RAG1 subunit and contains two aspartic acid residues and one glutamic acid residue (D600, D708, and E962, respectively). This active site “DDE motif” is found in many enzymes that cleave DNA

TLS Online TPP Program

#Id: 4755

#Unit 5. Developmental Biology

The SKN-1 protein is a transcription factor that initiates the activation of those genes responsible for forming the pharynx and intestine.

TLS Online TPP Program

#Id: 4756

#Unit 5. Developmental Biology

The SKN-1 protein is a maternally expressed transcription factor that controls the fate of the P1 blastomere(P1🡪EMS 🡪MS), that generates the posterior pharynx.

TLS Online TPP Program

#Id: 4757

#Unit 5. Developmental Biology

Embryos from homozygous skn-1-deficient mothers lack both pharyngeal mesoderm & endoderm derivatives of EMS.

TLS Online TPP Program

#Id: 4758

#Unit 5. Developmental Biology

skn-1-deficient embryos make extra hypodermal (skin) & body wall tissue.

TLS Online TPP Program

#Id: 4759

#Unit 5. Developmental Biology

PAL-1 activity is needed for the normal development of the somatic (but not the germline) descendants of the P2 blastomere, specifies muscle production.

TLS Online TPP Program

#Id: 4760

#Unit 5. Developmental Biology

Embryos lacking PAL-1 have no somatic cell types derived from the C and D stem cells.