Xeroderma pigmentosum (XP) is a human disease caused by mutations in any one of several nucleotide excision repair genes.

TLS Online TPP Program

#Id: 456

#Unit 2. Cellular Organization

Histone codes are specific and conserved residues that undergoes to modification and changes expression of chromatin.

TLS Online TPP Program

#Id: 457

#Unit 2. Cellular Organization

Histone tail modifications 

TLS Online TPP Program

#Id: 458

#Unit 2. Cellular Organization

Bromodomains recognize acetylated lysine.

TLS Online TPP Program

#Id: 459

#Unit 2. Cellular Organization

The chromodomain is a common protein motif of 60 amino acid that recognizes methylated lysine and Arg. 

TLS Online TPP Program

#Id: 460

#Unit 2. Cellular Organization

PHD and the Tudor domain also recognizes methyl-lysine.

TLS Online TPP Program

#Id: 461

#Unit 2. Cellular Organization

Parity rules were given by Erwin Chargaff

I. Rule of complementarity 

II. Rule of Equal amount applies more closely to introns than to exons

III. Cluster rule – Purines in nontemplate strand applies more closely to Exons