Important effect of cortisol, Decrease translocation of GLUT4 to the cell membrane.

TLS Online TPP Program

#Id: 4032

#Unit 7. System Physiology – Animal

Stimulation of the sympathetic cardiac nerves speeds the depolarization in SA node.

TLS Online TPP Program

#Id: 4034

#Unit 7. System Physiology – Animal

The rate of spontaneous discharge increases Norepinephrine secreted by the sympathetic endings binds to β1 receptors

TLS Online TPP Program

#Id: 4035

#Unit 7. System Physiology – Animal

Increase in intracellular cAMP facilitates the opening of L channels, increasing ICa and the rapidity of the depolarization phase of the impulse.

TLS Online TPP Program

#Id: 4036

#Unit 7. System Physiology – Animal

When the cholinergic vagal fibers to nodal tissue are stimulated, the membrane becomes hyperpolarized and the slope of the prepotentials is decreased

TLS Online TPP Program

#Id: 4037

#Unit 7. System Physiology – Animal

Acetylcholine (ACh), released from parasympathetic nerve fibers, activates muscarinic (M2) receptors in the SA node.

TLS Online TPP Program

#Id: 4038

#Unit 7. System Physiology – Animal

activation of the M2 receptors decreases cyclic adenosine 3′,5′-monophosphate (cAMP) in the cells, and this slows the opening of Ca 2+ channels.