Tight junctions seal off body cavities and restrict diffusion of membrane components.

TLS Online TPP Program

#Id: 3327

#Unit 6. System Physiology – Plant

ATP synthase has two components; F1, a peripheral membrane protein, and Fo, oligomycin sensitive

TLS Online TPP Program

#Id: 3329

#Unit 6. System Physiology – Plant

ATP synthase stabilizes ATP relative to ADP + Pi by binding ATP more tightly, releasing enough energy to counterbalance the cost of making ATP.

TLS Online TPP Program

#Id: 3332

#Unit 6. System Physiology – Plant

Careful measurements of the binding constants show that FoF1 binds ATP with very high affinity (K d < 10^-12 M) and ADP with much lower affinity (Kd ≈ 10^-5 M).

TLS Online TPP Program

#Id: 3334

#Unit 6. System Physiology – Plant

Given step with the highest amount of free energy is a rate limiting step

TLS Online TPP Program

#Id: 3336

#Unit 6. System Physiology – Plant

ATP synthesis kinetics is measured by using Kinetic Isotope Effect (KIE) using radioisotope of oxygen ( O¹⁸ ).

TLS Online TPP Program

#Id: 3338

#Unit 6. System Physiology – Plant

F1 has nine subunits of five different types, with the composition α₃ β₃ ϒδε