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Previous Year Questions

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TLS Online TPP Program

QUESTION ID:1

Degradation by lysosomes involves

QUESTION ID:2

Protein misfolding is NOT prevented by 

QUESTION ID:3

Which of the following statements regarding the proteolytic action of trypsin is correct? 

QUESTION ID:4

The cells of Triticum aestivum and Rana tigrina differ in the presence or absence of

QUESTION ID:5

Which of the following is responsible for the transport of ground water from roots to the apex of a 40-feet high Eucalyptus trees? (DROP)

QUESTION ID:6

Which of the following is NOT a stop codon?

QUESTION ID:7

Which of the following amino acids contains a Sulphur atom? 

QUESTION ID:8

Which of the following polysaccharides has the maximum number of branches? 

QUESTION ID:9

Which of the following is the least reactive functional group

QUESTION ID:10

Which of the following biomolecules contains cobalt?

QUESTION ID:11

How many structural isomers are possible for a chemical compound of the molecular formula C3H7Cl?

QUESTION ID:12

Which of the following is NOT a property of phenols?

QUESTION ID:13

Absorbance (A) as measured by a spectrophotometer is defined by the following equation


where, (I0) is the intensity of the incident light, and (I) is the intensity of the transmitted light. For a sample that absorbs at a particular wavelength, why is the absorbance at that wavelength a positive number?

QUESTION ID:14

Match List I with List II

List IList II
Metal/Non-metalPhysical property
A. IodineI. Metal, which is poor conductor of heat
B. MercuryII. Very soft metal, which can be cut with a knife
C. LeadIII. Non-metal, which has lusture
D. PotassiumIV. Metal, liquid at room temperature
Choose the correct answer from the options given below: 

QUESTION ID:15

NH3 molecules have ________________ geometry and ________________ shape.

QUESTION ID:16

How much volume of 1 M NaOH solution should be taken to prepare 1000 mL of 0.2 M NaOH solution? 

QUESTION ID:17

Three wheels can complete 40, 24 and 15 revolution per minute, respectively. There is a red spot on each wheel that touches the ground at time zero. After how much time, all these spots will simultaneously touch the ground again?

QUESTION ID:18

A wheel makes 2000 revolutions in covering a distance of 88 km. The radius of the wheel is

QUESTION ID:19

Mohan spends 20% of his monthly income on education of his children, 50% of the remaining income on food and 50% of the still remaining income on house rent and transport. If he now has Rs. 2,000 left with him, what is his monthly income?

QUESTION ID:20

A fixed number of workers were originally assigned to complete a piece of work in 32 days. But 10 workers remained absent throughout, so the work was completed in 40 days. How many workers were originally assigned the work?

QUESTION ID:21

The present ratio of the ages of two girls is 4 : 5. After 2 years, the ratio will become 6 :7. The ratio of their ages after 10 years will be

QUESTION ID:22

If cotA =  and cosecB = 2. The value of A + B will be

QUESTION ID:23

A train is moving at an average speed of 200/9 m/sec. It covers a distance of 1760 km in one day (24 h). It has stoppage during its 24 h journey at 6 stations for the same period of time. What is the time for which it stops at each station? 

QUESTION ID:24

In the give figure, POQ is a straight line. What is the value of x?

QUESTION ID:25

Average monthly salary of the total 800 workers in a factory is Rs. 600. Average monthly salary of officers of the factory is Rs. 2,500, but average monthly salary of other workers is Rs. 500. Find the number of workers in the factory?

QUESTION ID:26

Find the missing number (?) in the series shown in the diagram starting from 6 in clockwise manner. 


QUESTION ID:27

If "ALONG is coded as "DIRKJ' and 'BELOW' is coded as 'EBOLZ', then consider the following two statements.

Statement I : 'ABOVE' will be coded as 'DYRSH'.
Statement II : 'ASIDE' will be coded as 'DUFGH'.

In the light of above statements, choose the correct answer from the options given below :

QUESTION ID:28

Thirty-six vehicles are parked in a parking lot in a single row. After the first car, there is one scooter. After the second car, there are two scooters and after the third car three scooters and so on. How many scooters are there in the second half of the row?

QUESTION ID:29

Two students went to a shop. First student bought two pens and five pencils. Second student bought three pens and three pencils. They both paid the same amount of Rs. 18. If the prices of the pen and pencil were whole number, what is the price of one pencil in rupees?

QUESTION ID:30

There are 50 students in a class. Some students are studying only English, while some are studying only Hindi. 15 students are studying both languages. If the total number of students who are studying English are 22, then, how many students are studying only Hindi and only English?

QUESTION ID:31

Two cars, A and B, start from the opposite points of a road, which is 200 km long. Car A runs for 30 km and takes a right turn and then runs for 20 km and then turns left and runs for 35 km. It again first turns left and then right to reach at a point on the same road. In the meantime, due to minor breakdown, car B has run only 30 km along the road and stopped. What would be the distance between the two cars at this point, when car A again enters the road?

QUESTION ID:32

If circle is to circumference, then square is to

QUESTION ID:33

Give below are two statements : one is labelled as Assertion A and other is labelled as Reason R.
Assertion A : An electric bulb makes a 'bang' when it is broken.
Reason R : The air inside the bulb rushes out immediately on breaking.
In the light of the above statements, choose the most appropriate answer from the options given below

QUESTION ID:34

Student 'A' and student 'B' are ranked 10th and 15th positions, respectively, from the top in a class of 50 students. What will be their respective ranks from the bottom in the class?

QUESTION ID:35

If seventh day of a month is three days earlier than Friday, what day will be on the nineteenth day of the month?

QUESTION ID:36

Five boys, A, B, C, D and E, participated in a race. B finished the race before C, but after A. A finished race before E and D. D finished the race after C, but before E. Who finished the race at the third place?

QUESTION ID:37

Out of the four words given below, three are alike in some manner. Choose the odd one out.

QUESTION ID:38

Arrange the following words in a meaningful sequence.
A. Chair
B. Furniture
C. Forest
D. Wood
E. Trees
Identify which of the following sequence is most appropriate in this regard?

QUESTION ID:39

Anita, Ram’s daughter, says to Mala that your mother Neeta is the younger sister of my father, who is the third child of Sohan. What is Sohan’s relation with Mala?

QUESTION ID:40

Find the missing term (?) in the alpha numeric series, M3R, J6T, ? , D15X, A21Z.

QUESTION ID:41

Find the next number (?) in the series, 6, 13, 25, 51, 101, ?

QUESTION ID:42

Watt is related to 'Power' in the same way as 'Pascal' is related to

QUESTION ID:43

You are given a statement followed by two assumptions, numbered I and II. You have to consider the statement and the assumptions and decide which assumptions is implicit in the statement.

Statement : If he works hard, he will pass the examination.
Assumption I : To pass he must work hard.
II : He will pass the examination.

QUESTION ID:44

In the given diagram, three categories of population are represented. The triangle represents doctors, the square represents married persons, and the circle represent the person living in nuclear families.

Married person living in nuclear families, but not working as doctor are represented by

QUESTION ID:45

What will be the next image in the following sequence?


QUESTION ID:46

Find then missing number (?) by starting from the top number moving in the clockwise direction.


QUESTION ID:47

Which of the following position of a box can be seen when the given sheet in fig(x) is folded to form a box?


Choose the correct answer from the options given below.

QUESTION ID:48

Match List I with  List II.

List IList II
WordWater image
A. STOPI. bOƧ⊥
B. POTSII. ⊥ObƧ
C. POSTIII. Ƨ⊥Ob
D. TOPSIV. bO⊥Ƨ
Choose the correct answer from the options given below : 

QUESTION ID:49

Who is the heaviest among A, B, C, D and E, if C is heavier than B and E but lighter than D, and D is not the heaviest? 

QUESTION ID:50

If 1st March of a year is Monday, then which day will it be on the same date of the following year, given that the following year is a leap year?

QUESTION ID:51

Which of the following organisms is used in production of citric acid at industrial scale? 

QUESTION ID:52

Arrange the following in the decreasing energy content (kCal/g)
A. Petrol
B. Ethanol
C. Butanol
D. Hydrogen

Choose the correct answer from the options given below :

QUESTION ID:53

Which of the following statement are correct for RuBisCO?
A. It is found only in green plants and algae.
B. It is a bifunctional enzyme.
C. It catalyzes the binding of CO2 to 3-phosphoglycerate.
D. It is involved in electron transport in plants.
E. It catalyzes the binding of CO₂ to rubulose-1, 5-bisphosphate.

Choose the correct answer from the options given below :

QUESTION ID:54

An increase in pH of the broth during yeast fermentation can be due to
A. catabolite repression.
B. use of amino acids as the carbon source.
C. excess glucose concentration in the medium.
D. reduced oxygen levels.
E. low residual glucose in the medium.

Choose the correct answer from the options given below :

QUESTION ID:55

Which of the following is NOT a product of anaerobic metabolism?

QUESTION ID:56

Amongst the potatoes purchased by you, one looks green. Which of the following is true for the green potato? 

QUESTION ID:57

When metaphase chromosomes are briefly subjected to mild heat or proteolysis, G bands are detectable by

QUESTION ID:58

Which of the following statements is NOT true for transposable elements?

QUESTION ID:59

The chloride-bicarbonate exchanger of the erythrocyte membrane is a/an

QUESTION ID:60

In comparison to covalent bonds, hydrogen bonds are

QUESTION ID:61

What is the role of sigma factor in prokaryotic transcription?

QUESTION ID:62

Cells expressing fluorescent proteins can be isolated by

QUESTION ID:63

The genetically inheritable information is stored in

QUESTION ID:64

Which among the following is NOT an organelle?

QUESTION ID:65

Which among the following is NOT known to be a second messenger?

QUESTION ID:66

Controlled trials, demonstrating efficacy of a drug or a device necessary for federal regulatory approval, are termed as

QUESTION ID:67

The ability to taste the compound phenylthiocarbamide (PTC) is controlled by a dominant allele 'T'. Individuals homozygous for the recessive allele 't' are unable to taste PTC. In a class of 100 students, 84 can taste PTC and rest cannot. If the population follows Hardy-Weinberg law, the frequency of the heterozygotes in the population would be

QUESTION ID:68

Anaphase promoting complex, or cyclosome (APC/C) catalyzes the ubiquitylation and destruction of 'securin' that leads to the

QUESTION ID:69

Which of the following is the most abundant biomolecule on planet earth?

QUESTION ID:70

Which of the following is NOT correct about the Circular dichroism spectroscopy?

QUESTION ID:71

β-oxidation of fatty acids takes place in 

QUESTION ID:72

Okazaki fragments are formed during

QUESTION ID:73

Which of the following amino acids generally destabilize α-helices in proteins?

QUESTION ID:74

A student is purifying an unknown protein from a newly identified organism. Arrange the following steps in a technically logical sequence that the student must follow.
A. Ion-exchange chromatography
B. Salting out
C. Affinity chromatography
D. Size-exclusion chromatography.

Choose the correct answer from the options given below :

QUESTION ID:75

Which of the following amino acids has an aromatic side chain?

QUESTION ID:76

Which of the following amino acids has the highest molecular weight?

QUESTION ID:77

Which of the following components are required for making carbonate buffers?

QUESTION ID:78

Glycolysis is the breakdown of glucose to pyruvate, and gluconeogenesis is the synthesis of glucose from pyruvate. The intermediates involved in these two pathways are the same, but only some of the reactions are reversible, and those are catalyzed by the same enzymes. Which of the following steps is catalyzed by two different enzymes for the two pathways?

QUESTION ID:79

Choose the INCORRECT statement from the following

QUESTION ID:80

Given below two statements :
Statement I : Different cyclins activate CDKs at different cell cycle stages.
Statement II : Each CDK is degraded at the end of the cell cycle phase, where it functions.
In the light of the above statements, choose the most appropriate answer from the options given below

QUESTION ID:81

Arrange the following components of the G-protein-coupled receptor (GPCR) signaling system in the correct order of their functioning.
A. cAMP
B. PKA
C. Guanine nucleotide exchange factor
D. Adenylate cyclase
E. Epinephrine

Choose the correct answer from the options given below :

QUESTION ID:82

Given below are two statements : one is labelled as Assertion A and the other is labelled as Reason R.
Assertion A : The early eukaryotic cells engulfed aerobic bacteria (endosymbiosis) and made it part of the cell body, which eventually became the present-day mitochondria.
Reason R : Such engulfment of aerobic bacterium was just a coincidence without any specific evolutionary objective.
In the light of the above statements, choose the most appropriate answer from the options given below

QUESTION ID:83

Choose the INCORRECT statement about biological membranes

QUESTION ID:84

Choose the INCORRECT statement about the structural stability of proteins from the following.

QUESTION ID:85

Match List I and List II

List I: Type of transposonsList II: Examples
A. DNA transposons, autonomousI. Copia
B. Non-LTR, nonautonomousII. P element
C. LTR, autonomousIII. Tn 10
D. DNA transposons, nonautonomousIV. Alu
Choose the correct answer from the options given below :