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TLS Online TPP Program

#Id: 2523

Microchip electrophoresis is also based on free flow.

#Unit 13. Methods in Biology #Electrophoresis #Part B Pointers
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TLS Online TPP Program

#Id: 8340

#Unit 2. Cellular Organization

Gelsolin, is regulated by Ca+2 ion concentration and sever actin filaments.
TLS Online TPP Program

#Id: 8341

#Unit 2. Cellular Organization

Two major classes of actin-nucleating proteins:

1. Formins nucleate the assembly of unbranched filaments 

2. Arp2/3 complex nucleates the assembly of branched actin networks
TLS Online TPP Program

#Id: 8342

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8343

#Unit 2. Cellular Organization

formin family members have two adjacent domains:

FH1- rich in proline, landing site for profilin–ATP–G-actin

FH2 - form a dimer and nucleate filament assembly
TLS Online TPP Program

#Id: 8345

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8346

#Unit 2. Cellular Organization

Formins are activated by membrane-bound Rho-GTP, a Ras-related small GTPase