Non - templated N nucleotide addition in heavy chains results from TdT activity.

TLS Online TPP Program

#Id: 9720

#Unit 4. Cell Communication and Cell Signaling

Activated Ste12, induces expression of proteins

involved in mating-specific cellular responses.

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#Id: 9956

#Unit 4. Cell Communication and Cell Signaling

Human genome encodes 19 different Wnt proteins, and essential for critical developmental events, including:

Brain development

Limb patterning

Organogenesis

Formation of osteoblasts

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#Id: 9957

#Unit 4. Cell Communication and Cell Signaling

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins

TLS Online TPP Program

#Id: 9958

#Unit 4. Cell Communication and Cell Signaling

Structure of Wnt proteins 

22 cysteine residues, which form disulfide bridges that maintain a globular secondary structure.

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#Id: 9959

#Unit 4. Cell Communication and Cell Signaling

Wnt = wingless + integrated

TLS Online TPP Program

#Id: 9960

#Unit 4. Cell Communication and Cell Signaling

Wnt proteins are modified by linkage of a monounsaturated fatty acid, palmitoleic acid, to a serine in the middle of the protein.