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TLS Online TPP Program

#Id: 3654

The translation machinery relies on the high fidelity of the aminoacyl-tRNA synthetases to ensure the accurate decoding of each mRNA.

#Unit 3. Fundamental Processes #Translation initiation factors and their regulation #Part B Pointers
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TLS Online TPP Program

#Id: 10077

#Unit 4. Cell Communication and Cell Signaling

An integrin molecule is composed of two noncovalently associated transmembrane glycoprotein subunits called α and β.
TLS Online TPP Program

#Id: 10078

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 10079

#Unit 4. Cell Communication and Cell Signaling

Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton.
TLS Online TPP Program

#Id: 10080

#Unit 4. Cell Communication and Cell Signaling

Integrins bind extracellular matrix (ECM) glycoproteins, 
1. Laminins  
2. Collagens 
3. Fibronectin
4. Vitronectin
TLS Online TPP Program

#Id: 10081

#Unit 4. Cell Communication and Cell Signaling

Fibronectin binds to integrin through an RGD motif.
TLS Online TPP Program

#Id: 10082

#Unit 4. Cell Communication and Cell Signaling

The binding of integrins to their ligands depends on extracellular divalent cations(Ca+2 & Mg+2)