Nurturing Life Sciences
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#Unit 13. Methods in Biology
The efficiency of FRET is inversely proportional to the sixth power of the distance between donor and acceptor.
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Most STRs are found in the noncoding regions, while only about 8% locate in the coding regions.
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The genetic diseases caused by trinucleotide repeat SSRs within genes. Huntington disease (HD) is one of the approximately 20 such trinucleotide repeat diseases in humans. HD is transmitted as an autosomal dominant mutation.
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In humans, chromosome 19 has the highest density of STRs. Disease associated with SSR are called as Repeat expansion diseases.