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QUESTION ID:1
Match List-I with List-II
| List-I | List-II |
| (Receptor) | (Ligand) |
| (A). GPCR | (I). Triiodothyronine |
| (B). TxR | (II). Erythropoetin |
| (C). RTK | (III). Vasopressin |
| (D). NRTK | (IV). IGF 1 |
QUESTION ID:2
Match List-I with List-II
| List-I | List-II |
| (Disease/ Disorder) | (Clinical parameter) |
| (A). Kidney failure | (I). Hypoalbuminemia |
| (B). Liver Cirrhosis | (II). Increase in creatine kinase |
| (C). Myocardial infarction | (III). Increase in BUN |
| (D). Skeletal muscle disorders | (IV). Increase in SGPT |
QUESTION ID:3
Match List-I with List-II
| List-I | List-II |
| (Types of Hypersensitivity) | (Immune mechanism involved) |
| (A). Type I | (I). IgG mediated |
| (B). Type II | (II). T-cell mediated |
| (C). Type III | (III). IgE mediated |
| (D). Type IV | (IV). Immune complex mediated |
QUESTION ID:4
The site on an antigen that binds to an antibody is known as
QUESTION ID:5
Which of the following is NOT a part of the healthy gut microbiome?
QUESTION ID:6
Which one of the following physiological processes is NOT regulated by hypoxia-induced HIF?
QUESTION ID:7
Which of the following is contraindicated for a person with phenylketonuria?
QUESTION ID:8
Which one of the following biomolecule is not present in plasma?
QUESTION ID:9
Arrange the following events in the correct sequence of their occurrence during starvation/fasting:
(A) Activation of adenylate cyclase
(B) Activation of CREB
(C) Activation of secretion by alpha cells
(D) Activation of PKA
(E) Synthesis of PEPCK
Choose the correct answer from the options given below:
QUESTION ID:10
Which one of the following bonds is NOT a covalent bond?
QUESTION ID:11
Match List-I with List-II
List-I (Solute transport) | List-II (Type of membrane transport) |
| (A). Release of carbon dioxide into the blood plasma | (I). Primary active transport |
| (B). Glucose uptake by the intestinal epithelial cells | (II). Facilitated diffusion |
| (C). Calcium uptake by sarcoplasmic endoplasmic reticulum for storage | (III). Simple diffusion |
| (D). Glucose uptake by erythrocytes | (IV). Secondary active transport |
QUESTION ID:12
Which of the following is NOT a tumor suppressor gene product?
QUESTION ID:13
At which stage of the cell cycle, the dividing cell is arrested by colchicine treatment?
QUESTION ID:14
A chromatography was performed to separate four proteins (A, B, C, D) by anion exchange chromatography using a buffer with pH 7.5. The isoelectric points of the proteins A, B, C, D are 6.5, 7.0, 5.5, and 8.0, respectively. The proteins were eluted using a salt gradient. Arrange the order (from first to last) in which the four proteins will be eluted:
QUESTION ID:15
Match List-I with List-II
List-I (Regulatory protein) | List-II (Function during the cell cycle) |
| (A). CKI | (I). Cell cycle arrest in response to DNA damage |
| (B). APC/C | (II). Binds to E2F and prevent the transcription of S-phase genes |
| (C). p53 | (III). Separation of sister chromatids during anaphase |
| (D). Rb protein | (IV). Inhibits the activity of cyclin dependent kinases |
QUESTION ID:16
Where will a secretory protein be transported from the Golgi complex, if its KDEL signal sequence is mutated to KEEL?
QUESTION ID:17
Dinitrophenol affects oxidative phosphorylation and ATP biosynthesis because:
QUESTION ID:18
Match List-I with List-II
List-I (Regulatory enzyme) | List-II (Metabolic pathway) |
| (A). Phosphoenolpyruvate carboxykinase | (I). Urea cycle |
| (B). Carbamoyl phosphate synthase II | (II). Fatty acid biosynthesis |
| (C). Phosphofructokinase-1 | (III). Gluconeogenesis |
| (D). Acetyl-CoA carboxylase | (IV). Glycolysis |
QUESTION ID:19
Lipid rafts are rich in which of the following components?
QUESTION ID:20
How many centrioles are present in a cell that is at the prophase stage of the mitosis?
QUESTION ID:21
Match List-I with List-II
List-I (Biochemical technique) | List-II (Application) |
| (A). Ion exchange chromatography | (I). Isolation of mitochondria from a cell extract |
| (B). Centrifugation | (II). Separation of a mixture of proteins |
| (C). ELISA | (III). Separation of genomic DNA |
| (D). Agarose gel electrophoresis | (IV). Detection of viral antigen in blood samples |
QUESTION ID:22
Match List-I with List-II
List-I (Biomolecule) | List-II (Cellular function) |
| (A). Enzyme | (I). Cellular catalysis |
| (B). Cholesterol | (II). Cellular communication |
| (C). Glycolipid | (III). Membrane fluidity |
| (D). Glycoprotein | (IV). Recognition of the cell |
QUESTION ID:23
SDS-PAGE is NOT used for:
QUESTION ID:24
Which of the following statements are FALSE with reference to properties of hemoglobin and myoglobin?
(A). Heme is the prosthetic group, not present in both
(B). Both have same oxygen binding capacity
(C). Hemoglobin is an Fe containing tetramer with high oxygen binding capacity
(D). Myoglobin is a Mg containing monomer with high oxygen binding capacity
(E). Hemoglobin is a heterotetramer while myoglobin is a monomer
Choose the correct answer from the options given below:
QUESTION ID:25
Arrange the following steps involved in the activation of steroid receptor TxR by thyroxine in the correct order:
(A). Increase in BMR
(B). Binding to hormone response element (HRE)
(C). Dimerization and localization into the nucleus
(D). Binding of ligand to receptor
(E). Transcriptional regulation
Choose the correct answer from the options given below:
QUESTION ID:26
Positive nitrogen balance occurs in which one of the following conditions?
QUESTION ID:27
Familial hypercholesterolemia occurs due to mutation in:
QUESTION ID:28
Which of the following are the normal constituents of human urine?
(A). Urea
(B). Creatinine
(C). Ammonia
(D). Alanine
(E). Uric Acid
Choose the correct answer from the options given below:
QUESTION ID:29
Who is known as the Father of microbiology?
QUESTION ID:30
During mating between Hfr strain and F- recipient cell:
QUESTION ID:31
Match List-I with List-II
List-I (Micronutrient deficiency) | List-II (Symptoms) |
| (A). Copper | (I). Megaloblastic anemia |
| (B). Folate | (II). Normocytic hypochromic anemia |
| (C). Vitamin C | (III). Microcytic hypochromic anemia |
| (D). Iron | (IV). Bleeding gums |
QUESTION ID:32
Chargaff rule states:
QUESTION ID:33
CpG island in the human genome is related to:
QUESTION ID:34
Which of the following cannot be converted to glucose in animals?
QUESTION ID:35
Match List-I with List-II
List-I (Enzyme) | List-II (Function in DNA replication) |
| (A). Topoisomerase | (I). ATP driven unwinding of DNA |
| (B). DNA primase | (II). Seals the Okazaki fragments of lagging strand |
| (C). Helicase | (III). Relieves torsional strain during unwinding of DNA |
| (D). DNA Ligase | (IV). Initiates synthesis of RNA primers |
QUESTION ID:36
Which of the following lipids is not present in the cell membrane?
QUESTION ID:37
Water is a universal solvent due to the following properties:
(A). Ability to form H-bonds
(B). High dielectric constant
(C). Low polarity
(D). Low specific heat
Choose the correct answer from the options given below:
QUESTION ID:38
Arrange the following steps of formation of an atherosclerotic plaque in the order in which they occur.
(A). Infiltration of foam cells
(B). Formation of fatty streaks
(C). Injury to blood vessels
(D). Formation of calcified streak
(E). Formation of thrombus
Choose the correct answer from the options given below:
QUESTION ID:39
Albumin deficiency in blood may lead to:
QUESTION ID:40
Which of the following statements are true about the mechanism of action of CAP in lac operon?
(A). CAP is a positive regulator of lac operon.
(B). When glucose is absent and lactose is present, CAP is inactive due to high levels of cAMP.
(C). When glucose and lactose are present, CAP is inactive.
(D). When glucose is present and lactose is absent, CAP is inactive due to low levels of cAMP.
Choose the correct answer from the options given below:
QUESTION ID:41
Which of the following has the maximum standard free energy of hydrolysis?
QUESTION ID:42
When Luciferin yellow, a dye dissolved in buffer, is injected into a neuron of the retina, neighbouring neurons get labeled. If the retina is incubated with dopamine prior to injection of the dye, only the injected neuron is labeled. Because:
(A). Neurons communicate through gap junctions
(B). Dopamine moves through gap junctions
(C). Dopamine decreases gap junction permeability
(D). Dopamine inhibits synaptic transmission
(E). Luciferin yellow is hydrophobic and can move between cells
Choose the correct answer from the options given below:
QUESTION ID:43
Which of the following are anaplerotic enzymes?
(A). Glutamine deaminase
(B). Aspartate transaminase
(C). Alanine transaminase
(D). Glucose-6-phosphate dehydrogenase
(E). Pyruvate carboxylase
Choose the correct answer from the options given below:
QUESTION ID:44
Which of the following enzyme catalyzes the substrate level phosphorylation?
QUESTION ID:45
In an enzyme catalyzed reaction, what fraction of Vmax would be obtained when S = 1/2 Km?
QUESTION ID:46
In a competitive ELISA, the color intensity is:
QUESTION ID:47
Arrange the following steps of T-cell response in the order in which they occur.
(A). Activation of Tc cells
(B). Destruction of the host cell
(C). Processing and presentation in association of MHC class I
(D). Formation of CTL and target cell synapse
Choose the correct answer from the options given below:
QUESTION ID:48
Which of the following transmits antibiotic resistance in bacteria?
QUESTION ID:49
Arrange the steps for conversion of DHAP to acetyl CoA in the order in which they occur.
(A). Formation of PEP
(B). Movement to mitochondria
(C). Action of Pyruvate kinase
(D). Activity of PDH
(E). Formation of 1, 3 bisphosphoglycerate
Choose the correct answer from the options given below:
QUESTION ID:50
A child has no detectable T-lymphocytes and B-lymphocytes. The defect is likely to be in:
QUESTION ID:51
Myasthenia gravis is an autoimmune disorder caused by which of the following?
QUESTION ID:52
Arrange the following steps involved in a polymerase chain reaction in the correct sequence of their occurrence.
(A). Annealing of primers with template DNA
(B). Denaturation of template DNA
(C). Analysis of the PCR product on agarose gel electrophoresis
(D). Extension of strand by polymerase
Choose the correct answer from the options given below:
QUESTION ID:53
For an enzyme catalyzed reaction, which of the following statements will be correct?
(A). Enzyme lowers the activation energy
(B). Enzyme changes the reaction equilibrium
(C). Enzyme does not affect the activation energy
(D). Enzyme increases the rate of the reaction
(E). Enzyme doesn't affect the reaction equilibrium
Choose the correct answer from the options given below:
QUESTION ID:54
Which of the following events will be observed in a plasma cell undergoing a molecular rearrangement for class switching to IgA?
(A) DNA sequence containing V, D and J gene segments translocated near the Cα DNA exon
(B) mRNA specific for μ chain
(C) mRNA specific for λ and κ chains
(D) mRNA specific for β chain of TCR
(E) mRNA specific for α chain
Choose the correct answer from the options given below:
QUESTION ID:55
Genome of virus is composed of single stranded DNA molecule which is 109 bases long. How many moles of genomic DNA is present in bacteria?
QUESTION ID:56
Which conformation of glucose is the most stable?
QUESTION ID:57
What is the order of sedimentation of various subcellular organelles in the differential centrifugation method?
(A). Mitochondria
(B). Microsomes
(C). Nucleus
(D). Peroxisomes
Choose the correct answer from the options given below:
QUESTION ID:58
IgM is a pentamer. Upon visualization of pure IgM sample on SDS-PAGE, the number of bands seen on the gel will be:
QUESTION ID:59
The wavelength of light used for measuring absorbance of protein samples by spectrophotometry is:
QUESTION ID:60
Amylose is a polymer of
QUESTION ID:61
Which DNA has a left-handed double helix?
QUESTION ID:62
Which of the following amino acids has the maximum and minimum number of allowed conformations in the Ramachandran plot, respectively?
QUESTION ID:63
Arrange the levels of DNA packaging observed in the eukaryotic genome in a hierarchical order.
(A). Chromosome
(B). Nucleosome
(C). Chromatin
(D). Solenoid
(E). 10nm chromatin fibril
Choose the correct answer from the options given below:
QUESTION ID:64
Fatty acylated form of sphingosine is called:
QUESTION ID:65
If 6.5 grams of protein was fully oxidized in a human, what would be the net energy released?
QUESTION ID:66
Which of the following will have the highest glycemic index?
QUESTION ID:67
A strict vegan person will show deficiency symptoms of:
QUESTION ID:68
What is the ultimate electron acceptor in the electron transport chain of photophosphorylation?
QUESTION ID:69
How many fragments will be produced when the following peptide is digested with the chymotrypsin?
G-S-F-P-L-T-L-Y-S-W-S-S
QUESTION ID:70
Which of the following enzyme is used in the food industry for meat tendering process?
QUESTION ID:71
Which of the following is the inhibitor of protein synthesis in a cell?
QUESTION ID:72
Competitive inhibition of an enzyme can be overcome by:
QUESTION ID:73
To study the lateral diffusion rate of the membrane phospholipids, FRAP (Fluorescence recovery after photobleaching) was performed on a sample membrane under different experimental conditions. To study the effect of temperature, the temperature of the sample tube was gradually lowered from 37°C to 10°C. Which of the following statements are incorrect?
(A) Rate of phospholipid diffusion will be highest at 10°C
(B) Rate of phospholipid diffusion will be highest at 37°C
(C) Rate of phospholipid diffusion will be lowest at 10°C
(D) Rate of phospholipid diffusion will be lowest at 37°C
(E) Rate of phospholipid diffusion remains constant at all temperatures
Choose the correct answer from the options given below:
QUESTION ID:74
Which class of enzymes hydrolyze the ATP molecule into ADP and Pi to generate energy for covalent bond formation?
QUESTION ID:75
Arrange the following molecules in order of their ability for transmembrane diffusion through a lipid bilayer (from the highest to the lowest diffusion rate).
(A). Glucose
(B). Calcium ion
(C). Carbon dioxide
(D). RNA
(E). Water
Choose the correct answer from the options given below:
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