E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+

TLS Online TPP Program

#Id: 8183

#Unit 2. Cellular Organization

β oxidation 

A major function of the oxidation reactions is the breakdown of fatty acid molecules.

TLS Online TPP Program

#Id: 8184

#Unit 2. Cellular Organization

β oxidation

In mammalian cells, occurs in mitochondria & peroxisomes.

In yeast and plant cells, occurs in peroxisomes.

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#Id: 8185

#Unit 2. Cellular Organization

Two types of plant peroxisomes:

Present in leaves - participates in photorespiration.

Present in germinating seeds (glyoxysomes) - converts fatty acids into sugars.

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#Id: 8186

#Unit 2. Cellular Organization

Glyoxysomes

Conversion of fats to sugars is accomplished by a series of reactions known as the Glyoxylate cycle

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#Id: 8187

#Unit 2. Cellular Organization

Biosynthetic function of animal peroxisomes- 

Synthesis of cholesterol and dolichol 

Synthesis of bile acids in the liver 

Catalyze the first reactions in the formation of Plasmalogens

TLS Online TPP Program

#Id: 8188

#Unit 2. Cellular Organization

Plasmalogens

• most abundant class of PL in myelin sheaths

• Analogous to PC

• Contain an unusual fatty alcohol that is attached through an ether linkage.