activation of the M2 receptors decreases cyclic adenosine 3′,5′-monophosphate (cAMP) in the cells, and this slows the opening of Ca 2+ channels.

TLS Online TPP Program

#Id: 1274

#Unit 7. System Physiology – Animal

Angiotensin II stimulates the synthesis and secretion of aldosterone by the activation of phospholipase C via Gq. 

TLS Online TPP Program

#Id: 1275

#Unit 7. System Physiology – Animal

Important effect of cortisol, Decrease translocation of GLUT4 to the cell membrane.

TLS Online TPP Program

#Id: 1276

#Unit 7. System Physiology – Animal

Cortisol induces the synthesis of lipocortin, an inhibitor of the enzyme PLA2. 

TLS Online TPP Program

#Id: 1277

#Unit 7. System Physiology – Animal

Cortisol inhibits the production of interleukin-2 and the proliferation of T lymphocytes.

TLS Online TPP Program

#Id: 1278

#Unit 7. System Physiology – Animal

Addison disease (primary adrenocortical insufficiency) caused by autoimmune destruction of all zones of the adrenal cortex.

TLS Online TPP Program

#Id: 1279

#Unit 7. System Physiology – Animal

Cushing syndrome Chronic excess of glucocorticoids (hypersecretion of ACTH from a pituitary adenoma)