The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex. 

TLS Online TPP Program

#Id: 5753

#Unit 10. Ecological Principles

TLS Online TPP Program

#Id: 1673

#Unit 4. Cell Communication and Cell Signaling

Toxoid(inactivated exotoxin)- Diphtheria, Tetanus Subunit- Hepatitis B, Pertussis, Streptococcal pneumonia Conjugate- Haemophilus influenzae type B, Streptococcal pneumonia

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#Id: 7446

#Unit 5. Developmental Biology

Adenylate cyclase A (ACA), is responsible for the synthesis of cAMP.

TLS Online TPP Program

#Id: 8283

#Unit 1. Molecules and their Interaction Relevant to Biology

The dissolution of nonpolar molecules in water is unfavourable because of the large decrease in entropy resulting from clathrate formation, even though the process is exothermic (dH < 0) But unfavourable dG > 0.

  

TLS Online TPP Program

#Id: 8663

#Unit 10. Ecological Principles

Competitive exclusion principle The principle that two species cannot coexist indefinitely when they are both limited by the same resource.