Vitamin D and PTH appear to stimulate production of mature osteoclasts through the dual action:

 1. Inhibiting OPG production

2. Stimulating RANKL formation

TLS Online TPP Program

#Id: 5097

#Unit 6. System Physiology – Plant

Plant phytochrome is an autophosphorylating serine/threonine kinase that may phosphorylate other proteins (X).

TLS Online TPP Program

#Id: 5098

#Unit 6. System Physiology – Plant

The gene that encodes the MYB-related protein is therefore probably a primary response gene, and the LHCB gene itself is probably a secondary response gene.

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#Id: 5099

#Unit 6. System Physiology – Plant

MYB-related protein, now known as circadian clock associated 1 (CCA1), also plays a role in the circadian regulation of LHCB gene expression.

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#Unit 6. System Physiology – Plant

Second but distinct MYB-related protein, late elongated hypocotyl (LHY), has also been identified as a potential clock gene.

TLS Online TPP Program

#Id: 5101

#Unit 6. System Physiology – Plant

When the CCA1 gene is mutated so that no functional protein is produced, circadian and phytochrome regulation of four genes, including LHCB, is affected.

TLS Online TPP Program

#Id: 5102

#Unit 6. System Physiology – Plant

A protein kinase (CK2)CKB3 can interact with and phosphorylate CCA1, which is a multisubunit protein with serine/threonine kinase activity.