BAFF-R expression is first detected in T1 B cells and increases steadily there after.

Signaling through the BAFF/BAFF-R axis promotes survival of transitional B cells by inducing the synthesis of anti-apoptotic factors such as Bcl-2, Bcl-xl, and Mcl-1

TLS Online TPP Program

#Id: 9697

#Unit 4. Cell Communication and Cell Signaling

In resting cells, 

GSK3 is catalytically active which phosphorylates and inhibits glycogen synthase, thus blocking glycogen synthesis from glucose

TLS Online TPP Program

#Id: 9698

#Unit 4. Cell Communication and Cell Signaling

In presence of insulin, 

GSK3 becomes phosphorylated by PKB its catalytic activity is inhibited

TLS Online TPP Program

#Id: 9699

#Unit 4. Cell Communication and Cell Signaling

Insulin stimulated activation of PKB promotes rapid activation of glycogen synthase and glycogen synthesis

TLS Online TPP Program

#Id: 9700

#Unit 4. Cell Communication and Cell Signaling

Mating pathway in the yeast S. cerevisiae, is a MAP kinase cascade which linked to GPCRs.

TLS Online TPP Program

#Id: 9701

#Unit 4. Cell Communication and Cell Signaling

Two mating types of yeast cells are: 

1. a 

2. α

TLS Online TPP Program

#Id: 9702

#Unit 4. Cell Communication and Cell Signaling

Haploid yeast cells secrete protein signals known as pheromones, which induce mating between opposite mating types.