Potent form of benzo(a)pyrene induces inactivating mutations at codons 175, 248, & 273 of the p53 gene.

TLS Online TPP Program

#Id: 1479

#Unit 4. Cell Communication and Cell Signaling

Characterization of the disease-causing deletion showed that the absence of two miRNAs, miR-15-a and miR-16-1, causes chronic lymphocytic leukemia (CLL)

TLS Online TPP Program

#Id: 9893

#Unit 4. Cell Communication and Cell Signaling

Toll-Like Receptors Recognize Many Types of Pathogen Molecules - Vertebrate Toll-like receptors  are dimers of chains with extracellular leucine-rich (LRR) domains that bind PAMPs and DAMPs. 

TLS Online TPP Program

#Id: 6496

#Unit 3. Fundamental Processes

TFIIH is the only general transcription factor that has multiple independent enzymatic activities. Its several activities include an ATPase, helicases of both polarities, and a kinase activity that can phosphorylate the CTD tail of RNA polymerase II (on serine 5 of the heptapeptide repeat). TFIIH is an exceptional factor that may also play a role in elongation.

TLS Online TPP Program

#Id: 8002

#Unit 10. Ecological Principles

Ecological niche modeling - The process of determining the suitable habitat conditions for a species.

TLS Online TPP Program

#Id: 1014

#Unit 5. Developmental Biology

A fruit fly’s sex is determined predominantly by the number of X chromosomes in each cell.