Nurturing Life Sciences
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#Unit 5. Developmental Biology
The Dorsal blastopore region of amphibian embryo- Organizer
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Dorsal most vegetal cells of the blastula, which are capable of inducing the organizer Nieuwkoop center
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The major candidate that forms the Nieuwkoop center in these vegetal cells β-catenin
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During first cleavage, GBP, Dsh, and Wnt11 are brought into the future dorsal section of the embryo Protect β-catenin
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Twin and Siamois encode homeodomain transcription factors and are expressed in the organizer
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High β-catenin + Nodal related high + Veg T, Vg1 = Organizer