On the leading strand (sometimes called the forward strand) DNA synthesis can proceed continuously in the 5 ' to 3’ direction as the parental duplex is unwound.

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#Unit 1. Molecules and their Interaction Relevant to Biology

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#Unit 1. Molecules and their Interaction Relevant to Biology

Lineweaver-Burk plot showing the effect of uncompetitive inhibition; (b) the same, showing plots for several inhibitor concentrations at fixed enzyme concentration.

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#Unit 1. Molecules and their Interaction Relevant to Biology

Non-competitive inhibition 

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#Unit 1. Molecules and their Interaction Relevant to Biology

A non-competitive inhibitor can combine with an enzyme molecule to produce a dead-end complex.

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#Unit 1. Molecules and their Interaction Relevant to Biology

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#Unit 1. Molecules and their Interaction Relevant to Biology