When the fitness interests of two individuals are different, they are in conflict.

The evolution of cooperation and conflict depends on when these kinds of behaviors are favored by natural selection.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Fibronectin binds to integrin through an RGD motif.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

The binding of integrins to their ligands depends on extracellular divalent cations(Ca+2 & Mg+2)

TLS Online TPP Program

#Id: 10083

#Unit 4. Cell Communication and Cell Signaling

The α subunit of each integrin is the primary determinant of its extracellular ligand specificity

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Several integrin α subunits contain, I-domain, which can mediate binding of integrins to various collagens in the ECM.

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#Id: 10085

#Unit 4. Cell Communication and Cell Signaling

I-domains also recognize CAMs on other cells, 

ICAMs, VCAMs and participate in cell-cell adhesion.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

The non-I-domain α subunits recognize RGD motif.