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Previous Year Questions

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TLS Online TPP Program

QUESTION ID:1

Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularly closed double stranded DNA. 

QUESTION ID:2

Let U = {1, 2, … , 15}. Let P ⊆ U consist of all prime numbers, Q ⊆ U consist of all even numbers and R ⊆ U consist of all multiples of 3. Let T = P - Q. Then, which of the following is/are CORRECT?

QUESTION ID:3

 Which of the following is/are CORRECT? 

QUESTION ID:4

The characteristic oxygen binding profile of hemoglobin shown below arises due to the ________.


QUESTION ID:5

The advantage(s) of storing chemical energy in the form of starch and not as free glucose is/are that it________. 

QUESTION ID:6

Which of the following cell types can develop from myeloid lineage? 

QUESTION ID:7

Electromagnetic waves _______. 

QUESTION ID:8

Which of the following statement(s) is/are true? 

QUESTION ID:9

BF3 reacts readily with ________. 

QUESTION ID:10

The reaction of (R)-2-bromobutane with CN- proceeds by ________. 

QUESTION ID:11

C3 plants utilize 18 molecules of ATP to synthesize one molecule of glucose from CO2. How many molecules of ATP equivalents are used by C4 plants to synthesize one molecule of glucose from CO2?

QUESTION ID:12

A 0.1% (w/v) solution of a protein absorbs 20% of the incident light. What fraction of light is transmitted if the concentration is increased to 0.4%? [Correct to two decimal places]  

QUESTION ID:13

Let XYZ be an equilateral triangle and let P, Q, R be the mid points of YZ, XZ, and XY, respectively.

The value ofr is _______. 

QUESTION ID:14

Let N be the set of natural numbers and f : N ↦ N be defined by

Let f n(x) denote the n-fold composition of f (x). What is the smallest integer n such that f n(13) =  1 ?

QUESTION ID:15

Heterozygous female fruit flies with gray body and purple eyes were mated with homozygous males with black body and red eyes. The number of offspring obtained and their phenotypes are shown below:

Calculate the recombination frequency.  

QUESTION ID:16

Proinsulin is an 84 residue polypeptide with six cysteines. How many different disulfide combinations are possible?

QUESTION ID:17

The refractive index of a liquid relative to air is 1.5. Calculate the ratio of the real depth to the apparent depth when the liquid is taken in a beaker. 

QUESTION ID:18

A metallic wire of electrical resistance 40 Ω is bent in the form of a square loop. The resistance between any two diagonally opposite corners is ________ Ω.

QUESTION ID:19

The total number of lone pairs of electrons in NO2F is _______.

QUESTION ID:20

The total number of multiplet peaks in the 1H NMR spectrum of 1,3,5-tri-isopropylbenzene in CDCl3 is ________. 

QUESTION ID:21

A schematic representation of restriction fragment length polymorphism (RFLP) analysis of a sample population is shown below. The number of people exhibiting a given pattern is indicated above the lanes

Calculate the frequency of 6.5 kb allele. [Correct to two decimal places]

QUESTION ID:22


QUESTION ID:23

Phosphoglucoisomerase catalyzes the following reaction:


If 0.05% of the original concentration of Glu-6-P remains at equilibrium, then the equilibrium constant of this reaction is________. 

QUESTION ID:24

In a bacterium, a mutation resulted in an increase of KS (substrate-specific constant) for ammonium from 50 µM to 5000 µM without affecting µmax. The specific growth rate (µ) of the mutant growing on 0.5 mM ammonium in the medium decreases by a factor of ________.

QUESTION ID:25

The total number of DNA molecules present after 5 cycles of polymerase chain reaction (PCR) starting with 3 molecules of template DNA is ________.  

QUESTION ID:26

Two identical, infinite conducting plates are kept parallel to each other and are separated by a distance d. The uniform charge densities on the plates are +σ and -σ. The electric field at a point between the two plates is  where n is _______. (ε0 is the permittivity of free space)

QUESTION ID:27

The concentration of NaCl (in mM) formed at the stoichiometric equivalence point when 10 mL of 0.1 M HCl solution is titrated with 0.2 M NaOH solution is ________. (as an integer) 

QUESTION ID:28

The standard emf of a cell (in V) involving the reaction, 2 Ag+ (aq.) → Ag (s) + Ag2+ (aq.) at 298 K is _________. [Correct to two decimal places] 

[Given: Ag+ (aq.) + e → Ag (s); Eo = 0.62 V and Ag2+ (aq.) + e → Ag+ (aq.); Eo = 0.12 V]

QUESTION ID:29

  then the value of α + β + γ 

QUESTION ID:30

An infinitely long solenoid of radius r and number of turns per unit length n carries a steady current I. The ratio of the magnetic fields at a point on the axis of the solenoid to a point r/2 from the axis is _______.