Ptc contains 12 TM α helices and structurally similar

to the Niemann-Pick C1 protein, a cholesterol transporting member of the ABC superfamily

TLS Online TPP Program

#Id: 1421

#Unit 4. Cell Communication and Cell Signaling

Integrins bind extracellular matrix (ECM) glycoproteins, 1. Laminins  

2. Collagens 

3. Fibronectin

4. Vitronectin

TLS Online TPP Program

#Id: 10565

#Unit 4. Cell Communication and Cell Signaling

Ca2+ influx causes the cell and its organelles to swell

and burst, releasing its contents into the extracellular space which trigger activation of immune-system cells

and cause tissue inflammation and damage

TLS Online TPP Program

#Id: 8558

#Unit 1. Molecules and their Interaction Relevant to Biology

Similarly, if the inhibitor binds to a different site from the substrate and reduces the affinity of the enzyme for the substrate without altering the reaction characteristics of that substrate which does bind, then hyperbolic competitive inhibition results

TLS Online TPP Program

#Id: 1602

#Unit 5. Developmental Biology

As cells enter the primitive streak, they undergo an epithelial-to-mesenchymal transformation.

TLS Online TPP Program

#Id: 5876

#Unit 10. Ecological Principles

Atmospheric concentration (ppm)

CO2= 381

Methane= 1.75

Nitrous oxide= .315

Chlorofluorocarbons= 0.0005