During initial transcription, the polymerase remains stationary on the promoter, unwinds downstream DNA, and pulls that DNA into itself

TLS Online TPP Program

#Id: 8852

#Unit 2. Cellular Organization

Geminin contains a destruction box at its N-terminus that is recognized by APC/Ccdh1, causing it to be ubiquitinylated in late anaphase and degraded by proteasomes.

TLS Online TPP Program

#Id: 5917

#Unit 3. Fundamental Processes

The holoenzyme is a complex of 900 kD that contains 10 different proteins organized into four types of subcomplex

1. Atleast two copies of the catalytic core.

2. two copies of the dimerizing subunit, t, which link the two catalytic cores together.

3. There are two copies of the clamp

4. The g complex is a group of seven proteins, encoded by five genes, that comprise the clamp loader

TLS Online TPP Program

#Id: 3202

#Unit 3. Fundamental Processes

Repair systems recognize DNA sequences that do not conform to standard base pairs.

TLS Online TPP Program

#Id: 5991

#Unit 3. Fundamental Processes

Eukaryotic replication is similar in most aspects to bacterial replication. It is semiconservative, bidirectional, and semidiscontinuous.

TLS Online TPP Program

#Id: 9978

#Unit 4. Cell Communication and Cell Signaling

β-catenin binds to TCF to displace the Gro repressor and recruits co-activator proteins Pygo, LGS, to activate target gene expression.