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TLS Online TPP Program

#Id: 2603

The SNP mutation responsible for sickle-cell disease changes amino acid 6 in haemoglobin β from glutamic acid (E) to valine (V). 

#Unit 13. Methods in Biology #PCR #Part B Pointers
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TLS Online TPP Program

#Id: 1775

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 1776

#Unit 4. Cell Communication and Cell Signaling

In the presence of antigen and TGF-β, CD8+ regulatory T cells expressing FoxP3 can be induced (iTREG).
TLS Online TPP Program

#Id: 1777

#Unit 4. Cell Communication and Cell Signaling

Three main pathways of CD8+ regulatory T cells:
a. APC lysis
b. Inhibition of APC function
c. Regulation of effector T cells
TLS Online TPP Program

#Id: 1778

#Unit 4. Cell Communication and Cell Signaling

TREG cells were most recently characterized as a unique subset of CD4+ T cells that express high levels of the IL-2R  chain (CD25), the low-affinity receptor for this cytokine.
TLS Online TPP Program

#Id: 1779

#Unit 4. Cell Communication and Cell Signaling

High levels of CD25 was responsible for the suppression of diabetes. 
TLS Online TPP Program

#Id: 1780

#Unit 4. Cell Communication and Cell Signaling