Inherited a single mutant NF1 allele then develop neurofibromas, a benign tumor of the sheath cells that surround nerves, caused by loss of both alleles through LOH.

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#Id: 2122

#Unit 8. Inheritance Biology

Inversions that do not include the centromere, are termed paracentric inversions

 

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#Id: 2123

#Unit 8. Inheritance Biology

Pericentric inversion Chromosome inversion that includes the centromere in the inverted region.

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#Id: 2124

#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 2125

#Unit 8. Inheritance Biology

G-banding patterns reveal that several human chromosomes differ from those of chimpanzees by only a pericentric inversion.

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#Id: 2126

#Unit 8. Inheritance Biology

An inversion may break a gene into two parts, with one part moving to a new location and destroying the function of that gene.

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#Id: 2127

#Unit 8. Inheritance Biology

if their positions are altered by an inversion, their expression may be altered, an outcome referred to as a position effect.