Histological samples are often stained with hematoxylin and eosin (“H&E stain”).

TLS Online TPP Program

#Id: 2106

#Unit 8. Inheritance Biology

Prader–Willi syndrome- Deletion on 15 long arm

TLS Online TPP Program

#Id: 2107

#Unit 8. Inheritance Biology

Deletion of a number of pairs that is not evenly divisible by three will lead to a frameshift mutation.

TLS Online TPP Program

#Id: 2108

#Unit 8. Inheritance Biology

In an individual heterozygous for a deletion, the normal chromosome loops out during chromosome pairing in prophase I.

 

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#Id: 2109

#Unit 8. Inheritance Biology

Deletion includes the centromere, then the chromosome will not segregate in meiosis or mitosis and will usually be lost.

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#Id: 2110

#Unit 8. Inheritance Biology

Deletions are lethal in the homozygous state because all copies of any essential genes located in the deleted region are missing.

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#Id: 2111

#Unit 8. Inheritance Biology

Heterozygous condition may produce imbalances in the amounts of gene products similar to those produced by extra gene copies.