Autosomal Recessive Trait

a. Usually appears in both sexes with equal frequency.

b. Tends to skip generations.

c. Affected offspring are usually born to unaffected parents.

d. When both parents are heterozygous, approximately one-fourth of the offspring will be affected.

e. Appears more frequently among the children of consanguineous marriages.

TLS Online TPP Program

#Id: 1625

#Unit 4. Cell Communication and Cell Signaling

Surfactant proteins SP-A, SP-D Block bacterial surface components; promotes phagocytosis.

TLS Online TPP Program

#Id: 1626

#Unit 4. Cell Communication and Cell Signaling

calprotectin Binds and sequesters divalent cations, limiting growth of bacteria and fungi.

TLS Online TPP Program

#Id: 1627

#Unit 4. Cell Communication and Cell Signaling

Psoriasin Binds and sequesters divalent cations

TLS Online TPP Program

#Id: 1628

#Unit 4. Cell Communication and Cell Signaling

(C1s)2 are serine proteases, cleaves C4 and C2  has the same functions as Masp-1 and Masp-2.

TLS Online TPP Program

#Id: 1629

#Unit 4. Cell Communication and Cell Signaling

Alternative tickover pathway is initiated when C3 hydrolysed its internal thioester bond, yielding the molecule C3(H2O), in the presence of serum Mg2 binds another serum protein, factor B.

TLS Online TPP Program

#Id: 1630

#Unit 4. Cell Communication and Cell Signaling

C5b component is extremely labile, is not covalently bound to the membrane like C3b and C4b, and is rapidly inactivated unless it is stabilized by the binding of C6.