Surface protein on B cell

CR2(CR21)

CD19

TAPA-1(CD81)

mIg 

Igα/ Igβ

(CD79a and CD79B)

TLR

CD40

B7(CD80/86)

ICAM-1

MHC-1 and 2 both

CD 22

TLS Online TPP Program

#Id: 471

#Unit 2. Cellular Organization

Exon sequences are conserved by the negative selection of individuals in which the sequences have changed

TLS Online TPP Program

#Id: 472

#Unit 2. Cellular Organization

Most intron mutations are expected to be selectively neutral except branch site, splicing junctions, and sequences influencing splicing

TLS Online TPP Program

#Id: 473

#Unit 2. Cellular Organization

A mutation that confers a more advantageous phenotype to an organism, relative to Individuals in the same population without the mutation, is positive selection of that organism.

TLS Online TPP Program

#Id: 474

#Unit 2. Cellular Organization

Mutations conferring antibiotic resistance in bacteria or venom-resistance of pray is example of positive selection of mutation in exons

TLS Online TPP Program

#Id: 475

#Unit 2. Cellular Organization

Positive selection in pray population leads to an “arm’s race” with predator (Host-pathogen same).

TLS Online TPP Program

#Id: 476

#Unit 2. Cellular Organization

Two genes may share some related exons but also have unique exons.