The transition from the closed to the open complex involves structural changes in the enzyme and the opening of the DNA double helix to reveal the template and nontemplate strands. This “melting” occurs between positions –11 and +2, with respect to the transcription start site.

TLS Online TPP Program

#Id: 653

#Unit 3. Fundamental Processes

A more potent mutagen translates into a greater number of revertant colonies.

TLS Online TPP Program

#Id: 654

#Unit 3. Fundamental Processes

Reversal of the mutation can only be done by same mutagen which created forward mutation.

TLS Online TPP Program

#Id: 655

#Unit 3. Fundamental Processes

The telomere is absolutely required for the stability of the chromosome end.

TLS Online TPP Program

#Id: 656

#Unit 3. Fundamental Processes

The same type of telomeric sequence is found in plants and humans so conserved in nature.

TLS Online TPP Program

#Id: 657

#Unit 3. Fundamental Processes

 Telomeric sequences can be written in the general form Cn(A/T)m, where n >1 and m is 1 to 4.

TLS Online TPP Program

#Id: 658

#Unit 3. Fundamental Processes

TTAGGG repeats with size of 3–20-kb are telomeres of human chromosomes.