TLS Online TPP Program

#Id: 3120

#Unit 3. Fundamental Processes

oriC contains binding sites for DnaA: dnaA-boxes.

TLS Online TPP Program

#Id: 3122

#Unit 3. Fundamental Processes

oriC also contains 11 GATC/CTAG repeats that are methylated on adenine on both strands.

TLS Online TPP Program

#Id: 3123

#Unit 3. Fundamental Processes

Replication generates hemimethylated DNA, which cannot initiate replication

TLS Online TPP Program

#Id: 3124

#Unit 3. Fundamental Processes

There is a 13-minute delay before the GATC/CTAG repeats are remethylated. 

TLS Online TPP Program

#Id: 3126

#Unit 3. Fundamental Processes

oriC contains binding sites for DnaA: dnaA-boxes.DnaA is an ATP-bindingprotein and its binding to DNA is affected depending on whether ATP, ADP, or no nucleotide is bound.

TLS Online TPP Program

#Id: 3127

#Unit 3. Fundamental Processes

One mechanism by which the activity of the replication origin is controlled is DNA methylation.