5′ nuclease assay (TaqMan assay). PCR is undertaken with a fluorescence reporter/quencher pair (called RQ probe). 

TLS Online TPP Program

#Id: 1218

#Unit 7. System Physiology – Animal

When extracellular Ca2+ concentration is increased  Ca2+ binds to the receptor  activates phospholipase C inhibits PTH secretion.

TLS Online TPP Program

#Id: 1219

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion

TLS Online TPP Program

#Id: 1220

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion

TLS Online TPP Program

#Id: 1221

#Unit 7. System Physiology – Animal

The receptor for PTH is coupled, via a Gs protein, to adenylyl cyclase.

TLS Online TPP Program

#Id: 1222

#Unit 7. System Physiology – Animal

In bone, PTH receptors are located on osteoblasts but not on osteoclasts.

TLS Online TPP Program

#Id: 1223

#Unit 7. System Physiology – Animal

PTH stimulates osteoclast activity and bone resorption by maturation of osteoclast cells.