The run-on assay can also be used to determine the effects of assay conditions on nuclear transcription.

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#Id: 987

#Unit 5. Developmental Biology

In Drosophila, mid-blastula transition slowdown of nuclear division, cellularization, and concomitant increase in new RNA transcription

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#Id: 7786

#Unit 2. Cellular Organization

NLSs were first discovered through the analysis of mutations of the gene for large T-antigen encoded by simian virus 40 (SV40).

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#Id: 2080

#Unit 8. Inheritance Biology

Edwards syndrome (trisomy 18) occurs when a person has an extra copy of chromosome 18.

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#Id: 10039

#Unit 4. Cell Communication and Cell Signaling

Activated IRAK1/2, binds TRAF6, an E3 ubiquitin ligase, to the signalsome, and promotes the formation of an extended 2-D lattice formed by TRAF6-TRAF6 interactions.

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#Unit 3. Fundamental Processes

Negative control of the lac operon. 

No lactose; repression. The lacI gene produces repressor, which binds to the operator and blocks RNA polymerase from transcribing the lac genes.