:7

Identify the correct direct speech for the sentence given below

The Forbes told that it was not responsible for any information published in the magazine.

QUESTION ID:8

Give below are four sentences in jumbled order. Select the option that gives their correct order.

A. The structure of the building depends on the purpose for which it is erected.

B. People who design a building keep in mind the purpose for which it is being erected.

C. Humans erect buildings for various purposes.

D. One building may require strength, another may require comfort, and a third may require space.


Choose the correct answer from the options given below :

QUESTION ID:9

From among the four options given, choose the one which is a grammatically correct sentence.

QUESTION ID:10

Find out which part of the sentence has an error. If there is no error, mark option 4. (DROP)

QUESTION ID:11

In 1985, the Government of India launched a special vaccination programme called :

QUESTION ID:12

Match List I with List II

List - IList - II
Indian NationalsMagsaysay winners under specific category
A. Verghese KurienI. Government Service
B. Boobli Geogre VergheseII. Emergent Leadership
C. James Michale LyndohIII. Journalism & Creative Arts
D. Kulandei FranicsIV. Community Leadership
Choose the correct answer from the options given below :

QUESTION ID:13

Match List- I with List- II

List - I (Type Hydrogen)List - II (Explanation)
A. GreenI. Generated through electrolysis powered by nuclear energy
B. BlueII. Generated from natural gas but the carbon dioxide is not captured.
C. GreyIII. Generated by splitting natural gas by SMR and ATR method, Carbon dioxide is captured.
D. PinkIV. Generated by electrolysis of water using renewable energy.

Choose the correct answer from the options given below:

QUESTION ID:14

Cartographers are those who make :

QUESTION ID:15

In 2003, space shuttle Columbia which carried Indian origin astronaut Kalpana Chawla, an Israeli and five other members disintegrated upon its re-entry to the Earth's atmosphere.

Name the Israeli astronaut.

QUESTION ID:16

Find the next alphabets - VULHI, TSMJK, RQNIM, POONO, -----

QUESTION ID:17

Aman, Balwinder, Chetan, Mahesh, Pradeep, Deepti are standing in a circle facing centre. Balwinder is in between Deepti and Chetan. Aman is in between Pradeep and Mahesh. Deepti is to the left of Mahesh. Who is between Balwinder and Mahesh?

QUESTION ID:18

Which does not belong with the others ?

(i) Contents

(ii) Chapter

(iii) Bibliography

(iv) Research Thesis

QUESTION ID:19

Meena lives in Mumbai and has a house on the western beach. Her younger cousin Rakesh lives in a small town near Delhi. Rakesh is a frequent visitor to Mumbai and stays with Meena. Meena has visited Rakesh's house only once in the past 3 years.

(i) Rakesh likes Meena more than Meena likes Rakesh.

(ii) Meena is elder to Rakesh.

(iii) Meena does not like small towns.

(iv) Rakesh wants to buy house on the beach.

QUESTION ID:20

Find the missing number,

7, 8, 15, 34, 71, 132. _____

QUESTION ID:21

Arrange the following fractions (A-E) in their ascending order.

A. 5/8

B. 7/12

C. 13/16

D. 16/29

E. 3/4

Choose the correct answer from the options given below:

QUESTION ID:22

A mixture contains alcohol and water in the ratio 4:3. If 5 liters of water is added to the mixture, the ratio becomes 4:5. The quantity of alcohol in the given mixture (in liters) is :

QUESTION ID:23

The value of ​ : is approximately equal to

QUESTION ID:24

If , then 

QUESTION ID:25

If the difference between compound and simple interest on a certain sum of money for 3 years at 2% per annum is ₹ 604, then what is the sum?

QUESTION ID:26

Which of the following technique is used for tracing change in intracellular location of proteins and metabolites.

QUESTION ID:27

A specific protein required for infecting a host by corona virus is known as:

QUESTION ID:28

The most common initial step to separate water soluble proteins from insoluble cellular material is-

QUESTION ID:29

The pH at which net charge of protein becomes zero under an electrical field at room temperature is known as

QUESTION ID:30

The microscope that converts slight difference in the refractive index and cell density into easily observed difference in the light intensity is known as-

QUESTION ID:31

Which of the following Histone protein found in chromatin has high Lysine content?

QUESTION ID:32

Which of the following techniques may be used for identifying a regulatory protein that acts by binding to specific sequence of DNA?

QUESTION ID:33

Which of the following disease in humans is caused due to expanded microsatellite repeats?

QUESTION ID:34

Which of the following disease is associated with Philadelphia chromosome?

QUESTION ID:35

A classification system that groups organisms together based on the similarity of their observable characteristics is known as-

QUESTION ID:36

A class of Immunoglobulin present in the serum which neutralizes toxins, activates complements and crosses the placenta to protect the fetus and neonate is

QUESTION ID:37

Blood group antigen differs in their

QUESTION ID:38

The replication on template strand always proceeds in 5′ to 3′ direction. If the sequence of template strand is 5′ATCCCT3′, how would the correct sequence of newly synthesized strand of DNA be read?

QUESTION ID:39

Which of the following condition is NOT essential to maintain Hardy-Weinberg equilibrium in a population?

QUESTION ID:40

Bacteria produce an enzyme methylase which mainly plays a role in

QUESTION ID:41

In anaerobic conditions, yeast consumes more glucose than in the presence of aerobic environment. This phenomenon is known as-

QUESTION ID:42

Which DNA repair system is affected in Lynch syndrome?

QUESTION ID:43

Which of the following animal has a pseudocoel?

QUESTION ID:44

Which of the following is NOT a characteristic feature of bony fishes?

QUESTION ID:45

The method which was first developed for gene mapping in bacteria was

QUESTION ID:46

The gold standard method used for the detection of SARS-CoV-2 infection is

QUESTION ID:47

Which one of the following phytochemicals produced in plants defend against herbivores?

QUESTION ID:48

The rate of oxygen production is enhanced when there is operation of

QUESTION ID:49

The primary acceptor of CO2​ in C4​ plants is

QUESTION ID:50

The prokaryotic microorganism which fixes atmospheric nitrogen in symbiotic association under aerobic condition in aquatic ferns is-

QUESTION ID:51

Which of the following is not a vitamin?

QUESTION ID:52

A cloning vector may not contain

QUESTION ID:53

A lambda phage genome has a length of

QUESTION ID:54

Chemically synthesized linker molecules containing recognition sequences of specific restriction endonucleases for creation of cohesive ends in blunt ended DNA fragments are generally

QUESTION ID:55

Which one of the following is autoimmune disease?

QUESTION ID:56

In which of the following plants, the gametophyte does not represent an independent free living generation?

QUESTION ID:57

Which of the following statement is true about Gymnosperms?

QUESTION ID:58

Gaucher disease is a genetic disorder which is associated with

QUESTION ID:59

Hematopoietic stem cells are found in

QUESTION ID:60

Which of the following vaccine does not provide life time protection?

QUESTION ID:61

The formation of endosperm before fertilization is a characteristic of

QUESTION ID:62

Heterospory is not found in

QUESTION ID:63

Diagnostic test used to detect Human Immunodeficiency Virus is

QUESTION ID:64

Which one of the following antibody can cross placental barrier?

QUESTION ID:65

Trypan blue assay is used for the:

QUESTION ID:66

Match List- I with List- II

List-I (Enzymes)List-II (Function)
A. Histone acetyl transferaseI. DNA replication
B. Cyclin dependent kinaseII. Chromatin remodeling
C. α-antitrypsinIII. Cell cycle regulation
D. TopoisomeraseIV. Emphysema

Choose the correct answer from the options given below:

QUESTION ID:67

Match List- I with List- II

List-I (Animal)List-II (Larva)
A. AnnelidsI. Veliger
B. InsectsII. Trochophore
C. MolluscesIII. Ammocoetes
D. CyclostomesIV. Catterpillar

Choose the correct answer from the options given below:

QUESTION ID:68

Match List- I with List- II

List-I (Hormone)List-II (Function)
A. Epinephrine in liverI. Conversion of glycogen to glucose-1 phosphate
B. FSHII. Increased conversion of glycogen to glucose
C. VasopressinIII. Increase synthesis of estrogen
D. Epinephrine in skeletal muscleIV. Reabsorption of water

Choose the correct answer from the options given below:

QUESTION ID:69

Match List- I with List- II

List-I (Nitrogenous bases)List-II (Deaminated product)
A. CytosineI. Thymine
B. 5-methyl-cytosineII. Xanthine
C. AdenineIII. Uracil
D. GuanineIV. Hypoxanthine

Choose the correct answer from the options given below:

QUESTION ID:70

Match List- I with List- II

List-I (Compound)List-II (Function)
A. DolicholI. Blood clotting factor
B. Vitamin-KII. Antioxidant
C. Vitamin-EIII. Anticoagulant
D. WarfarinIV. Sugar carrier

Choose the correct answer from the options given below:

QUESTION ID:71

Match List- I with List- II

List-I (Cell type)List-II (Function)
A. MacrophagesI. Antibody production
B. B-cellsII. Phagocytosis
C. Cytotoxic T-cellsIII. Interact with macrophages and secret cytokines
D. Helper T-cellsIV. Interact with infected host cells

Choose the correct answer from the options given below:

QUESTION ID:72

Match List I with List II

List-I (Name of Scientists)List-II (Discoveries)
A. Avery, Macleod and McCartyI. Complementation analysis
B. Edward JennerII. Law of equivalence of bases
C. Erwin ChargaffIII. Chemical basis of heredity
D. Seymour BenzerIV. Vaccine

Choose the correct answer from the options given below:

QUESTION ID:73

Given below are two statements:

Statement I : The application of herbicides to kill unwanted plants is widespread in agriculture.

Statement II : DCMU act by blocking electron flow at the quinone acceptors of photosystem by competing for the binding site of plastoquinone.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:74

Given below are two statements:

Statement I: In prokaryotes all types of RNAs are transcrilbed by the holoenzyme, that consists of several polypeptides (Two α, One β, & One β' and one σ).

Statement II: The start signals on DNA are called promoters and represent the initial binding site for the RNA polymerase.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:75

Given below are two statements:

Statement I: The Glycolytic pathway is the only route available for the oxidation of sugars in plant cells.

Statement II: In Pentose phosphate pathway, the complete oxidation of one glucose-6-phosphate molecule to CO2 results in production of 12 NADPH molecules.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:76

Given below are two statements:
Statement I: Telomeres are sequences at the end of eukaryotic chromosomes which helps in stabilizing the chromosome.
Statement II: Telomeres end with multiple repeated sequences in the form of (TTAGGG)n in humans.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:77

Given below are two statements:
Statement I: In agarose gel electrophoresis, the large pore sizes of the low concentration gels makes possible the separation of very large molecules.
Statement II: In agarose gel electrophoresis, the small pore sizes of the high concentration gels makes possible the separation of large molecules.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:78

Given below are two statements:
Statement I: Mycorrhiza is a symbiotic association between cyanobacteria with the roots of higher plants.
Statement II: Mycorrhizal association is important for nutrient acquisition in plants under limited condition.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:79

Given below are two statements:
Statement I: Apoptosis is a genetically regulated process occurring in specific tissues during development and disease by which cell destroy itself.
Statement II: Apoptosis is regulated by intracellular signals generated from many secreted cells, cell surface, protein hormones as well as many environmental stresses.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:80

Given below are two statements:
Statement I: In C4 cycle fixation of CO2 by the carboxylation of phosphoenol pyruvate in the mesophyll cells results in conversion to malate or aspartate.
Statement II: The transport of C4 acids to the bundle sheath cells leads to decarboxylation and generation of CO2, which is finally reduced into carbohydrates via Calvin cycle.

In the light of the above statements, choose the most appropriate answer from the options given below:

QUESTION ID:81

Establishment of mammalian cell culture involves the following steps.

A. Culture of primary cells
B. Subculture of primary cells
C. Separation of cells from tissue by mechanical or enzymatic method
D. Culture of secondary cells
E. Subculture of secondary cells

Choose the correct answer from the options given below:

QUESTION ID:82

The steps involved in bacterial translation are

A. Activation of amino acids
B. Initiation of polypeptide synthesis
C. Aminoacylation tRNA
D. Peptide bond formation
E. Termination of polypeptide

Choose the correct answer from the options given below:

QUESTION ID:83

The sequential steps involved in prophase I of meiosis are

A. Chromosome condensation
B. Terminalization of chiasmata
C. Formation of tetrad of bivalents (four strand)
D. Pairing of homologous chromosomes
E. Genetic recombination

Choose the correct answer from the options given below:

QUESTION ID:84

Arrange the following discoveries in increasing order

A. Greger John Mendel discovered the basic principles of Genetics
B. Charles Darwin published a book on origin of species
C. Watson and Crick deciphered DNA structure
D. Friedrich Miescher identified Nuclein
E. Oswald Avery identified DNA as the transforming principle

Choose the correct answer from the options given below:

QUESTION ID:85

Arrange the following in order of their action

A. G1 cyclin CDK Complex
B. APC-cdh1
C. S Phase cyclin CDK Complex
D. MPF
E. APC-cdc20

Choose the correct answer from the options given below:

QUESTION ID:86

Identify the correct order of signal transduction pathway

A. Binding of ligands to cell surface receptor
B. Termination of signal
C. Generation of intracellular second messenger
D. Intracellular signaling cascade
E. Effector response

Choose the correct answer from the options given below:

QUESTION ID:87

The nuceloplasmic index, where the nuclear mass and cytoplasmic mass of the cells are in the state of optimum equilibrium depends upon

A. Nuclear volume
B. Cell volume
C. Nuclear mass
D. Cytoplasmic mass
E. Centrioles number

Choose the correct answer from the options given below:

QUESTION ID:88

Identify the inhibitory neurotransmitters from the following:

A. Glutamate
B. Aspartate
C. Cysteine
D. Glycine
E. GABA

Choose the correct answer from the options given below:

QUESTION ID:89

The function of a gene depends on expression of

A. DNA
B. RNA
C. Protein
D. Metabolite
E. Lipid

Choose the correct answer from the options given below:

QUESTION ID:90

Identify the features of cancer cells

A. Rapid cell growth and division
B. Reduced cell growth and division
C. Loss of normal control of cell division
D. Reduced angiogenesis
E. Utilize glucose at reduced rate

Choose the correct answer from the options given below:

QUESTION ID:91

Identify the methods to measure apoptosis in-vitro in mammalian cell culture

A. MTT assay
B. LC MS
C. NMR
D. Crystal violet assay
E. PAGE

Choose the correct answer from the options given below:

QUESTION ID:92

Identify the tumor suppressor genes from the following

A. Ras
B. Raf
C. PTEN
D. Myc
E. p53

Choose the correct answer from the options given below:

QUESTION ID:93

Which of the following organizations are involved in Covaxin production in India.

A. DBT
B. CSIR-CDRI
C. ICMR-NIV
D. Bharat Biotech
E. Bharat Serum

Choose the correct answer from the options given below:

QUESTION ID:94

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: Bateson & Punett showed that the linked genes do not obey Mendel’s law of independent assortment.

Reason R: The Dihybrid test cross ratio for closely linked genes produced 50% parental and 50% recombinant types of progeny.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:95

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: Oligosaccharides with unique structures are components of a variety of glycoproteins and glycolipids on the outer surface of plasma membranes.

Reason R: The influenza virus infects animal cells by binding to the cell surface glycoproteins as first step of infection.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:96

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: Each Dideoxynucleotide used in Sanger’s method of DNA sequencing can be linked to a fluorescent molecule that gives all the fragments terminating at that nucleotide of particular colour.

Reason R: The DNA sequence is read by determining the sequence of colour in the peak as they pass through the detector.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:97

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: Polyploid species of common bread wheat have evolved by hybridization followed by chromosome doubling in interspecific hybrids by treatment with colchicine.

Reason R: Colchicine induces gigantism in allopolyploid species of bread wheat.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:98

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A: The lacZ gene is present of pUC cloning vectors as the selectable marker by which recombinants may be selected through insertional inactivation of lacZ gene.

Reason R: IPTG acts as gratuitous inducer of lacZ genes due to which recombinants produced in pUC vectors may be selected by Blue-white screening.

In the light of the above statements, choose the correct answer from the options given below:

QUESTION ID:99

Match List I with List II

List-I (Group of Organisms/Plants)List-II (Grouped as)
A. Bacteria and Blue-Green AlgaeI. Tracheophyta
B. Bryophytes and PteridophytesII. Spermatophyta
C. Pteridophytes and GymnospermsIII. Monera
D. Angiosperms and GymnospermsIV. Embryophyta

Choose the correct answer from the options given below:


QUESTION ID:100

Match List I with List II

List-I (Plants)List-II (Economic Importance)
A. Rauwolfia serpentinaI. Insect repellents
B. Vinca roseaII. Tooth paste
C. Schizyzium aromaticumIII. Blood Pressure
D. Azadirachta indicaIV. Cancer

Choose the correct answer from the options given below: