The α-amanitin binding site is beneath a “bridge helix” extending across the cleft between the two largest pol II subunits, Rpb1 and Rpb2

TLS Online TPP Program

#Id: 3107

#Unit 3. Fundamental Processes

A replication fork is initiated at the origin and then moves sequentially along DNA

TLS Online TPP Program

#Id: 3108

#Unit 3. Fundamental Processes

replication fork is initiated at the origin and then moves sequentially along DNA

TLS Online TPP Program

#Id: 3109

#Unit 3. Fundamental Processes

Replication is unidirectional when a single replication fork is created at an origin.

TLS Online TPP Program

#Id: 3110

#Unit 3. Fundamental Processes

Replication is bidirectional when an origin creates two replication forks that move in opposite directions.

TLS Online TPP Program

#Id: 3111

#Unit 3. Fundamental Processes

The replicated region appears as a replication bubble within the nonreplicated DNA. 

TLS Online TPP Program

#Id: 3112

#Unit 3. Fundamental Processes

A replication bubble forms a θ structure in circular DNA.