Previous Year Questions

QUESTION ID:2

The membrane phospholipids form bilayer when water is available on all sides, due to

QUESTION ID:3

Which one of the following is not a step in Southern Blot technique?

QUESTION ID:4

The population density of an insect species increases from 50 to 60 in one month. If the birth rate for the period is 0.4, then the death rate is

QUESTION ID:5

A major goal of ‘Golden Rice Project’ is to supply consumers in rice-based societies with recommended daily intake of

QUESTION ID:6

For induction of somatic embryogenesis in higher plants, the cultured friable callus tissue needs to be exposed to

QUESTION ID:7

Glucose-6-phosphate is a substrate or a product in all of the following pathways except

QUESTION ID:8

Which of the following statements is correct?

(i) Numerical taxonomy aims at determining phenetic relationships between organisms or taxa.
(ii) APG system of classification is established by taking the information from recent molecular studies.
(iii) Phylogenetic classification is constructed in such a way that all the descendants of a common ancestor should be placed in the same group, i.e., group should be monophyletic.

QUESTION ID:9

Match the non-protein coding RNA molecules present in genome with their function.

QUESTION ID:10

Which one of the following complexes of Electron Transport System (ETS) does not account for the pumping out of protons from the mitochondrial matrix?

QUESTION ID:11

Chemical that is required for maintaining the protoplasts in intact condition during protoplast culture is

QUESTION ID:12

Individuals with greater mass have a smaller surface area to volume ratio, which helps to conserve heat. This is known as

QUESTION ID:13

In a cell fusion experiment, a cell in S-phase was fused with cells in (a) G₁-phase, (b) G₂-phase, (c) M-phase. The fused cells were grown in medium containing tritium-labelled thymidine. Maximum radiolabel will be obtained in S-phase cell fused with

QUESTION ID:14

In antibody molecules, variable regions are present in

QUESTION ID:15

Which of the following is a constitutive promoter for expression of transgene in monocotyledonous plants?

QUESTION ID:16

The major detoxification reactions in phase-1 involved all of the following except

QUESTION ID:17

Which of the following diseases is associated with protein misfolding?

QUESTION ID:18

Which one of the following statements is not true for the retinal protein bacteriorhodopsin?

QUESTION ID:19

The pygmy hog and the hangul are the representatives of the following Indian States:

QUESTION ID:20

Which of the following statements is not true about Brown fat tissue?

QUESTION ID:21

In a brackishwater shrimp farm, a farmer detected some shrimps with white spots of variable sizes prominently seen on the carapace. It could be caused by a

QUESTION ID:22

In a diploid organism segregation of the two alleles, after a recombination event between the given gene and the centromere of the chromosome, occur at

QUESTION ID:23

Which one of the following serves as the source of CO₂ for the Calvin cycle in C₄ plants?

QUESTION ID:24

Which one of the following neurotransmitters is responsible for awakening from sleep?

QUESTION ID:25

Acquisition of skills for playing piano is an example of

QUESTION ID:26

Methotrexate, an anticancer drug, is an inhibitor of

QUESTION ID:27

Which one of the following does not contribute to the productivity in the marine ecosystem?

QUESTION ID:28

Which one of the following statements about the nucleolus is false?

QUESTION ID:29

The aggregated mass of sterile cells located at the inside base of capsule of Pellia is called

QUESTION ID:30

All of the following statements are true with respect to T-lymphocytes, except:

QUESTION ID:31

If a Drosophila species has 3 pairs of metacentric chromosomes and 1 pair of telocentric chromosome, this species will have

QUESTION ID:32

Out of following enzymes mentioned below, which one is activated by acid hydrolysis of the proenzyme form?

QUESTION ID:33

Which of the following statements is not correct for the phenomenon of photoblastism?

QUESTION ID:34

A phytohormone which is produced by plants under water deficient condition and plays a key role in the tolerance response of plants to drought is

QUESTION ID:35

Which one of the following learning processes belongs to “Associative Learning” type?

QUESTION ID:36

The restriction enzyme EcoRI recognizes and cleaves at
5′ GAATTC 3′
3′ CTTAAG 5′.
What would be the approximate number of DNA fragments produced by cleaving E. coli genome (size ~ 4.60 × 10⁶ bp) with EcoRI?

QUESTION ID:37

If you wish to study the region of binding of a transcription factor to the promoter DNA, which one of the following techniques will be most appropriate?

QUESTION ID:38

Which one of the following statements about Analysis of Variance (ANOVA) is not correct?

QUESTION ID:39

If a sample of DNA is found to have the base composition (mole ratios) as follow:
Adenine – 40; Thymine – 22; Guanine – 21; Cytosine – 17, then which one of the following conclusions will be most appropriate?

QUESTION ID:40

In red algae and in some charophycean green algae, the elongated apical portion of the female gamete (carpogonium or oogonium) that is receptive to male gamete is called

QUESTION ID:41

Which one of the following statements is not correct?

QUESTION ID:42

What would be the frequency of occurrence of Restriction site for Pst I (5′ CTGCAG 3′ / 3′ GACGTC 5′) in a DNA from thermophile with G+C content of 80% in its genome?

QUESTION ID:43

“Agent orange” used as leaf defoliator by US army during Vietnam war was

QUESTION ID:44

Which one of the following brain centers in human is called the trouble shooter in visual function?

QUESTION ID:45

White tailed deers are most active during the twilight hours of dusk and dawn. Which one of the circadian rhythms describes them?

QUESTION ID:46

Which one of the following cutaneous receptors is not activated by steady pressure stimulus?

QUESTION ID:47

The following are some of the statements given for dosage compensation:

(i) In XX individuals inactivation of one of the X-chromosome occurs at early stages of development, not at 1-cell stage.
(ii) X-chromosome inactivation is random, i.e., any of the 2Xs, maternal or paternal gets inactivated.
(iii) In females Sxl mRNA gets alternatively spliced, thus producing functional Sxl protein.
(iv) In males hyperactivation of the only X-chromosome compensates the dosage of X-chromosomal genes.
(v) Females are mosaics for functional maternal or paternal X-chromosome.

Which one of the options given below has all correct statements for dosage compensation in mammals?

QUESTION ID:48

In human, it is usually predicted that half of the babies born will be male and half will be female. Which one of the following is the most appropriate explanation?

QUESTION ID:49

Membrane potential in intact mitochondria will favour finding of which one of the following compounds after passage through the inner mitochondrial membrane?

QUESTION ID:50

A series of five cell lines were created by human-mouse somatic-cell hybridizations. Each cell line was examined for the presence of human chromosomes and for the production of an enzyme. The following results were obtained:

On the basis of the above results, the gene is mapped to chromosome number:

QUESTION ID:51

At which of the following sites, the partial pressure of CO₂ is highest?

QUESTION ID:52

Which amino acid in a polypeptide undergoes N-linked glycosylation in the lumen of the rough endoplasmic reticulum?

QUESTION ID:53

Which one of the following marker systems reveals higher polymorphism?

QUESTION ID:54

Drosophila melanogaster and Drosophila simulans are morphologically similar but reproductively isolated species. They are known as

QUESTION ID:55

Ex-situ bioremediation techniques involve excavation and subsequent transportation of pollutants to another site for treatment. Which of the following techniques is not a part of this process?

QUESTION ID:56

There are two statements, one is Assertion (A) and another is Reason (R).

Assertion (A): The carbon dioxide content of the atmosphere has been rising in past few decades due to burning of fossil fuels.

Reason (R): On an average there is an increase in temperature of 0.4 to 0.5°C per decade.

Select the correct answer from the options given below:

QUESTION ID:57

Which one of the following characters of Anthoceros is shared with that of green algae?

QUESTION ID:58

In Escherichia coli the mismatch repair system repairs the mis-incorporated base which is not removed by the proof reading activity of DNA polymerase. While doing so the repair system has to decide which DNA strand is newly synthesized and which DNA strand is parental. Mismatch repair system does it by recognizing

QUESTION ID:59

The deposition of pollen on the stigma of another flower of the same plant is called

QUESTION ID:60

Which one of the following options has characteristics of a non-poisonous snake?

QUESTION ID:61

Juvenile hormone (JH) regulates development and reproduction in arthropods. Chemically it is a

QUESTION ID:62

Mutable Collagenous Tissue (MCT) is the characteristic of the phylum:

QUESTION ID:63

Which of the following techniques would be the most suitable to identify a micro-deletion?

QUESTION ID:64

Fangs are specialized teeth used for venom deliverance in animals. In snakes, solenoglyphous fangs can be seen in

QUESTION ID:65

Baffles are metal strips attached radially to fermenter wall. The major function of the baffles is to

QUESTION ID:66

Which of the phytohormones is primarily involved in stomatal closure under drought condition?

QUESTION ID:67

Which moiety of haemoglobin molecule binds to 2,3-bisphosphoglycerate at pH 7.0?

QUESTION ID:68

The Gram-negative, motile bacterial species Pseudomonas carboxydovorans is an/a

QUESTION ID:69

In an experiment with Xenopus blastula, some of the animal cap cells that are supposed to be ectodermal in fate, are labelled with fluorescent dye and placed at the floor of the blastocoel. The labelled cells will be fated as

QUESTION ID:70

A blueprint for action plan for protection of The Earth, the “Agenda 21” envisages

QUESTION ID:71

Lactic acid component of human sweat attracts the mosquito, Aedes aegypti, to have a blood meal. This chemical signal emitted by human is an example of

QUESTION ID:72

The following statements are given for the genes/gene products that are involved in giving molecular address to the body parts:

(i) Contains 60 aa homeo domain that fits mainly in the major groove of the downstream genes.
(ii) Act as transcription factors.
(iii) Have four paralogous groups located in different chromosomes.
(iv) The genes are clustered in 2 complexes.

Which combination of above statements is the best appropriate for Drosophila homeotic genes/gene products?

QUESTION ID:73

Cutting the posterior root of a spinal nerve would

QUESTION ID:74

The fish that lives in riverine water and becoming reproductively mature migrates to the sea to breed there is known as

QUESTION ID:75

Two large plasmids of 80 kb and 100 kb have been isolated from Rhizobium sp. Which of the following techniques should be most suitable to resolve these two plasmids?

QUESTION ID:76

The CLAVATA3 (CLV3) — WUSCHEL (WUS) signaling pathway has evolved as the central regulatory pathway that

QUESTION ID:77

A 34 years old man visits a physician with high fever, chill, severe headache and confusion. He has recently returned from Africa after completing an official assignment. A peripheral blood smear reveals multiple ring structures and crescent-shaped gametes. The most likely cause of his complaint is

QUESTION ID:78

‘Molten Globule State’ is associated with

QUESTION ID:79

Which one is a wrong match between the helminth and the disease transmitting invertebrate host?

QUESTION ID:80

After meiosis I, each of the resultant daughter cells possesses:

QUESTION ID:81

In snail Lymnaea peregra, a male homozygous for dextral alleles s⁺ s⁺ is crossed with a female homozygous for sinistral alleles ss (s⁺ is dominant while s is recessive). When F1 individuals of this cross were crossed among themselves, in F2 all progeny individuals had dextral phenotype.

Which of the following options gives a correct explanation for this result?

QUESTION ID:82

Which of the following pairs of antibiotics interact with sterols in cell membrane to form channels through which small molecules leak from the inside of the fungal cell to the outside?

QUESTION ID:83

If the overhead concentration of ozone at a point above The Earth’s surface is 450 DU, what is the thickness in millimeters of pure ozone at 1.0 atm pressure?

QUESTION ID:84

Which class of chemical insecticides is characterized by a relatively high degree of environmental resistance?

QUESTION ID:85

A sample contains four proteins with following properties:

Protein 1 : MW 14000, PI = 10
Protein 2 : MW 62000, PI = 4
Protein 3 : MW 29000, PI = 8
Protein 4 : MW 9000, PI = 5

What will be the order of emergence of these proteins when the mixture of four is chromatographed in anion exchange column at pH 7·0?

QUESTION ID:86

Three different Hfr donor strains are mixed with separate samples of an F⁻ strain and the following mapping data are obtained from the studies of interrupted conjugation:

Hfr 1 : Genes: b⁺ d⁺ c⁺ f⁺ g⁺
Time (min): 5 10 15 25 60

Hfr 2 : Genes: e⁺ f⁺ c⁺ d⁺ b⁺
Time (min): 6 26 36 41 46

Hfr 3 : Genes: c⁺ f⁺ e⁺ g⁺ b⁺
Time (min): 8 18 38 53 78

Which of the following options gives the correct constructed map?

QUESTION ID:87

When DNA is denatured by heating and subsequently allowed to re-anneal, there will be

QUESTION ID:88

p⁵³ protein is associated with all of the following except

QUESTION ID:89

Which of the following statements is not true about telomerase enzyme?

QUESTION ID:90

Analysis of expressed RNA in a cell is known as

QUESTION ID:91

Which of the following statements about Taq polymerase enzyme is not correct?

QUESTION ID:92

Which of the following pairs of antibiotics inhibit bacterial cell wall synthesis but structurally do not contain the four-membered β-lactam ring?

QUESTION ID:93

Which of the following spirochaete is human pathogenic and is designated as “stealth pathogen”?

QUESTION ID:94

Histone acetylation increases transcription of gene because

QUESTION ID:95

The bacterium that oxidizes reduced sulfur compounds (HS^- and SO₃^2-) directly to sulfate (SO₄^2-) with no intermediates is

QUESTION ID:96

Which of the following is an accurate description regarding T-cell’s positive and negative selection in thymus?

QUESTION ID:97

Identify the enzyme that has four different variants, each consisting of a metal center containing any one of the following: ‘Cu–Zn’ or ‘Mn’ or ‘Fe’ or ‘Ni’

QUESTION ID:98

Which of the following statements is not correct for botulinum toxin (BoNT)?

QUESTION ID:99

Which one of the following has isoenzymes? 

QUESTION ID:100

Lyme disease is the most prevalent arthropod borne disease in the United States and is caused by the infection with a