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QUESTION ID:1
Sickle-cell anemia is a disease characterised by the patient's erythrocyte, having a characteristic sickle or crescent shape. Select the correct statement about the disease -
QUESTION ID:2
Match List-I with List-II:
| List-I (Amino Acid) | List-II (pK value) |
| (A) α-Carboxyl groups | (I) 1.8-2.9 |
| (B) α-Amino groups | (II) 8.8-10.8 |
| (C) Acidic Amino Acid - Asp | (III) 12.5 |
| (D) Basic Amino Acid - Arg | (IV) 3.9 |
QUESTION ID:3
Gluconeogenesis synthesizes glucose from noncarbohydrate precursors.
(A) The main site of gluconeogenesis is the liver.
(B) Far lesser extent of gluconeogenesis occurs in kidneys.
(C) Very little gluconeogenesis occurs in brain or muscle.
(D) The second main site of gluconeogenesis is the heart.
Choose the correct answer from the options given below:
QUESTION ID:4
Match List-I with List-II:
| List-I (Organism) | List-II (Number of Chromosome) |
| (A) Fruit fly (Drosophila melanogaster) | (I) Diploid number 40 |
| (B) Nematode (Caenorhabditis elegans) | (II) Haploid number 06 |
| (C) Human (Homo sapiens) | (III) Haploid number 23 |
| (D) Mouse (Mus musculus) | (IV) Diploid number 08 |
QUESTION ID:5
People with hemophilia are unable to produce a factor needed for blood clotting; the cuts, bruises, and wounds of hemophiliacs continue to bleed and, if not stopped by transfusion with clotting factor, can cause death. Select the correct statement about hemophilia -
(A) The principal type of hemophilia in humans is due to a recessive X-linked mutation.
(B) These males have inherited the mutation from their heterozygous mothers.
(C) Affected males never transmit the mutant allele to their sons.
(D) Nearly all the individuals who have hemophilia are male.
Choose the correct answer from the options given below:
QUESTION ID:6
Clinical Syndrome : Karyotype : Chromosome Formula : Estimated Frequency at Birth
(A). Down Syndrome : 47, +13 : 2n+1 : 1/20,000
(B). Patau Syndrome : 47, +21 : 2n+1 : 1/2,000
(C). Edward Syndrome : 47, +18 : 2n+1 : 1/8000
(D). Klinefelter Syndrome : 47, XXY : 2n+1 : 1/500 male births
Choose the correct answer for the above statements from the options given below:
QUESTION ID:7
Match List-I with List-II:
| List-I (Enzyme) | List-II (Type of reaction catalyzed) |
| (A) Alcohol Dehydrogenase | (I) Bond formation coupled to ATP hydrolysis |
| (B) Trypsin | (II) Transfer of electrons |
| (C) Hexokinase | (III) Hydrolysis reactions |
| (D) Pyruvate carboxylase | (IV) Transfer of functional groups |
QUESTION ID:8
Match List-I with List-II:
| List-I (Coenzyme) | List-II (Precursor) |
| (A) Coenzyme A | (I) Vitamin B1 |
| (B) FAD, FMN | (II) Pantothenic Acid |
| (C) NAD+, NADP+ | (III) Vitamin B2 |
| (D) Thiamine pyrophosphate | (IV) Niacin |
QUESTION ID:9
Match List-I with List-II:
| List-I (Vitamin precursor) | List-II (Deficiency disease) |
| (A) Vitamin B1 | (I) Pernicious anemia |
| (B) Vitamin B2 | (II) Beriberi |
| (C) Vitamin B6 | (III) Growth retardation |
| (D) Vitamin B12 | (IV) Dermatitis |
QUESTION ID:10
Which of the following statements are correct regarding immunoglobulin A?
(A) IgA is the main class of antibody in secretions such as tears, saliva.
(B) IgA is also found in secretions of lungs and intestine.
(C) IgA is the first line of defense against infection at these sites.
(D) IgA is the main immunoglobin in the bloodstream late in the primary immune response.
Choose the correct answer from the options given below:
QUESTION ID:11
Match List-I with List-II:
| List-I (Pollutant) | List-II (Characteristics) |
| (A) Sulphur dioxide | (I) Colourless gas with an offensive 'rotten egg' odor, slightly water soluble |
| (B) Nitrogen dioxide | (II) Colourless, heavy, water soluble gas, with a pungent order. |
| (C) Ozone | (III) Reddish-brown gas, slightly water soluble. |
| (D) Hydrogen Sulfide | (IV) Pale-blue gas, water soluble, unstable, sweetish odor. |
QUESTION ID:12
Identify the rule that suggests that the endothermic animals from cold climates tend to have shorter extremities (ears and limbs) compared with animals from warmer climate-
QUESTION ID:13
Match List-I with List-II:
| List-I (Statistical Terminology) | List-II (Definition) |
| (A) Median | (I) The reciprocal of the average, of reciprocals, of the values, of items, of a series. |
| (B) Mean | (II) The value of the middle item, of series, when it is arranged in ascending or descending order of magnitude. |
| (C) Mode | (III) The value which we get by dividing the total, of the values of various given items in a series, by the total number of items. |
| (D) Harmonic mean | (IV) The most commonly or frequently occurring value in a series |
QUESTION ID:14
Calculate the harmonic mean of the numbers 4, 5, and 10 collected in one experiment.
QUESTION ID:15
Following are few statements with reference to Biostatistics. Choose the statement/s which are incorrect.
(A). Type II error : α-error
(B). Type I error : β-error
(C). Correct null hypothesis is rejected in β-error
(D). Wrong null hypothesis is accepted in α-error
Choose the correct option from the options given below:
QUESTION ID:16
After electrophoresis, the gel containing the seperated proteins, is immersed in an acid alcoholic solution, of the dye this -
(A) Denatures the proteins
(B) Fixes them in the gel
(C) Ensures they do not wash out
(D) Allows dye to bind them
Choose the correct answer from the options given below:
QUESTION ID:17
In the process of protein sequencing, trypsin and chymotrpsin are used for generating fragments. Select tryptic peptide from the list-
QUESTION ID:18
Which of the following statements related to transcription in bacteria/eukaryotes are correct?
(A) During concurrent promoter sequence recognition and melting, melting commences with base flipping, where two bases are flipped out into pockets of the primary sigma factor.
(B) Binding of α-amanitin to RNA polymerase II permits entry of nucleotides into RNA polymerase II active site and synthesis of RNA, but prevents translocation.
(C) RNA polymerase I cannot bind to upstream promoters.
(D) FACT is associated with RNA polymerase during transcriptional elongation and helps displace one histone octamer during transcription.
Choose the correct answer from the options given below:
QUESTION ID:19
Match List-I with List-II:
| List-I (Hormone) | List-II (Site of synthesis) |
| (A) Progesterone | (I) Adrenal cortex |
| (B) Testosterone | (II) Corpus luteum |
| (C) Estrone | (III) Testis |
| (D) Aldosterone | (IV) Ovary |
QUESTION ID:20
In the process of exploring eukaryote 80S ribosome, the following components may be observed -
(A) 28S rRNA, 5.8S rRNA
(B) 5S rRNA and 34 proteins
(C) 23S rRNA
(D) 5S rRNA and 49 proteins
Choose the correct answer from the options given below:
QUESTION ID:21
In an experiment, two fly populations are separately maintained, for many generations. Population A, contains closely related individuals, whereas, population B contains a set of unrelated individuals. Over many generations, it was observed that the fitness of individuals, in population A, is lower than the fitness of those in Population B, because -
QUESTION ID:22
Papain digestion of IgG antibody molecule results into -
QUESTION ID:23
Select the plant or ecosystem known to have highest energy conversion efficiency -
QUESTION ID:24
Select the vegetation type, having highest productivity, per unit weight (g leaf biomass-1 year-1) from the following sites –
QUESTION ID:25
Which one of the following are correct characteristic features set for bony fishes?
QUESTION ID:26
Match List-I with List-II:
| List-I (Hormone) | List-II (Function) |
| (A) Leptin | (I) Conversion of glycogen to glucose-1 phosphate |
| (B) Pancreatic polypeptide | (II) Suppresses appetite |
| (C) Parathyroid hormone | (III) Inhibits somatostatin secretion |
| (D) Epinephrine in skeletal muscle | (IV) Promotes formation of calcitriol |
QUESTION ID:27
Place these steps in temporal order, first to last:
(A) Exocytosis of synaptic vesicles.
(B) Binding of neurotransmitter molecules to its receptors.
(C) Opening of voltage-gated Ca2+ channels.
(D) Opening of Na+ channels and influx of sodium ions.
(E) Generation of post synaptic potential.
Choose the correct answer from the options given below:
QUESTION ID:28
Which of the following is NOT TRUE with respect to control of respiration?
QUESTION ID:29
The Asian mongoose and the American skunk, evolved independently of each other, but show similar structures and features, for e.g., ability to spray their attacker with musk. The similarities between the two organisms are most likely the result of -
QUESTION ID:30
Rifampicin, an inhibitor of RNA polymerase, is added to a bacterial culture. The culture is immediately divided into three fractions, to which radioactive thymine or uracil or methionine are added respectively. Five minutes later the cells are lysed and the radioactive label in all macromolecules is monitored. What will you observe?
QUESTION ID:31
N-linked glycosylation in proteins of eukaryotes is initiated in the -
QUESTION ID:32
Arrange the following in order of their action -
(A) G1 cyclin CDK Complex
(B) APC-cdh1
(C) S Phase cyclin CDK Complex
(D) APC-cdc20
Choose the correct SEQUENCE answer from the options given below:
QUESTION ID:33
Identify the correct statements related to sex linked inheritance in humans
(A) Males are considered to be hemizygous, for genes present on X-chromosome.
(B) Majority of sex-linked traits are carried on the X-chromosome.
(C) Genes that are not sex-linked are present in somatic cells and absent in germ cells.
(D) 1:1 ratio of males and females in humans, is the result of meiosis in males.
(E) The single X-chromosome, present in the father, is inherited by the son.
Choose the correct answer from the options given below:
QUESTION ID:34
Match List-I with List-II:
| List-I (Structure) | List-II (Details relating to structure) |
| (A) Diaphysis | (I) The regions between the diaphysis and epiphysis |
| (B) Epiphysis | (II) A thin membrane that lines the internal bone surface |
| (C) Metaphysis | (III) The proximal and distal end of the bone |
| (D) Endosteum | (IV) The long cylindrical main portion of the bone |
QUESTION ID:35
Match List-I with List-II:
| List-I (Species) | List-II (Identifying Characters of species) |
| (A) Allopatric Species | (I) Species inhabiting the same geographical area |
| (B) Sympatric Species | (II) Species inhabiting different geographical areas |
| (C) Sibling Species | (III) Species occupying separate areas, that share a common boundary |
| (D) Parapatric Species | (IV) Species which are morphologically identical, but reproductively isolated. |
Choose the correct answer from the options given below:
QUESTION ID:36
Arrange the events in correct order of sequence
(A) Cleavage
(B) Cortical rotation
(C) Mid-blastula transition
(D) Gastrulation
Choose the correct SEQUENCE answer from the options given below:
QUESTION ID:37
Arrange the following in the correct sequence of DNA packaging -
(A) DNA scaffold
(B) Nucleosome formation
(C) Chromatosome formation
(D) Histone dimerization
Choose the correct answer from the options given below:
QUESTION ID:38
Arrange the following animals on the basis of their phyla, according to increasing level of complexity -
(A) Scolopendra
(B) Nereis
(C) Dentalium
(D) Euplectella
(E) Physalia
Choose the correct answer from the options given below:
QUESTION ID:39
Arrange the following evolutionary events in the history of horse evolution chronologically -
(A) Miohippus
(B) Orohippus
(C) Hyracotherium
(D) Merychippus
Choose the correct answer from the options given below:
QUESTION ID:40
Which of the following statements are true?
(A) Differential gene expression can occur only at the level of transcription
(B) RNA polymerase binds to the promoter region to initiate transcription
(C) Enhancers regulate transcription
(D) Transcription factors can recognize specific sequences of DNA in heterochromatic region
Choose the correct answer from the options given below:
QUESTION ID:41
Which two embryological structures together form the bilaminar disc?
QUESTION ID:42
Cytoskeleton of eukaryotic cells consists of
(A) Peptidoglycans
(B) Microtubules
(C) Chitin
(D) Microfilaments
(E) Cellulose
Choose the correct answer from the options given below:
QUESTION ID:43
Which of the following statements is true concerning infrared spectroscopy?
QUESTION ID:44
Match List-I with List-II:
| List-I (Phase) | List-II (Characteristics of the phase) |
| (A) Lag Phase | (I) Dying cells are higher than the dividing cells. |
| (B) Log Phase | (II) Number of new cells equal to dying cells. |
| (C) Stationary Phase | (III) Adoption to the nutrient environment. |
| (D) Decline Phase | (IV) Binary fission is at maximum rate. |
QUESTION ID:45
Match List-I with List-II:
| List-I (Technique) | List-II (Connecting/purpose) |
| (A) DNA footprinting | (I) Protein-protein interaction |
| (B) Yeast two hybrid system | (II) VNTR |
| (C) DNA fingerprinting | (III) DNA binding protein |
| (D) SAGE | (IV) Transcriptome analysis |
QUESTION ID:46
Match List-I with List-II:
| List-I (Structure) | List-II (Function) |
| (A) Ascending loop of Henle | (I) Reabsorption of glucose |
| (B) Descending loop of Henle | (II) Sodium is actively thrown out |
| (C) Proximal tubule | (III) Diffusion of water |
| (D) Collecting duct | (IV) Passive entry of sodium |
QUESTION ID:47
Sequentially arrange the following steps involved in blood clot formation -
(A) Conversion of fibrinogen to fibrin
(B) Conversion of prothrombin to thrombin
(C) Adhesion and aggregation of platelets on damaged vessels
(D) Prothrombinase formed by extrinsic or intrinsic pathway
(E) Reduction of blood loss by initiation of a vascular system
Choose the correct answer from the options given below:
QUESTION ID:48
Estrous and menstrual cycle are two types of cycles, that occur in female mammals. Both cycles begin after sexual maturity in females. Reproductive hormones induce these cycles in females. These cycles happen in order to prepare female mammals, for holding a child during pregnancy.
The primary difference between estrous and menstrual cycles is -
QUESTION ID:49
Which of the following statements about cortisol are correct?
(A) It decreases the circulating lymphocytes
(B) It increases the circulating eosinophils.
(C) It decreases the production of prostaglandins
(D) It inhibits the production of fibroblasts
(E) It alters immune system responses and suppresses the digestive and the reproductive systems.
Choose the correct answer from the options given below.
QUESTION ID:50
Which of the following statements made with regards to plasmid incompatibility are true?
(A) Plasmids having the same origin of replication, belong to the same incompatibility group.
(B) Plasmids having different origins of replication, belong to the same incompatibility group
(C) Plasmids of the same incompatibility group are compatible.
(D) Plasmids of the same incompatibility group are incompatible.
Choose the correct answer from the options given below:
QUESTION ID:51
Which organism's species have greater diversity in the Western Ghats than the Eastern Ghats?
QUESTION ID:52
Which of the following is a feature of a stable community?
QUESTION ID:53
The transition zone in biosphere reserve -
QUESTION ID:54
Migratory species pose special preservation challenges, because
QUESTION ID:55
Which of the following protected areas are declared Tiger Reserves in India?
(A) Bandipur
(B) Bhitarkanika
(C) Manas
(D) Sunderbans
(E) Kaziranga
Choose the correct answer from the options given below:
QUESTION ID:56
Which of the following disease in humans, is caused due to expanded microsatellite repeats?
QUESTION ID:57
Microorganisms that produce antibiotics are unaffected by the same antibiotic. One of the mechanism to explain this is -
QUESTION ID:58
A student was asked to clone a DNA fragment, flanked by BamHI (GGATCC) sites into a vector, cut with Bglll (AGATCT). The cloning was successful, as these two restriction enzymes are known to create compatible sites. Based on this, what will be the restriction site configurations of these two enzymes (indicates the point of enzymatic cleavage).
QUESTION ID:59
During gastrulation in Xenopus frog, the blastocoel
QUESTION ID:60
Following statements are with reference to oogonia. Which of these is incorrect?
QUESTION ID:61
The following is the list of steps, involved in the transfer of bacterial DNA by generalized transduction. Which option represents the correct sequence of steps?
(A) Packaging of host genomic DNA fragment, into P1 phage head.
(B) Injection of DNA of transducing particle, into bacterial host
(C) Injection of P1 phage DNA, into bacterial host.
(D) Release of transducing particle, into bacterial host.
(E) Fragmentation of host genomic DNA, by phage-encoded endonuclease.
Choose the correct answer from the options given below:
QUESTION ID:62
The following is the list of steps involved in cloning of a gene. Which option represents the correct sequence of the process?
(A) Transformation with blue and white selection.
(B) RFLP analysis.
(C) Isolation of plasmid DNA.
(D) Ligation of gene, into TA-cloning vector.
(E) Amplification of gene by PCR, using Taq DNA polymerase.
Choose the correct answer from the options given below:
QUESTION ID:63
Match List-I with List-II:
| List-I (Mammalian order) | List-II (Examples) |
| (A) Perissodactyla | (I) Porcupines |
| (B) Primates | (II) Flying lemurs |
| (C) Dermoptera | (III) Rhinoceroses |
| (D) Rodentia | (IV) Horse |
QUESTION ID:64
Match List-I with List-II:
| List-I (Taxonomic Unit) | List-II (Representative Example) |
| (A) Brachiopods | (I) Proboscis worms |
| (B) Ctenophores | (II) Lamp shells |
| (C) Nemertea | (III) Comb jellies |
| (D) Onychophorans | (IV) Velvet worms |
QUESTION ID:65
Which of the following statements are INCORRECT?
(A) Many animals with protostome development undergo spiral cleavage.
(B) Flat worms exhibit radial symmetry.
(C) Ray-finned fishes are also called sarcopterygians.
(D) Lophophore is a crown of ciliated tentacles that function in feeding.
Choose the correct answer from the options given below:
QUESTION ID:66
Bacteria produce an enzyme methylase which plays role in:
QUESTION ID:67
Dung beetles live in regions where cattle graze, quickly burying and recycling cattle droppings. Because of the dung beetles' activities, breeding habitats for disease-carrying flies are reduced, and the plants upon which cattle feed are nourished. The relationship between the dung beetles and disease-carrying flies is a type of:
QUESTION ID:68
Being a medical science student, in your very first anatomical investigation of a female body, arrange the order of appearance of following organs of immunological importance, in anterior to posterior direction in the body.
(A) Thymus
(B) Adenoids
(C) Peyer's patches
(D) Spleen
Choose the correct answer from the options given below:
QUESTION ID:69
Which of the following molecules is NOT found in the Eosinophilic granule?
QUESTION ID:70
The correlation between the observed and predicted values of the outcome variable is known as:
QUESTION ID:71
The square root of the variance is known as:
QUESTION ID:72
A protein coding gene in the mouse was mutated such that the resultant protein was non-functional. The phenotypic effect of the mutation was observed in homozygous mutant mice, in heterozygous mice that inherited the mutation from the mother, and in heterozygous mice that inherited the mutation from the father.
This suggests that:
QUESTION ID:73
In a sucrose density gradient, what is the order of organelle sedimentation from lower to higher concentration of sucrose?
QUESTION ID:74
Select the correct statement about the membrane transport:
(A) Channel proteins form open pores through which small-sized molecules/ions can cross the membrane.
(B) Carrier proteins selectively bind specific molecules, and transport them across the membrane by undergoing a conformational change.
(C) Transport of molecules across membranes, through channel proteins and carrier proteins, always involves active transport.
(D) Small uncharged molecules can diffuse freely through the phospholipid layers.
Choose the correct answer from the options given below:
QUESTION ID:75
Capacitation is a process in which the:
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