A given MHC molecule can bind numerous different peptides, and some peptides can bind to several different MHC molecules. Because of this MHC molecule is often referred to as “promiscuous”.

TLS Online TPP Program

#Id: 7796

#Unit 2. Cellular Organization

Ran dependent mechanism for nuclear export of cargo proteins containing a leucine-rich nuclear-export signal (NES).

TLS Online TPP Program

#Id: 7797

#Unit 2. Cellular Organization

Exportin 1

a specific nuclear transport receptor for export mechanism

TLS Online TPP Program

#Id: 7798

#Unit 2. Cellular Organization

Exportin-t

functions to export tRNAs & binds fully processed tRNAs in a complex with Ran⋅GTP

TLS Online TPP Program

#Id: 7799

#Unit 2. Cellular Organization

Most mRNAs Are Exported from the Nucleus by a Ran-Independent Mechanism

TLS Online TPP Program

#Id: 7800

#Unit 2. Cellular Organization

The principal nuclear transport receptor of mRNPs out of the nucleus is :

A. mRNP exporter

B. Nuclear export factor 1 (NXF1)

C. Nuclear export transporter 1 (NXT1)

TLS Online TPP Program

#Id: 7801

#Unit 2. Cellular Organization

An RNA helicase (Dbp5) located on the cytoplasmic side of the NPC removes NXF1 and NXT1 from the mRNA in a reaction that is powered by ATP hydrolysis.