Previous Year Questions

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TLS Online TPP Program

QUESTION ID:1

Determine the correctness or otherwise of the following Assertion [a] and the Reason  [r]. 
Assertion [a]: A genetically engineered rice that produces beta-carotene in the rice grain is called Golden rice 
Reason [r]: Enabling biosynthesis of provitamin A in the rice endosperm gives a characteristic yellow/orange color 

QUESTION ID:2

The sequence of a 1 Mb long DNA is random. This DNA has all four bases occurring in equal proportion. The number of nucleotides, on average, between two successive EcoRI recognition site GAATTC is  

QUESTION ID:3

E. coli was grown in 15N medium for several generations. Cells were then transferred to 14N medium, allowed to grow for 4 generations and DNA was isolated immediately. The proportion of total DNA with intermediate density is  (round off to 2 decimal places). 

QUESTION ID:4

A batch reactor is inoculated with 1 g/L biomass. Under these conditions, cells exhibit a lag phase of 30 min. If the specific growth rate in the log phase is 0.00417 min^-I, the time taken for the biomass to increase to 8 g/L is min (round off to 2 decimal places). 

QUESTION ID:5

The system of linear equations cx + y = 5

3x +3y= 6

has no solution when c is equal to  

QUESTION ID:6

The amino acid sequence of a peptide is Phe-Leu-Ile-Met-Ser-Leu. The number of codons that encode the amino acids present in this peptide is given below: 
Phe: 2 codons
Leu: 6 codons
Ile: 3 codons
Met: 1 codon
Ser: 4 codons
The number of unique DNA sequences that can encode this peptide is 

QUESTION ID:7

Assume that a cell culture was started with five human fibroblast cells. Two cells did not divide even once whereas the other three cells completed three rounds of cell division. At this stage, the total number of kinetochores in all the cells put together is 

QUESTION ID:8

Growth of an organism on glucose in a chemostat is characterized by Monod model with specific growth rate = 0.45 11^-1 and Ks = 0.5 g/L. Biomass from the substrate is generated as Yxs = 0.4 g/g. The chemostat volume is 0.9 L and media is fed at 1 L/h and contains 20 g/L of glucose. At steady state, the concentration of biomass in the chemostat is .......  g/L. 

QUESTION ID:9

A function f is given as:  f(X) = 4X — X^2  The function is maximized when X is equal to 

QUESTION ID:10

An infinite series S is given as: S = 1 + 2/3 + 3/9 + 4/27 + 5/81 + (to infinity) The value of S ........  is (round off to 2 decimal places). 

QUESTION ID:11

Protein A and protein B form a covalent complex. Gel filtration chromatography of this complex showed a peak corresponding to 200 kDa. SDS-PAGE analysis of this complex, with and without beta-mercaptoethanol, showed a single band corresponding to molecular weight 50 and 25 kDa, respectively. Given that the molecular weight of protein A is 25 kDa, the molecular weight of protein B is .......  kDa . 

QUESTION ID:12

The concentrations of ATP, ADP and inorganic phosphate in a cell are 2.59, 0.73 and 2.72 mM, respectively. Under these conditions, free energy change for the synthesis of ATP at 37 °C is ...... kJ/mol (round off to 2 decimal places). 
Given: free energy change for ATP hydrolysis under standard conditions is -30.5 kJ/mol and R = 8.315 kJ/mol.K 

QUESTION ID:13

An algorithm was designed to find globins in protein sequence databases. A database which has 78 globin sequences was searched using this algorithm. The algorithm retrieved 72 sequences of which only 65 were globins. The sensitivity of this algorithm is ......  % (round off to 2 decimal places). 

QUESTION ID:14

The mitochondrial electron transfer chain oxidizes NADH with oxygen being the terminal electron acceptor. The redox potentials for the two half-reactions are given below: 
The free energy change associated with the transfer of electrons from NADH to 02 is .........  kJ/mol (round off to 2 decimal places).  Given: F = 96500 C/mol. 


QUESTION ID:15

Rajiv Gandhi Khel Ratna Award was conferred ........  Mary Kom, a six-time world champion in boxing, recently in a ceremony......  the Rashtrapati Bhawan (the President's official residence) in New Delhi. )

QUESTION ID:16

Despite a string of poor performances, the chances of K. L. Rahul's selection in the team are  

QUESTION ID:17

Select the word that fits the analogy: 
Cover : Uncover :: Associate : 

QUESTION ID:18

Hit by floods, the kharif (summer sown) crops in various parts of the country have been affected. Officials believe that the loss in production of the kharif crops can be recovered in the output of the rabi (winter sown) crops so that the country can achieve its food-grain production target of 291 million tons in the crop year 2019-20 (July-June). They are hopeful that good rains in July-August will help the soil retain moisture for a longer period, helping winter sown crops such as wheat and pulses during the November-February period. 
Which of the following statements can be inferred from the given passage? 

QUESTION ID:19

Repo rate is the rate at which Reserve Bank of India (R131) lends commercial banks, and reverse repo rate is the rate at which RBI borrows money from commercial banks. 

Which of the following statements can be inferred from the above passage? 

QUESTION ID:20

P, Q, R, S, T, U, V, and W are seated around a circular table. 1. S is seated opposite to W. II. U is seated at the second place to the right of R. III. T is seated at the third place to the left of R. 1V. V is a neighbor of S. 
Which of the following must be true? 

QUESTION ID:21

The difference between the sum of the first 2n natural numbers and the sum of the first n odd natural numbers is

QUESTION ID:22

The distance between Delhi and Agra is 233 km. A car P started travelling from Delhi to Agra and another car Q started from Agra to Delhi along the same road 1 hour after the car P started. The two cars crossed each other 75 minutes after the car Q started. Both cars were travelling at constant speed. The speed of car P was 10 km/hr more than the speed of car O. How many kilometers the car Q had travelled when the cars crossed each other? 

QUESTION ID:23

For a matrix M = [m ij]; i,j = 1,2,3,4, the diagonal elements are all zero and mij = —mji. The minimum number of elements required to fully specify the matrix is

QUESTION ID:24

The profit shares of two companies P and Q are shown in the figure. If the two companies have invested a fixed and equal amount every year, then the ratio of the total revenue of company P to the total revenue of company Q, during 2013 - 2018 is