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TLS Online TPP Program

#Id: 1998

The rapid phase requires the binding of multiple copies of a poly(A)-binding protein containing the RRM motif 


#Unit 3. Fundamental Processes #Polyadenylation #Part B Pointers
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TLS Online TPP Program

#Id: 8149

#Unit 2. Cellular Organization

ARF and Sar1 similar to Ras
TLS Online TPP Program

#Id: 8150

#Unit 2. Cellular Organization

Sar1 is the only GTPase switch protein activated at the ER membrane
TLS Online TPP Program

#Id: 8151

#Unit 2. Cellular Organization

Sec12
acts as a GEF factor for Sar1
TLS Online TPP Program

#Id: 8152

#Unit 2. Cellular Organization

After the vesicle coat is complete, the Sec23 coat subunit promotes GTP hydrolysis causes disassembly of the coat.
TLS Online TPP Program

#Id: 8153

#Unit 2. Cellular Organization

A second function of small GTPases in vesicle formation is in the pinching off of a completed vesicle from the parent membrane
TLS Online TPP Program

#Id: 8154

#Unit 2. Cellular Organization

Sar1 GTPase drives the pinching off of COPII vesicles
ARF GTPase drives the pinching off of COPIvesicles
Dynamin GTPase drives the pinching off of clathrin-coated vesicles