Previous Year Questions

QUESTION ID:2

The science of collecting small molecules in a given cell under a specific set of conditions is called:

QUESTION ID:3

Pairs of stereoisomers that are not mirror images of each other are called:

QUESTION ID:4

In 2014, scientists from Scripps Research Institute, California announced the development of 6 base DNA. A new base pair that they added to the standard 4 base (ATGC) DNA was called:

QUESTION ID:5

How much percentage of human genome is represented by the exome?

QUESTION ID:6

The most abundant monosaccharide in nature is:

QUESTION ID:7

From the evolutionary standpoint, extreme thermophiles are more closely connected with which one of the following:

QUESTION ID:8

Sulfur bacteria are examples of which of the following:

QUESTION ID:9

Which of the following has the highest heat of vaporization (J/g)?

QUESTION ID:10

QUESTION ID:11

From the following data, identify the correct pH value of sea water:

QUESTION ID:12

Hungry bone syndrome is associated with:

QUESTION ID:13

Match List-I with List-II:

QUESTION ID:14

In cytosol, the product yield from the oxidation of one molecule of glucose is:

QUESTION ID:15

Match List-I with List-II: 

QUESTION ID:16

An antigenic determinant to which a given antibody binds is called:

QUESTION ID:17

4-hydroxyproline is an example of:

QUESTION ID:18

A substance that can act either a base or an acid, is called:

QUESTION ID:19

A DNA or amino acid sequence consisting of the residues that most commonly occur at each position in a set of similar sequences are called:

QUESTION ID:20

A spatial arrangement of substituent groups that are free to assume different positions in space, without breaking any bonds (due to freedom in bond rotation) is called:

QUESTION ID:21

A series of overlapping clones defining an uninterrupted section of a genome, is called:

QUESTION ID:22

Enzymes that create a phosphodiester bond between the 3' end of one DNA segment and the 5' end of another, are called:

QUESTION ID:23

The component of the total energy of a system that can do work at constant temperature and pressure, is called:

QUESTION ID:24

The pH at which an amino acid has no net electric charge and thus does not move in an electric field, is called:

QUESTION ID:25

Enzymes that play two distinct roles, at least one of which is catalytic, the other may be catalytic, regulatory or structural, are called:

QUESTION ID:26

Which of the following statements are correct?

(A). DNA microarray is a collection of DNA sequences immobilized on a solid surface that can be probed by hybridization

(B). Differential centrifugation describes the separation of cell organelles by different rates of sedimentation

(C). Amino acids that cannot be synthesized by humans but are synthesized by microbes are called essential amino acids

(D). Equilibrium constant is specific for each chemical reaction

Choose the correct answer from the options given below:

QUESTION ID:27

Read the following statements carefully:

(A) DNA ligases are enzymes that create a phosophodiester bond between DNA fragments

(B). A protein containing one or more prosthetic groups is called a conjugated protein

(C). A type of enzyme inhibition reversed by increasing the substrate concentration is called competitive inhibition

(D). Two stereoisomers of a given sugar that differ only in the configuration about carbonyl carbon atom are called anomers

Choose the correct answer from the options given below.

QUESTION ID:28

A researcher engineers a lac operon on a plasmid inactivating all parts of the lac operator and the lac promoter, replacing them with the binding site for the LexA repressor and promoter regulated by LexA. The plasmid is introduced into E. coli cells that has a lac operon with an inactive lacZ gene. Under what conditions will these transformed cells produce β-galactosidase?

QUESTION ID:29

Which one of the following is the basis for protein structural classification?

QUESTION ID:30

The catabolic lysosomal degradation of cellular proteins is called:

QUESTION ID:31

Which one of the following i.e, no. of molecules per gram molecular weight, represents the Avogadro's number (N) ?

QUESTION ID:32

The energy derived from noncovalent interactions between enzyme and substrate is called:

QUESTION ID:33

One calorie (cal) equals to how many joules (J)?

QUESTION ID:34

Match List-I with List-II:

QUESTION ID:35

The number of enzyme units per miligram of total protein is called:

QUESTION ID:36

When a protein has two or more polypeptide subunits, their folding arrangement is called:

QUESTION ID:37

When wool sweaters are washed in hot water, they shrink. In contrast, when silk clothes are washed they do not shrink when washed under the same conditions.

(A). The β-woolen polypeptide chains are converted to the native α-helical conformation

(B). The structure of silk-β sheets is more stable than that of the wool

(C). The β-woolen polypeptide chains remain in their native conformation

(D). The structure of silk-β sheets is less stable than that of the wool protein structure

Choose the correct answer from the options given below:

QUESTION ID:38

A genetic mutation that limits the production of glucocerebrosidase, an enzyme that is responsible for breaking down fats, leads to which of the following disease:

QUESTION ID:39

Which one of the following is a disease caused by defect in the enzymes necessary for heme biosynthesis?

QUESTION ID:40

A mutation in the GLA (alpha galactosidase A) gene leads to which one of the following conditions?

QUESTION ID:41

A group of contiguous nucleotides codons in DNA molecule that does not include a termination codon is called:

QUESTION ID:42

The step in an enzymatic reaction of a pathway that needs greatest amount of activation energy is called:

QUESTION ID:43

A sequence in an mRNA that is required for binding bacterial ribsomes is called:

QUESTION ID:44

Hyponatremia is a condition where the concentration of the following ion decreases below normal level in plasma.

QUESTION ID:45

A human condition of acid-base disturbance with high H+ ions in the blood is called:

QUESTION ID:46

In kidneys the glomerular filtration rate (GFR) depends upon:

(A). the difference in hydrostatic and oncotic pressures between the glomerular capillaries and the lumen of the nephron

(B). the nature of glomerular basement membrane

(C). total available filtration area

(D). relative concentration of ions

Choose the correct answer from the options given below:

QUESTION ID:47

A decrease in the concentration of serum albumin lead to which of the following condition:

QUESTION ID:48

A patient presents herself with stunted growth, web like neck and an absence of X chromosome. What would be your diagnosis of this genetic condition?

QUESTION ID:49

Which of the following is the main cause of liver failure?

QUESTION ID:50

What is the rate of mortality in the acute liver failure?

QUESTION ID:51

In E.coli the enzyme that fills gaps in duplexes by stepwise addition of nucleotides to 3' end is called:

QUESTION ID:52

The enzyme reverse transcriptase:

QUESTION ID:53

Match List-I with List-II:

QUESTION ID:54

Another name for Vitamin D3 is:

QUESTION ID:55

Warfarin has which of the following functions?

QUESTION ID:56

Which of the following statements are correct?

(A). Some types of lipids play critical roles as cofactors or signals

(B). Prostaglandins are derived from arachidonate

(C). Steroid hormones are derived from sterols

(D). Vitamins D, A and E are fat soluble

Choose the correct answer from the options given below:

QUESTION ID:57

Phosphatidylcholine and phosphatidylserine are examples of:

QUESTION ID:58

Match List-I with List-II: 

QUESTION ID:59

Match List-I with List-II:  

QUESTION ID:60

Match List-I with List-II:   

QUESTION ID:61

In a substrate-enzyme reaction, the term K_a denotes which one of the following?

QUESTION ID:62

A metabolic condition in which the capacity of the body to buffer OH^- is diminished, is called:

QUESTION ID:63

Immune cells that ingest large particles and cells by phagocytosis are called:

QUESTION ID:64

Enzymes that are involved in the transfer of electrons (hydride ions or H atoms) are called:

QUESTION ID:65

Among following enzymes, which one has the highest turnover number (K_cat ?

QUESTION ID:66

Albinism is a genetic disorder associated with:

QUESTION ID:67

Of the following pH values which one is the lowest?

QUESTION ID:68

Among the following Liver Function Tests, which one indicates the hepatocellular damage?

QUESTION ID:69

The causes of increased Gamma-glutamyl Transferase (GGT) in human serum can be due to:

(A). Alcoholism

(B). Hepatitis

(C). Pancreatitis

(D). Liver metastasis

Choose the correct answer from the options given below:

QUESTION ID:70

Human acute liver failure can be due to:

(A). viral hepatitis

(B). medicine

(C) toxins

(D). ischemia

Choose the correct answer from the options given below:

QUESTION ID:71

Read the following statements carefully:

(A). ultracentrifugation separates molecules based on their density

(B). gel electrophoresis separates molecules based on their mobility in an electric field

(C). gel filtration separates molecules based on their size

(D). NMR separates molecules based on their proton signal

Choose the correct answer from the options given below:

QUESTION ID:72

One Angstrom (Å) is equal to :

QUESTION ID:73

In 1953, Frederick Sanger determined the amino acid sequence of which protein?

QUESTION ID:74

A substance that receives electrons in an oxidation-reduction reaction is called:

QUESTION ID:75

The substrate concentration at which an enzyme-catalyzed reaction proceeds at one-half of its velocity is called: