For good vaccine

a. The vaccine must be safe

b. It must be effective in preventing infection

c. Activation of the humoral and cell-mediated

d. Development of long-term immunologic memory

TLS Online TPP Program

#Id: 796

#Unit 3. Fundamental Processes

Nonsense mutation in one gene of a transcription unit was found to prevent the expression of subsequent genes in the unit even though both genes had their own ribosome binding sites, an effect called polarity.

TLS Online TPP Program

#Id: 797

#Unit 3. Fundamental Processes

There are proteins so-called nut sites in the leader regions of both the 16S and 23S rRNA transcripts, forming antitermination complexes that inhibit the action of rho.

TLS Online TPP Program

#Id: 798

#Unit 3. Fundamental Processes

rho mutants are usually leaky

TLS Online TPP Program

#Id: 799

#Unit 3. Fundamental Processes

Mutations in the rpoB gene can reduce termination at a rho-dependent site.  Mutations in rpoB can restore the ability to terminate transcription at rho-dependent sites in rho mutant bacteria.

TLS Online TPP Program

#Id: 800

#Unit 3. Fundamental Processes

Transcription is formation of RNA from genome (DNA/RNA)

TLS Online TPP Program

#Id: 801

#Unit 3. Fundamental Processes

On the basis of Transcription, viruses have been classified called as Baltimore Classification