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TLS Online TPP Program

#Id: 2232

De novo genes -New Genes in organisms ranging from yeast to humans that did indeed originate from noncoding DNA,

#Unit 11. Evolution and Behavior #Origin of new genes and proteins #Part B Pointers
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TLS Online TPP Program

#Id: 9064

#Unit 4. Cell Communication and Cell Signaling

The activities of GPK and GP are inhibited by a phosphatase called phosphoprotein phosphatase.
TLS Online TPP Program

#Id: 9065

#Unit 4. Cell Communication and Cell Signaling

The promoter or enhancer segments of all genes regulated by PKA contain a cis-acting DNA sequence, the cAMP-response element (CRE), which
contains the highly conserved nucleotide sequence,
5'-TGACGTCA-3'.
TLS Online TPP Program

#Id: 9066

#Unit 4. Cell Communication and Cell Signaling

In nucleus PKA phosphorylate serine-133 on a transcription factor called CREbinding (CREB) protein
TLS Online TPP Program

#Id: 9067

#Unit 4. Cell Communication and Cell Signaling

Phosphorylated CREB binds to CRE-containing target genes and also binds to the co-activator termed CBP/P300, thereby stimulating gene transcription
TLS Online TPP Program

#Id: 9068

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9069

#Unit 4. Cell Communication and Cell Signaling

Inactive PKA is a tetramer consisting of- 
two regulatory (R) subunits
two catalytic (C) subunits