The central player in the “canonical” Wnt intracellular signal transduction pathway is called β-catenin.

TLS Online TPP Program

#Id: 8378

#Unit 2. Cellular Organization

The first myosin discovered

Myosin II, was isolated from skeletal muscle.

TLS Online TPP Program

#Id: 8379

#Unit 2. Cellular Organization

Three classes of myosins:

Myosin I

Myosin II

Myosin V

TLS Online TPP Program

#Id: 8380

#Unit 2. Cellular Organization

single head domain

Function- Membrane association, endocytosis

TLS Online TPP Program

#Id: 8381

#Unit 2. Cellular Organization

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction

TLS Online TPP Program

#Id: 8382

#Unit 2. Cellular Organization

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport

TLS Online TPP Program

#Id: 8383

#Unit 2. Cellular Organization

All Myosins move toward the (+) end of an actin filament except myosin VI. Myosin VI move toward the (−) end of an actin filament