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Previous Year Questions

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QUESTION ID:1

Read the passage carefully and answer the question.

All over the world the wild fauna has been whittled down steadily and remorselessly, and many lovely and interesting animals have been so reduced in numbers that, without protection and help, they can never re-establish themselves. If they cannot find sanctuary where they can live and breed undisturbed, their numbers will dwindle until they join the dodo, the quagga, and the great auk on the long list of extinct creatures.

Of course, in the last decade or so much has been done for the protection of wild life: sanctuaries and reserves have been started, and the reintroduction of species into areas where it had become extinct is taking place. In Canada, for instance, beavers are now being reintroduced into certain areas by means of aero plane.

But although much is being done, there is still a very great deal to do. Unfortunately, the majority of useful work in animal preservation has been done mainly for animals which are of some economic importance to man and there are many obscure species of no economic importance which, although they are protected on paper, are in actual fact being allowed to die out because nobody, except a few interested zoologists, considers them important enough to spend money on.

As mankind increases year by year, and as he spreads farther over the globe burning and destroying, it is some small comfort to know that there are certain private individuals and some institutions who consider that the work of trying to save and give sanctuary to these harried animals is of some importance. It is important for many reasons, but perhaps the best of them is this: man for all his genius, cannot create a species, nor can he recreate one he has destroyed. So until we consider animal life to be worthy of the consideration and reverence we bestow upon old books and pictures and historic monuments, there will always be the animal refugee living a precarious life on the edge of extermination, dependent for existence on the charity of a few human beings.


Which of the following would prove most effective in preserving wild life? 

QUESTION ID:2

Animal species should be preserved mainly because 

QUESTION ID:3

What attitude towards wild life does the author think most appropriate? 

QUESTION ID:4

Which of the following types of animals does man chiefly protect? 

QUESTION ID:5

The wild life is about to become extinct mainly because: 

QUESTION ID:6

Synonym of the word 'CELESTIAL' is: 

QUESTION ID:7

Fill in the blanks with appropriate prepositions from the following options: 

India is one of the richest countries _________ the world in terms of biodiversity. Due __________ anthropogenic activities, many species have lost their habitat and even become extent. International Union _________  conservation _________ nature and natural resources has categorized with flora and fauna into eight categories. 

QUESTION ID:8

Fill in the blank with suitable word from the options given below: 

Light _________ in a straight line. 

QUESTION ID:9

Which word is not the synonym of 'Colossal'. 

QUESTION ID:10

Correct the sentence by replacing the under lined phrase: 

Those who are indecisive can be readily persuading to change their mind again. 

QUESTION ID:11

Find the value of

16 ÷ 4 x 4 - 3 + 2

QUESTION ID:12

A cardboard box of dimensions 80 cm x 60 cm × 75 cm is to be constructed. Find the cardboard required (in m²) for the box. 

QUESTION ID:13

A fruit vendor bought apples for ₹ 6,000. He sold 40% stock with 25% profit, another 40% stock with 15% profit and the rest with 10% profit. Find his profit percentage. 

QUESTION ID:14

Out of the three numbers, first number is twice of the second number and thrice of the third number. The average of their reciprocals is 1/6. The numbers are: 

QUESTION ID:15

A train running at 90 km/h crosses a 400 m long another train running towards it on parallel tracks at 80 km/h in 18 seconds. How much time will it take to pass a 450 m long tunnel? 

QUESTION ID:16

A is facing the east direction. If he turns 270° he will face: 

QUESTION ID:17

The tenth term of the given series 4Z, 5Y, 6X, 7W, ________ will be: 

QUESTION ID:18

In the given figure find the value of x (O is the center of the given circle? 


QUESTION ID:19

ZOOM is coded as 138. The code 72 will be: 

QUESTION ID:20

2, 7, 14, 23, 34, __________ .
 
Complete the series choosing appropriate option: 

QUESTION ID:21

The first general election in India was held in 

QUESTION ID:22

Match List I with List II 

LIST I (Monuments)LIST II (Country)
A. Imperial palaceI. France
B. Opera HouseII. Denmark
C. Eiffel TowerIII. Australia
D. Kindu DiskIV. Japan

Choose the correct answer from the options given below: 

QUESTION ID:23

When was Jana-Gana-Mana (which later became 'National Anthem' of India) first sung and where? 

QUESTION ID:24

Given below are two statements: 
Statement I: Lord Mountbatten was the Viceroy when Simla conference took place. 
Statement II: Indian Navy Revolt, 1946 took place when the Indian Sailors in the Royal Indian Navy at  Bombay and Karachi rose against the Government. 

In the light of the above statements, choose the most appropriate answer from the options given below: 

QUESTION ID:25

The gas which is present in both natural gas and bio-gas is _________. 

QUESTION ID:26

Which of the following statement is true about nucleoside? 

QUESTION ID:27

Which of the following is an amino acid? 

QUESTION ID:28

Which of the following antibodies can cross the placenta? 

QUESTION ID:29

What is the net charge of glutamate at pH 7? 

QUESTION ID:30

Non-active protein part of an enzyme that requires cofactor for activation is 

QUESTION ID:31

Insulin-dependent glucose uptake by adipose tissue is the result of 

QUESTION ID:32

Which of the following motor proteins is involved in intracellular transport along microtubules? (DROP)

QUESTION ID:33

Which of the following cellular organelle is involved in Tay-Sachs disease (TSD)? 

QUESTION ID:34

During DNA repair, which of the following enzymes is involved in phosphodiester bond formation? 

QUESTION ID:35

What is not true about endotoxin? (DROP) 

QUESTION ID:36

Upon re-exposure to a previous pathogen, which immune response will be most likely the fastest one? 

QUESTION ID:37

What is true about MHC class II? 

QUESTION ID:38

Patients with Galactosemia are advised not to take dairy products because 

QUESTION ID:39

Glycerol kinase is not expressed in 

QUESTION ID:40

In prolonged starvation, a minimum glucose level is maintained for supplying glucose to brain and RBCs. This is achieved by 

QUESTION ID:41

Which of the following is a cis-acting element? 

QUESTION ID:42

Oligomycin blocks the electron transport chain by 

QUESTION ID:43

How many ATP molecules are produced for each molecule of FADH2 oxidized via the respiratory chain?

QUESTION ID:44

In E. coli, pur repressor regulates the expression of more genes as compared to lac repressor because 

QUESTION ID:45

Glomerular filtration rate is determined by creatinine clearance test and inulin clearance test. Which of the following statements is true about GFR? 

QUESTION ID:46

In hepatocellular disease 

QUESTION ID:47

AST/ALT ratio is decreased in 

QUESTION ID:48

At 50% saturation, each Hb molecule has __________ bound. 

QUESTION ID:49

Internal respiration occurs in 

QUESTION ID:50

Which of the following factors affects the affinity of hemoglobin for oxygen? 

QUESTION ID:51

To solve the mystery of spoilage of wine, Pasteur observed yeast and bacteria in the fermented grape juice (wine). Through a series of experiments, he proved 

QUESTION ID:52

Penicillin, the first found natural antibiotic acts by 

QUESTION ID:53

Some microbes survive or grow at very high temperatures because of 

QUESTION ID:54

Who was the first scientist to prove the Germ Theory of disease? 

QUESTION ID:55

In the polarized epithelial cells of PCT of kidney, the difference in apical and basolateral membrane is maintained by 

QUESTION ID:56

If a double-stranded DNA has 30% Guanine, what will be the percentage of Adenine? 

QUESTION ID:57

Recognition sequence of Restriction Endonuclease: BamH1 is 

QUESTION ID:58

Which of the following statements is not correct? 

QUESTION ID:59

In hypothetical enzymatic reaction 


the end product C is allosteric inhibitor of Enzyme 1. C will also regulate the activity of Enzyme 1 by 

QUESTION ID:60

Which of the following elements binds to protein and forms a critical DNA binding motif? 

QUESTION ID:61

Kwashiorkor disease is linked with insufficient intake of 

QUESTION ID:62

Which of the following groups consists of only aromatic compounds? 

QUESTION ID:63

Which of the following statements is true? 

QUESTION ID:64

Molarity is a better way of expressing the concentration of solution as compared to gram percent especially 

QUESTION ID:65

Lineweaver-Burk plot of a viral enzyme in presence of two drugs is shown here. Which of the following statements regarding the actions of drugs is true? 

A. Drug A acts as competitive inhibitor. 

B. Drug B acts as competitive inhibitor. 

C. Drug A acts as non-competitive inhibitor. 

D. Drug B acts as non-competitive inhibitor. 

QUESTION ID:66

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): During starvation, when ẞ-oxidation of fatty acids is predominant in liver, acetyl CoA formed  enters the citric acid cycle.
Reason (R): Acetyl CoA must combine with oxaloacetate to gain entry to the citric acid cycle. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:67

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Maternal blood O2 saturation is quite low in placenta. Even at this lower saturation, O2 is readily transferred to fetal blood. 
Reason (R): Fetal hemoglobin binds BPG less strongly, thus having higher affinity for O2 as compared to adult hemoglobin. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:68

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Insulin acts on multiple tissues as compared to glucagon. 
Reason (R): Insulin is lipid soluble and easily passes through cell membrane of target cells. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:69

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Oxidative phosphorylation- the synthesis of ATP from ADP and inorganic phosphate requires energy. 
Reason (R): The energy for oxidative phosphorylation is provided by the proton gradient generated during electron transport chain. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:70

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Glucose gets trapped in extrahepatic tissues and does not move out of the cell. 
Reason (R): Glucokinase irreversibly phosphorylates glucose to glucose-6-phosphate in extrahepatic tissues. 
There are no transporters for glucose-6-phosphate and glucose gets trapped in extrahepatic tissues. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:71

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Salt is added as a preservative for storage of meat. 
Reason (R): Salt creates hypertonic environment and most bacteria cannot grow in hypertonic media. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:72

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R): 
Assertion (A): Restriction endonuclease cleave the foreign viral DNA inside the bacterial cell, but bacterial DNA is protected from Restriction Endonuclease attack. 
Reason (R): Bacterial DNA does not contain recognition sequence of restriction endonuclease. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:73

Enzymes involved in urea biosynthesis from ammonia are listed below. Arrange these in order of their actions : 
A. Arginase 
B. Ornithine carbonyl transferase 
C. Argininosuccinate lyase 
D. Carbamoyl phosphate synthetase I 
E. Argininosuccinate synthetase 

Choose the correct answer from the options given below. 

QUESTION ID:74

Arrange the stages of infection process as they occur: 
A. Evasion from host defence mechanism 
B. Entry of pathogen 
C. Damage to host cell 
D. Exit from the host
 
Choose the correct answer from the options given below. 

QUESTION ID:75

Arrange the following stages of bacterial growth curve chronologically: 
A. Lag phase 
B. Stationary phase 
C. Log phase 
D. Death phase
 
Choose the correct answer from the options given below. 

QUESTION ID:76

Arrange the steps in processing and presenting of an endogenous antigen by an infected body cell as they occur: 
A. Binding of peptide fragments to MHC-I molecule 
B. Digestion of antigen into peptide fragments 
C. Synthesis of MHC-I molecules 
D. Packaging of antigen-MHC-I molecule 
E. Insertion of antigen-MHC-I complex into plasma membrane 

Choose the correct answer from the options given below. 

QUESTION ID:77

Gene expression is controlled at various stages written below. Arrange these stages in chronological order: 
A. Transcription 
B. Translation 
C. Post-transcription 
D. Epigenetic regulation 
E. Post-translation 

Choose the correct answer from the options given below. 

QUESTION ID:78

Proteins involved in DNA replication are written below. Arrange them chronologically in terms of function: 
A. DNA polymerase I 
B. DNA polymerase III 
C. Helicase 
D. Ligase 
E. Primase 

Choose the correct answer from the options given below. 

QUESTION ID:79

Arrange the following steps of cell signalling in chronological order: 
A. Reception 
B. Generation of signal 
C. Response 
D. Transduction 

Choose the correct answer from the options given below. 

QUESTION ID:80

Given below are two statements: 
Statement-I: Histone acetylation is generally associated with decrease in gene transcription.
Statement-II: Acetylation occurs on lysine residues in the N-terminal tails of histones. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:81

Given below are two statements: 
Statement-I: Mutation in the middle of a gene ene that creates stop codon is called frameshift mutation. 
Statement-II: Frameshift mutation can be a point mutation. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:82

Given below are two statements: 
Statement-I: Weak interactions like hydrogen bonds and salt bridges stabilize protein folding. 
Statement-II: Protein folding is assisted by chaperones.
 
In the light of the above statements. choose the most appropriate answer from the options given below. 

QUESTION ID:83

Given below are two statements: 
Statement-I: Enzymes lower the activation energy of reactions. 
Statement-II: The presence of an enzyme has no effect on Keq.
 
In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:84

Given below are two statements: 
Statement-I: 146 base pairs of DNA are wrapped around the histone octamer to form a nucleosome. 
Statement-II: Nucleosomes play important role in gene expression.
 
In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:85

Given below are two statements: 
Statement-I: Ammonia is produced during catabolism of amino acids in muscle cells. 
Statement-II: In muscle cells, ammonia is converted to urea and then excreted through kidney. 

In the light of the above statements, choose the most appropriate answer from the options given below. 

QUESTION ID:86

Given below are two statements: 
Statement-I: Cyanide results in cellular hypoxia. 
Statement-II: The tight coupling of electron transport and phosphorylation is uncoupled by cyanide. 

In the light of the above statements. choose the most appropriate answer from the options given below. 

QUESTION ID:87

What is true about steroid hormones? 
A. Steroid hormones bind to specific receptors. 
B. Steroid hormones bind to DNA to control gene expression. 
C. Steroid hormones travel to distant tissues through blood.
 
Choose the correct answer from the options given below. 

QUESTION ID:88

Which of the following statements is true about histones? 
A. Histones are rich in acidic amino acids. 
B. Histones are rich in basic amino acids. 
C. Histones are important for stabilizing single-stranded DNA. 
D. Histones bind to DNA to form chromatin. 

Choose the correct answer from the options given below. 

QUESTION ID:89

Resting membrane potential is conducted by 
A. active transport 
B. selective permeability of phospholipid bilayer 
C. passive diffusion across lipid bilayer 
D. differential distribution of ions across membrane 

Choose the correct answer from the options given below. 

QUESTION ID:90

Which of the following proteins do not belong to the group of chromoproteins? 
A. Fibroin 
B. Haemoglobin 
C. Keratin 
D. Cytochromes 
E. Flavoproteins 

Choose the correct answer from the options given below. 

QUESTION ID:91

What information about protein can be derived most accurately from gene sequence? 
A. Primary structure of protein 
B. Function of protein 
C. Secondary structure of protein 
D. Three-dimensional structure of protein 

Choose the correct answer from the options given below. 

QUESTION ID:92

Two proteins X (Mol wt. 20 kD, pI 6.3) and Y (Mol. wt. 90 kD, pI 6.4) can be separated by which of the following techniques? 
A. Gel filtration 
B. Ion-exchange chromatography 
C. Isoelectric focussing 
D. SDS-PAGE 

Choose the correct answer from the options given below. 

QUESTION ID:93

Which of the following techniques can be used for analysis of gene expression? 
A. Northern blotting 
B. Southern blotting 
C. Western blotting 
D. qRTPCR 
E. RNA sequence
 
Choose the correct answer from the options given below. 

QUESTION ID:94

Match List I with List II 

LIST ILIST II
A. Vitamin AI. Rickets
B. Vitamin KII. Excessive bleeding
C. Vitamin CIII. Night blindness
D. Vitamin DIV. Scurvy

Choose the correct answer from the options given below: 

QUESTION ID:95

Match List I with List II 

LIST ILIST II
A. LeucineI. Phosphorylated by kinase
B. SerineII. Negatively charged R group
C. GlutamateIII. Non-polar, Aliphatic R group
D. TryptophanIV. Aromatic R group

Choose the correct answer from the options given below: 

QUESTION ID:96

Match List I with List II 

LIST ILIST II
A. VLDLI. Transport cholesterol from peripheral tissues to liver
B. ChylomicronsII. Transport cholesterol from liver to other tissues
C. HDLIII. Movement of dietary triacylglycerol to various tissues
D. LDLIV. Transport of endogenously synthesized triacylglycerols

Choose the correct answer from the options given below: 

QUESTION ID:97

Match List I with List II 

LIST ILIST II
A. DNA methylationI. Increase accessibility of DNA sequence
B. Histone acetylationII. Gene silencing
C. ATP-dependent chromatin remodellingIII. Occurs on lysine residues of histones
D. NucleosomeIV. Barrier for transcription

Choose the correct answer from the options given below: 

QUESTION ID:98

Match List I with List II 

LIST ILIST II
A. DNA polymerase Î²I. Primase
B. DNA polymerase Î´II. DNA repair
C. DNA polymerase Î±III. Mitochondrial DNA replication
D. DNA polymerase Î³IV. Leading and lagging strands of DNA

Choose the correct answer from the options given below: DNA polymerase 

QUESTION ID:99

Match List I with List II 

LIST ILIST II
A. Cyclin D/CDK4I. Triggers cell death
B. Cyclin E/CDK2II. Transition from G2 to M
C. Cyclin B/CDK1III. Initiation of DNA synthesis
D. p53IV. G1 checkpoint

Choose the correct answer from the options given below: 

QUESTION ID:100

Match List I with List II 

LIST ILIST II
A. GlycogenI. Cell wall of plants
B. StarchII. Carbohydrate storage in animals
C. CelluloseIII. Carbohydrate storage in plants
D. ChitinIV. Cell wall of fungi

Choose the correct answer from the options given below: